spacer

GO:0005889 hydrogen:potassium-exchanging ATPase complex

Term Information

ID GO:0005889
Name hydrogen:potassium-exchanging ATPase complex
Ontology Cellular Component
Definition A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present.
PMID:11756431
GONUTS GO:0005889 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact hydrogen/potassium-exchanging ATPase complex
broad proton pump

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005889:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005889. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005889 based on the entire annotation set Co-occurrence statistics for GO:0005889 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-05-04 Deleted DEFINITION A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of Na+ and K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present.
2014-05-04 Added DEFINITION A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present.
2013-08-15 Deleted RELATION is a GO:0043234 (protein complex)
2013-08-15 Added RELATION is a GO:0090533 (cation-transporting ATPase complex)
2008-05-13 Added DEFINITION A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of Na+ and K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present.
2008-05-12 Deleted DEFINITION A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of Na+ and K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present.
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION part of GO:0005887 (integral component of plasma membrane)
2008-04-01 Updated RELATION is a GO:0044459 (plasma membrane part)
2007-08-09 Added SYNONYM hydrogen/potassium-exchanging ATPase complex
2007-08-09 Added SYNONYM proton pump
2007-08-09 Deleted SYNONYM hydrogen/potassium-exchanging ATPase complex
2007-08-09 Deleted SYNONYM proton pump
2007-04-20 Added DEFINITION A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of Na+ and K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present.
2004-07-26 Added SYNONYM hydrogen/potassium-exchanging ATPase complex
2004-07-26 Updated TERM hydrogen:potassium-exchanging ATPase complex
2004-04-19 Added SYNONYM proton pump
2004-04-16 Deleted SYNONYM proton pump
2002-07-23 Updated TERM hydrogen/potassium-exchanging ATPase complex
2002-02-06 Updated TERM hydrogen/potassium-exchanging ATPase
2001-04-03 Updated TERM hydrogen/potassium-exchanging ATPase
2001-03-30 Added SYNONYM proton pump
2001-03-30 Added TERM hydrogen/potassium-exchanging ATPase

Term

Timestamp Action Category Detail
2004-07-26 Updated TERM hydrogen:potassium-exchanging ATPase complex
2002-07-23 Updated TERM hydrogen/potassium-exchanging ATPase complex
2002-02-06 Updated TERM hydrogen/potassium-exchanging ATPase
2001-04-03 Updated TERM hydrogen/potassium-exchanging ATPase
2001-03-30 Added TERM hydrogen/potassium-exchanging ATPase

Definition/synonyms

Timestamp Action Category Detail
2014-05-04 Deleted DEFINITION A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of Na+ and K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present.
2014-05-04 Added DEFINITION A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present.
2008-05-13 Added DEFINITION A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of Na+ and K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present.
2008-05-12 Deleted DEFINITION A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of Na+ and K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present.
2007-08-09 Added SYNONYM hydrogen/potassium-exchanging ATPase complex
2007-08-09 Added SYNONYM proton pump
2007-08-09 Deleted SYNONYM hydrogen/potassium-exchanging ATPase complex
2007-08-09 Deleted SYNONYM proton pump
2007-04-20 Added DEFINITION A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of Na+ and K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present.
2004-07-26 Added SYNONYM hydrogen/potassium-exchanging ATPase complex
2004-04-19 Added SYNONYM proton pump
2004-04-16 Deleted SYNONYM proton pump
2001-03-30 Added SYNONYM proton pump

Relationships

Timestamp Action Category Detail
2013-08-15 Deleted RELATION is a GO:0043234 (protein complex)
2013-08-15 Added RELATION is a GO:0090533 (cation-transporting ATPase complex)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION part of GO:0005887 (integral component of plasma membrane)
2008-04-01 Updated RELATION is a GO:0044459 (plasma membrane part)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
12ms