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GO:0006098 pentose-phosphate shunt

The process by which glucose is oxidized, coupled to NADPH synthesis. Glucose 6-P is oxidized with the formation of carbon dioxide (CO2), ribulose 5-phosphate and reduced NADP; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses.

Term Information

ID GO:0006098
Name pentose-phosphate shunt
Ontology Biological Process
Definition The process by which glucose is oxidized, coupled to NADPH synthesis. Glucose 6-P is oxidized with the formation of carbon dioxide (CO2), ribulose 5-phosphate and reduced NADP; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses.
Comment

Synonyms

Type Synonym
exact pentose-phosphate pathway
exact hexose monophosphate pathway
exact pentose phosphate pathway
exact pentose phosphate shunt

Cross-references associated with this term:

Database ID
INTERPRO IPR018115
INTERPRO IPR014634
INTERPRO IPR006114
INTERPRO IPR006115
INTERPRO IPR006113
INTERPRO IPR004730
INTERPRO IPR004732
MetaCyc PENTOSE-P-PWY
Wikipedia Pentose_phosphate_pathway
INTERPRO IPR006183
INTERPRO IPR006184
INTERPRO IPR005900
INTERPRO IPR004785

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Ancestor Chart

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0044238 primary metabolic process
GO:0043170 macromolecule metabolic process
GO:0006066 alcohol metabolic process
GO:0009056 catabolic process
GO:0019748 secondary metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0044237 cellular metabolic process
GO:0005975 carbohydrate metabolic process
GO:0006766 vitamin metabolic process
GO:0009820 alkaloid metabolic process
GO:0009057 macromolecule catabolic process
GO:0051186 cofactor metabolic process
GO:0046164 alcohol catabolic process
GO:0044248 cellular catabolic process
GO:0006732 coenzyme metabolic process
GO:0044260 cellular macromolecule metabolic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0016052 carbohydrate catabolic process
GO:0006767 water-soluble vitamin metabolic process
GO:0005996 monosaccharide metabolic process
GO:0006733 oxidoreduction coenzyme metabolic process
GO:0043603 cellular amide metabolic process
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0044262 cellular carbohydrate metabolic process
GO:0019318 hexose metabolic process
GO:0006006 glucose metabolic process
GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
GO:0006753 nucleoside phosphate metabolic process
GO:0009117 nucleotide metabolic process
GO:0046365 monosaccharide catabolic process
GO:0044265 cellular macromolecule catabolic process
GO:0019320 hexose catabolic process
GO:0006007 glucose catabolic process
GO:0019362 pyridine nucleotide metabolic process
GO:0044275 cellular carbohydrate catabolic process
GO:0046496 nicotinamide nucleotide metabolic process
GO:0006769 nicotinamide metabolic process
GO:0006739 NADP metabolic process
GO:0006740 NADPH regeneration
GO:0006098 pentose-phosphate shunt

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
P GO:0009051 pentose-phosphate shunt, oxidative branch
P GO:0009052 pentose-phosphate shunt, non-oxidative branch
R GO:0043456 regulation of pentose-phosphate shunt

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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17ms
Stand-alone
Hostnametomcat-7.ebi.ac.uk
Uptime16:38 12/10/2009
Data version2009-11-20-04-03-08
Terminal
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