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GO:0006281 DNA repair

The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

Term Information

ID GO:0006281
Name DNA repair
Ontology Biological Process
Definition The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
Comment

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_pir470
goslim_pombe48

Cross-references associated with this term:

Database ID
INTERPRO IPR007581
INTERPRO IPR018078
INTERPRO IPR000977
INTERPRO IPR003021
INTERPRO IPR014048
INTERPRO IPR015967
INTERPRO IPR005101
INTERPRO IPR012309
INTERPRO IPR003717
INTERPRO IPR018982
INTERPRO IPR004574
INTERPRO IPR004576
INTERPRO IPR004577
INTERPRO IPR004579
INTERPRO IPR004580
INTERPRO IPR004582
INTERPRO IPR004584
INTERPRO IPR004585
INTERPRO IPR004586
INTERPRO IPR004595
INTERPRO IPR004598
INTERPRO IPR004600
INTERPRO IPR004604
INTERPRO IPR004605
INTERPRO IPR004609
INTERPRO IPR004610
INTERPRO IPR004612
INTERPRO IPR006310
INTERPRO IPR011364
INTERPRO IPR011370
INTERPRO IPR003011
INTERPRO IPR004791
INTERPRO IPR004808
INTERPRO IPR012112
INTERPRO IPR008822
INTERPRO IPR008823
INTERPRO IPR008824
INTERPRO IPR006050
INTERPRO IPR006084
INTERPRO IPR006085
INTERPRO IPR006086
INTERPRO IPR018324
INTERPRO IPR007268
INTERPRO IPR004026
INTERPRO IPR001679
INTERPRO IPR001719
INTERPRO IPR015236
INTERPRO IPR011257
INTERPRO IPR005118
INTERPRO IPR000191
INTERPRO IPR002081
INTERPRO IPR017962
INTERPRO IPR017963
INTERPRO IPR017961
INTERPRO IPR007198
INTERPRO IPR007232
INTERPRO IPR001238
INTERPRO IPR008332
INTERPRO IPR011114
Wikipedia DNA_repair
INTERPRO IPR001126
INTERPRO IPR004035
INTERPRO IPR004036
INTERPRO IPR000035
INTERPRO IPR000085
INTERPRO IPR000093
INTERPRO IPR000097
INTERPRO IPR002008
INTERPRO IPR011938
INTERPRO IPR011939
INTERPRO IPR011941
INTERPRO IPR018381
INTERPRO IPR006642
INTERPRO IPR018085
INTERPRO IPR001405
INTERPRO IPR000305
INTERPRO IPR002176
INTERPRO IPR003583
INTERPRO IPR013849
INTERPRO IPR006932
INTERPRO IPR000212
INTERPRO IPR000214
INTERPRO IPR004149
INTERPRO IPR004150
INTERPRO IPR006167
INTERPRO IPR013620
INTERPRO IPR005227
INTERPRO IPR015887
INTERPRO IPR000686
INTERPRO IPR010347
INTERPRO IPR015361
INTERPRO IPR008148
INTERPRO IPR007517
INTERPRO IPR004504
INTERPRO IPR012170
INTERPRO IPR001497
INTERPRO IPR018394
INTERPRO IPR003561
INTERPRO IPR003562
INTERPRO IPR003563
INTERPRO IPR003564
INTERPRO IPR015637
INTERPRO IPR012092
INTERPRO IPR012310
INTERPRO IPR018239
INTERPRO IPR018246
INTERPRO IPR012308

This term can be used instead of these obsolete terms:

GO:0006280 mutagenesis (consider GO:0006281)

Web service: term information

Use this URI template to access this data as a service:

GTerm?id=termID&format=format

Full details can be found on the QuickGO Web Services page.

Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.

Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0008150 biological_process
GO:0009987 cellular process
GO:0050896 response to stimulus
GO:0008152 metabolic process
GO:0044238 primary metabolic process
GO:0043170 macromolecule metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0006950 response to stress
GO:0044237 cellular metabolic process
GO:0006974 response to DNA damage stimulus
GO:0051716 cellular response to stimulus
GO:0043283 biopolymer metabolic process
GO:0044260 cellular macromolecule metabolic process
GO:0033554 cellular response to stress
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0034984 cellular response to DNA damage stimulus
GO:0034960 cellular biopolymer metabolic process
GO:0006259 DNA metabolic process
GO:0006281 DNA repair

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
P GO:0051103 DNA ligation during DNA repair
R GO:0006282 regulation of DNA repair
I GO:0046787 viral DNA repair
P GO:0000731 DNA synthesis during DNA repair
I GO:0010213 non-photoreactive DNA repair
I GO:0043504 mitochondrial DNA repair
I GO:0000012 single strand break repair
I GO:0006298 mismatch repair
I GO:0006301 postreplication repair
I GO:0006302 double-strand break repair
I GO:0006307 DNA dealkylation
I GO:0045004 DNA replication proofreading
I GO:0045020 error-prone DNA repair
I GO:0045021 error-free DNA repair
I GO:0006290 pyrimidine dimer repair
I GO:0000725 recombinational repair
I GO:0000726 non-recombinational repair
I GO:0006284 base-excision repair
I GO:0006289 nucleotide-excision repair
NR GO:0045738 negative regulation of DNA repair
PR GO:0045739 positive regulation of DNA repair
I GO:0070914 UV-damage excision repair

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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