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GO:0006298 mismatch repair

A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.

Term Information

ID GO:0006298
Name mismatch repair
Ontology Biological Process
Definition A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.
Comment

Synonyms

Type Synonym
narrow long patch mismatch repair system
related MutS/MutL/MutH pathway
related mismatch repair, MutL-like pathway
exact MMR

Cross-references associated with this term:

Database ID
INTERPRO IPR011184
INTERPRO IPR016151
INTERPRO IPR011186
INTERPRO IPR004603
INTERPRO IPR007695
INTERPRO IPR007861
INTERPRO IPR003310
INTERPRO IPR000432
INTERPRO IPR005748
INTERPRO IPR013507
INTERPRO IPR007696
INTERPRO IPR007860
Wikipedia DNA_mismatch_repair
INTERPRO IPR002099

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Ancestor Chart

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Ancestor Table

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0050896 response to stimulus
GO:0008152 metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0043170 macromolecule metabolic process
GO:0044238 primary metabolic process
GO:0006950 response to stress
GO:0006974 response to DNA damage stimulus
GO:0043283 biopolymer metabolic process
GO:0044237 cellular metabolic process
GO:0051716 cellular response to stimulus
GO:0033554 cellular response to stress
GO:0044260 cellular macromolecule metabolic process
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0034984 cellular response to DNA damage stimulus
GO:0034960 cellular biopolymer metabolic process
GO:0006259 DNA metabolic process
GO:0006281 DNA repair
GO:0006298 mismatch repair

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
R GO:0032423 regulation of mismatch repair
NR GO:0032424 negative regulation of mismatch repair
PR GO:0032425 positive regulation of mismatch repair
I GO:0000710 meiotic mismatch repair
I GO:0070716 mismatch repair involved in maintenance of fidelity during DNA-dependent DNA replication

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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