spacer

GO:0006097 glyoxylate cycle

Term Information

ID GO:0006097
Name glyoxylate cycle
Ontology Biological Process
Definition A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate.
GONUTS GO:0006097 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact glyoxylate bypass

Cross-references

Database ID
InterPro IPR001465
InterPro IPR006252
InterPro IPR006253
InterPro IPR014273
InterPro IPR019830
MetaCyc GLYOXYLATE-BYPASS
UniProtKB-KW Glyoxylate bypass
Wikipedia Glyoxylate_cycle

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006097:
Relationship To GO:0006097 Child Term Child Term Name
Regulates GO:2000874 regulation of glyoxylate cycle
Negatively regulates GO:2000875 negative regulation of glyoxylate cycle
Positively regulates GO:2000876 positive regulation of glyoxylate cycle
Regulates GO:0035958 regulation of glyoxylate cycle by regulation of transcription from RNA polymerase II promoter
Positively regulates GO:0035959 positive regulation of glyoxylate cycle by positive regulation of transcription from RNA polymerase II promoter

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0006097. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0006097 based on the entire annotation set Co-occurrence statistics for GO:0006097 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-11-28 Added RELATION is a GO:0044723 (single-organism carbohydrate metabolic process)
2010-02-13 Deleted RELATION is a GO:0044281 (small molecule metabolic process)
2010-01-31 Added RELATION is a GO:0044281 (small molecule metabolic process)
2009-03-02 Added XREF Wikipedia:Glyoxylate_cycle
2008-05-13 Added DEFINITION A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate.
2008-05-12 Deleted DEFINITION A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate.
2008-04-01 Updated RELATION is a GO:0044262 (cellular carbohydrate metabolic process)
2008-04-01 Updated RELATION is a GO:0046487 (glyoxylate metabolic process)
2007-08-09 Added SYNONYM glyoxylate bypass
2007-08-09 Deleted SYNONYM glyoxylate bypass
2004-04-19 Added SYNONYM glyoxylate bypass
2004-04-16 Deleted SYNONYM glyoxylate bypass
2003-10-27 Added SYNONYM glyoxylate bypass
2003-10-27 Added XREF MetaCyc:GLYOXYLATE-BYPASS
2003-03-19 Deleted SYNONYM glyoxylate bypass
2002-11-27 Updated DEFINITION A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate.
2002-02-06 Updated TERM glyoxylate cycle
2001-08-06 Added DEFINITION A modified tricarboxylic acid cycle in some plants and microorganisms in which isocitrate, instead of being dehyrogenated, is cleaved by isocitrate lyase to glycoxylate and succinate. This serves to generate glycoxylate from the acetyl moiety of acetyl-CoA. The glyoxylate can then react with another molecule of acetyl-CoA to form malate (catalyzed by malate synthase). These two reactions taken together allow a four-carbon molecule, malate, and hence carbohydrate, to be formed from acetyl-CoA, which, in turn, may be formed from fatty acids. In some plants the enzymes of the glyoxylate cycle are present in glyoxisomes.
2001-04-03 Updated TERM glyoxylate cycle
2001-03-30 Added SYNONYM glyoxylate bypass
2001-03-30 Added TERM glyoxylate cycle

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM glyoxylate cycle
2001-04-03 Updated TERM glyoxylate cycle
2001-03-30 Added TERM glyoxylate cycle

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate.
2008-05-12 Deleted DEFINITION A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate.
2007-08-09 Added SYNONYM glyoxylate bypass
2007-08-09 Deleted SYNONYM glyoxylate bypass
2004-04-19 Added SYNONYM glyoxylate bypass
2004-04-16 Deleted SYNONYM glyoxylate bypass
2003-10-27 Added SYNONYM glyoxylate bypass
2003-03-19 Deleted SYNONYM glyoxylate bypass
2002-11-27 Updated DEFINITION A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate.
2001-08-06 Added DEFINITION A modified tricarboxylic acid cycle in some plants and microorganisms in which isocitrate, instead of being dehyrogenated, is cleaved by isocitrate lyase to glycoxylate and succinate. This serves to generate glycoxylate from the acetyl moiety of acetyl-CoA. The glyoxylate can then react with another molecule of acetyl-CoA to form malate (catalyzed by malate synthase). These two reactions taken together allow a four-carbon molecule, malate, and hence carbohydrate, to be formed from acetyl-CoA, which, in turn, may be formed from fatty acids. In some plants the enzymes of the glyoxylate cycle are present in glyoxisomes.
2001-03-30 Added SYNONYM glyoxylate bypass

Relationships

Timestamp Action Category Detail
2013-11-28 Added RELATION is a GO:0044723 (single-organism carbohydrate metabolic process)
2010-02-13 Deleted RELATION is a GO:0044281 (small molecule metabolic process)
2010-01-31 Added RELATION is a GO:0044281 (small molecule metabolic process)
2008-04-01 Updated RELATION is a GO:0044262 (cellular carbohydrate metabolic process)
2008-04-01 Updated RELATION is a GO:0046487 (glyoxylate metabolic process)

Cross-references

Timestamp Action Category Detail
2009-03-02 Added XREF Wikipedia:Glyoxylate_cycle
2003-10-27 Added XREF MetaCyc:GLYOXYLATE-BYPASS
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
11ms