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GO:0006273 lagging strand elongation

Term Information

ID GO:0006273
Name lagging strand elongation
Ontology Biological Process
Definition The synthesis of DNA from a template strand in a net 3' to 5' direction. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork.
GONUTS GO:0006273 Wiki Page

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006273:
Relationship To GO:0006273 Child Term Child Term Name
Part of GO:0033567 DNA replication, Okazaki fragment processing
Has part GO:0006269 DNA replication, synthesis of RNA primer

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0006273. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0006273 based on the entire annotation set Co-occurrence statistics for GO:0006273 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-05-25 Added RELATION is a GO:0016070 (RNA metabolic process)
2008-05-13 Added DEFINITION The synthesis of DNA from a template strand in a net 3' to 5' direction. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork.
2008-05-12 Deleted DEFINITION The synthesis of DNA from a template strand in a net 3' to 5' direction. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork.
2008-04-01 Updated RELATION is a GO:0006271 (DNA strand elongation involved in DNA replication)
2004-04-24 Added DEFINITION The synthesis of DNA from a template strand in a net 3' to 5' direction. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork.
2002-02-06 Updated TERM lagging strand elongation
2001-04-03 Updated TERM lagging strand elongation
2001-03-30 Added TERM lagging strand elongation

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM lagging strand elongation
2001-04-03 Updated TERM lagging strand elongation
2001-03-30 Added TERM lagging strand elongation

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION The synthesis of DNA from a template strand in a net 3' to 5' direction. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork.
2008-05-12 Deleted DEFINITION The synthesis of DNA from a template strand in a net 3' to 5' direction. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork.
2004-04-24 Added DEFINITION The synthesis of DNA from a template strand in a net 3' to 5' direction. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork.

Relationships

Timestamp Action Category Detail
2014-05-25 Added RELATION is a GO:0016070 (RNA metabolic process)
2008-04-01 Updated RELATION is a GO:0006271 (DNA strand elongation involved in DNA replication)
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