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GO:0005921 gap junction

Term Information

ID GO:0005921
Name gap junction
Ontology Cellular Component
Definition A cell-cell junction that is composed of an array of small channels that permit small molecules to pass from one cell to another. At gap junctions, the membranes of two adjacent cells are separated by a uniform narrow gap of about 2-4 nm that is spanned by channel-forming proteins called connexins, which form hexagonal tubes called connexons.
GONUTS GO:0005921 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact zonula communicans
related electrical synapse
exact communicating junction
exact macula communicans
related intercellular gap junction channel
related electrotonic synapse
exact gap junction macula
exact gap junction plaque

Cross-references

Database ID
InterPro IPR000990
InterPro IPR002262
NIF_Subcellular sao118541872
UniProtKB-KW Gap junction
UniProtKB-SubCell Gap junction
Wikipedia Gap_junction

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005921:
Relationship To GO:0005921 Child Term Child Term Name
Part of GO:0005922 connexon complex

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005921. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005921 based on the entire annotation set Co-occurrence statistics for GO:0005921 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-08-07 Added SYNONYM intercellular gap junction channel
2013-02-23 Added SYNONYM electrical synapse
2013-02-23 Added SYNONYM electrotonic synapse
2013-02-22 Added SYNONYM gap junction macula
2013-02-22 Added SYNONYM gap junction plaque
2010-02-04 Added XREF NIF_Subcellular:sao118541872
2009-02-08 Added XREF Wikipedia:Gap_junction
2008-11-28 Deleted DEFINITION A cell-cell junction that is composed of an array of small channels that permit small molecules to pass from one cell to another. At gap junctions, the membranes of two adjacent cells are separated by a uniform narrow gap of about 2P4 nm that is spanned by channel-forming proteins called connexins, which form hexagonal tubes called connexons.
2008-11-28 Added DEFINITION A cell-cell junction that is composed of an array of small channels that permit small molecules to pass from one cell to another. At gap junctions, the membranes of two adjacent cells are separated by a uniform narrow gap of about 2-4 nm that is spanned by channel-forming proteins called connexins, which form hexagonal tubes called connexons.
2008-11-27 Deleted DEFINITION Any specialized areas of the plasma membranes of adjacent cells where the membranes are 2-4 nm apart and penetrated by a connexon. This gap junction allows passage of small molecules and electric current. The variety in the properties of gap junctions is reflected in the number of connexins, the family of proteins which form the junction.
2008-11-27 Added DEFINITION A cell-cell junction that is composed of an array of small channels that permit small molecules to pass from one cell to another. At gap junctions, the membranes of two adjacent cells are separated by a uniform narrow gap of about 2P4 nm that is spanned by channel-forming proteins called connexins, which form hexagonal tubes called connexons.
2008-11-27 Deleted RELATION part of GO:0014704 (intercalated disc)
2008-05-13 Added DEFINITION Any specialized areas of the plasma membranes of adjacent cells where the membranes are 2-4 nm apart and penetrated by a connexon. This gap junction allows passage of small molecules and electric current. The variety in the properties of gap junctions is reflected in the number of connexins, the family of proteins which form the junction.
2008-05-12 Deleted DEFINITION Any specialized areas of the plasma membranes of adjacent cells where the membranes are 2-4 nm apart and penetrated by a connexon. This gap junction allows passage of small molecules and electric current. The variety in the properties of gap junctions is reflected in the number of connexins, the family of proteins which form the junction.
2008-04-01 Updated RELATION is a GO:0005911 (cell-cell junction)
2008-04-01 Updated RELATION part of GO:0014704 (intercalated disc)
2007-11-27 Updated DEFINITION Any specialized areas of the plasma membranes of adjacent cells where the membranes are 2-4 nm apart and penetrated by a connexon. This gap junction allows passage of small molecules and electric current. The variety in the properties of gap junctions is reflected in the number of connexins, the family of proteins which form the junction.
2007-08-09 Added SYNONYM communicating junction
2007-08-09 Added SYNONYM macula communicans
2007-08-09 Added SYNONYM zonula communicans
2007-08-09 Deleted SYNONYM communicating junction
2007-08-09 Deleted SYNONYM macula communicans
2007-08-09 Deleted SYNONYM zonula communicans
2004-04-19 Added SYNONYM communicating junction
2004-04-19 Added SYNONYM macula communicans
2004-04-19 Added SYNONYM zonula communicans
2004-04-16 Deleted SYNONYM communicating junction
2004-04-16 Deleted SYNONYM macula communicans
2004-04-16 Deleted SYNONYM zonula communicans
2002-11-27 Updated DEFINITION Any specialized areas of the plasma membranes of adjacent cells where the membranes are 2-4 nm apart and penetrated by a connexon.
2002-02-06 Updated TERM gap junction
2001-08-06 Added DEFINITION ny specialised areas of the plasma membranes of adjacent cells where the membranes are 2-4nm apart and penetrated by a connexon.
2001-04-03 Updated TERM gap junction
2001-03-30 Added SYNONYM communicating junction
2001-03-30 Added SYNONYM macula communicans
2001-03-30 Added SYNONYM zonula communicans
2001-03-30 Added TERM gap junction

