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GO:0005951 carbamoyl-phosphate synthase complex

Term Information

ID GO:0005951
Name carbamoyl-phosphate synthase complex
Ontology Cellular Component
Definition A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia group cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.
PMID:8626695
Comment Note that in higher eukaryotes, carbamoyl-phosphate synthase is usually a single polypeptide, not a complex, and should therefore not be annotated to this component term.
GONUTS GO:0005951 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow carbamoyl-phosphate synthase arginine-specific complex
narrow arginine-specific carbamoyl phosphate synthetase complex
exact carbamoyl phosphate synthase complex

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

Protein complexes

Database ID Name
IntAct cps_ecoli Carbamoyl phosphate synthetase complex
IntAct cps_yeast carbamoyl-phosphate synthase arginine-specific

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005951:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005951. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005951 based on the entire annotation set Co-occurrence statistics for GO:0005951 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2015-06-18 Added RELATION capable of GO:0004088 (carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity)
2013-11-15 Added RELATION is a GO:1902494 (catalytic complex)
2013-11-15 Deleted RELATION is a GO:0043234 (protein complex)
2010-10-11 Deleted DEFINITION A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia moiety cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.
2010-10-11 Added DEFINITION A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia group cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.
2008-05-13 Added DEFINITION A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia moiety cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.
2008-05-12 Deleted DEFINITION A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia moiety cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.
2008-04-01 Updated RELATION is a GO:0044444 (cytoplasmic part)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2007-08-09 Added SYNONYM arginine-specific carbamoyl phosphate synthetase complex
2007-08-09 Added SYNONYM carbamoyl phosphate synthase complex
2007-08-09 Added SYNONYM carbamoyl-phosphate synthase arginine-specific complex
2007-08-09 Deleted SYNONYM arginine-specific carbamoyl phosphate synthetase complex
2007-08-09 Deleted SYNONYM carbamoyl phosphate synthase complex
2007-08-09 Deleted SYNONYM carbamoyl-phosphate synthase arginine-specific complex
2007-05-27 Updated DEFINITION A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia moiety cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.
2007-05-05 Added SYNONYM carbamoyl-phosphate synthase arginine-specific complex
2007-05-05 Added SYNONYM arginine-specific carbamoyl phosphate synthetase complex
2007-05-05 Added SYNONYM carbamoyl phosphate synthase complex
2003-10-23 Updated DEFINITION An enzyme complex that exists in monomer, dimer, and higher oligomeric forms. Catalysis of the reaction: 2 ATP + L-glutamine + carbon dioxide (CO2) + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate.
2002-11-27 Added DEFINITION An enzyme complex that exists in monomer, dimer, and higher oligomeric forms. Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate.
2002-06-23 Updated TERM carbamoyl-phosphate synthase complex
2002-06-12 Updated TERM carbamoyl-phosphate synthase complex (glutamine-hydrolyzing)
2002-02-06 Updated TERM carbamoyl-phosphate synthase (glutamine-hydrolyzing)
2001-04-03 Updated TERM carbamoyl-phosphate synthase (glutamine-hydrolyzing)
2001-03-30 Added TERM carbamoyl-phosphate synthase (glutamine-hydrolyzing)

Term

Timestamp Action Category Detail
2002-06-23 Updated TERM carbamoyl-phosphate synthase complex
2002-06-12 Updated TERM carbamoyl-phosphate synthase complex (glutamine-hydrolyzing)
2002-02-06 Updated TERM carbamoyl-phosphate synthase (glutamine-hydrolyzing)
2001-04-03 Updated TERM carbamoyl-phosphate synthase (glutamine-hydrolyzing)
2001-03-30 Added TERM carbamoyl-phosphate synthase (glutamine-hydrolyzing)

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia moiety cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.
2010-10-11 Added DEFINITION A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia group cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.
2008-05-13 Added DEFINITION A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia moiety cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.
2008-05-12 Deleted DEFINITION A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia moiety cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.
2007-08-09 Added SYNONYM arginine-specific carbamoyl phosphate synthetase complex
2007-08-09 Added SYNONYM carbamoyl phosphate synthase complex
2007-08-09 Added SYNONYM carbamoyl-phosphate synthase arginine-specific complex
2007-08-09 Deleted SYNONYM arginine-specific carbamoyl phosphate synthetase complex
2007-08-09 Deleted SYNONYM carbamoyl phosphate synthase complex
2007-08-09 Deleted SYNONYM carbamoyl-phosphate synthase arginine-specific complex
2007-05-27 Updated DEFINITION A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia moiety cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.
2007-05-05 Added SYNONYM carbamoyl-phosphate synthase arginine-specific complex
2007-05-05 Added SYNONYM arginine-specific carbamoyl phosphate synthetase complex
2007-05-05 Added SYNONYM carbamoyl phosphate synthase complex
2003-10-23 Updated DEFINITION An enzyme complex that exists in monomer, dimer, and higher oligomeric forms. Catalysis of the reaction: 2 ATP + L-glutamine + carbon dioxide (CO2) + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate.
2002-11-27 Added DEFINITION An enzyme complex that exists in monomer, dimer, and higher oligomeric forms. Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate.

Relationships

Timestamp Action Category Detail
2015-06-18 Added RELATION capable of GO:0004088 (carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity)
2013-11-15 Added RELATION is a GO:1902494 (catalytic complex)
2013-11-15 Deleted RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION is a GO:0044444 (cytoplasmic part)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
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