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM gap junction
2001-04-03 Updated TERM gap junction
2001-03-30 Added TERM gap junction

Definition/synonyms

Timestamp Action Category Detail
2014-08-07 Added SYNONYM intercellular gap junction channel
2013-02-23 Added SYNONYM electrical synapse
2013-02-23 Added SYNONYM electrotonic synapse
2013-02-22 Added SYNONYM gap junction macula
2013-02-22 Added SYNONYM gap junction plaque
2008-11-28 Deleted DEFINITION A cell-cell junction that is composed of an array of small channels that permit small molecules to pass from one cell to another. At gap junctions, the membranes of two adjacent cells are separated by a uniform narrow gap of about 2P4 nm that is spanned by channel-forming proteins called connexins, which form hexagonal tubes called connexons.
2008-11-28 Added DEFINITION A cell-cell junction that is composed of an array of small channels that permit small molecules to pass from one cell to another. At gap junctions, the membranes of two adjacent cells are separated by a uniform narrow gap of about 2-4 nm that is spanned by channel-forming proteins called connexins, which form hexagonal tubes called connexons.
2008-11-27 Deleted DEFINITION Any specialized areas of the plasma membranes of adjacent cells where the membranes are 2-4 nm apart and penetrated by a connexon. This gap junction allows passage of small molecules and electric current. The variety in the properties of gap junctions is reflected in the number of connexins, the family of proteins which form the junction.
2008-11-27 Added DEFINITION A cell-cell junction that is composed of an array of small channels that permit small molecules to pass from one cell to another. At gap junctions, the membranes of two adjacent cells are separated by a uniform narrow gap of about 2P4 nm that is spanned by channel-forming proteins called connexins, which form hexagonal tubes called connexons.
2008-05-13 Added DEFINITION Any specialized areas of the plasma membranes of adjacent cells where the membranes are 2-4 nm apart and penetrated by a connexon. This gap junction allows passage of small molecules and electric current. The variety in the properties of gap junctions is reflected in the number of connexins, the family of proteins which form the junction.
2008-05-12 Deleted DEFINITION Any specialized areas of the plasma membranes of adjacent cells where the membranes are 2-4 nm apart and penetrated by a connexon. This gap junction allows passage of small molecules and electric current. The variety in the properties of gap junctions is reflected in the number of connexins, the family of proteins which form the junction.
2007-11-27 Updated DEFINITION Any specialized areas of the plasma membranes of adjacent cells where the membranes are 2-4 nm apart and penetrated by a connexon. This gap junction allows passage of small molecules and electric current. The variety in the properties of gap junctions is reflected in the number of connexins, the family of proteins which form the junction.
2007-08-09 Added SYNONYM communicating junction
2007-08-09 Added SYNONYM macula communicans
2007-08-09 Added SYNONYM zonula communicans
2007-08-09 Deleted SYNONYM communicating junction
2007-08-09 Deleted SYNONYM macula communicans
2007-08-09 Deleted SYNONYM zonula communicans
2004-04-19 Added SYNONYM communicating junction
2004-04-19 Added SYNONYM macula communicans
2004-04-19 Added SYNONYM zonula communicans
2004-04-16 Deleted SYNONYM communicating junction
2004-04-16 Deleted SYNONYM macula communicans
2004-04-16 Deleted SYNONYM zonula communicans
2002-11-27 Updated DEFINITION Any specialized areas of the plasma membranes of adjacent cells where the membranes are 2-4 nm apart and penetrated by a connexon.
2001-08-06 Added DEFINITION ny specialised areas of the plasma membranes of adjacent cells where the membranes are 2-4nm apart and penetrated by a connexon.
2001-03-30 Added SYNONYM communicating junction
2001-03-30 Added SYNONYM macula communicans
2001-03-30 Added SYNONYM zonula communicans

Relationships

Timestamp Action Category Detail
2008-11-27 Deleted RELATION part of GO:0014704 (intercalated disc)
2008-04-01 Updated RELATION is a GO:0005911 (cell-cell junction)
2008-04-01 Updated RELATION part of GO:0014704 (intercalated disc)

Cross-references

Timestamp Action Category Detail
2010-02-04 Added XREF NIF_Subcellular:sao118541872
2009-02-08 Added XREF Wikipedia:Gap_junction
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