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GO:0005887 integral component of plasma membrane

Term Information

ID GO:0005887
Name integral component of plasma membrane
Ontology Cellular Component
Definition The component of the plasma membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. This component includes gene products that are buried in the bilayer with no exposure outside the bilayer.
GONUTS GO:0005887 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow integral to plasma membrane

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR000377
InterPro IPR000450
InterPro IPR000455
InterPro IPR000497
InterPro IPR000502
InterPro IPR000505
InterPro IPR000610
InterPro IPR000929
InterPro IPR000995
InterPro IPR001183
InterPro IPR001413
InterPro IPR001432
InterPro IPR001520
InterPro IPR001620
InterPro IPR002147
InterPro IPR002185
InterPro IPR002228
InterPro IPR002231
InterPro IPR002434
InterPro IPR002435
InterPro IPR002436
InterPro IPR002438
InterPro IPR002980
InterPro IPR002981
InterPro IPR002982
InterPro IPR002983
InterPro IPR002984
InterPro IPR003028
InterPro IPR003804
InterPro IPR004626
InterPro IPR005672
InterPro IPR005769
InterPro IPR005951
InterPro IPR005989
InterPro IPR008127
InterPro IPR009134
InterPro IPR009135
InterPro IPR009137
InterPro IPR012256
InterPro IPR013059
InterPro IPR013086
InterPro IPR014083
InterPro IPR016257
InterPro IPR017324
InterPro IPR017329
InterPro IPR018397
InterPro IPR018941
InterPro IPR020446
InterPro IPR020455
InterPro IPR020461
InterPro IPR020766
InterPro IPR020777
InterPro IPR020912
InterPro IPR022317
InterPro IPR022318
InterPro IPR022319
InterPro IPR022461
InterPro IPR023777
InterPro IPR023861
InterPro IPR023941
InterPro IPR027425
InterPro IPR027690
InterPro IPR027691
InterPro IPR028339
InterPro IPR028371
InterPro IPR028509
InterPro IPR028515
InterPro IPR028684
InterPro IPR028715
InterPro IPR028723
InterPro IPR028729
InterPro IPR028792
InterPro IPR029553
InterPro IPR029566
InterPro IPR029575
InterPro IPR029870

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0005108 transmembrane ephrin CONSIDER GO:0005887
GO:0005888 proteoglycan integral to plasma membrane REPLACEDBY GO:0005887

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005887:
Relationship To GO:0005887 Child Term Child Term Name
Part of GO:0016935 glycine-gated chloride channel complex
Part of GO:0030988 high molecular weight kininogen receptor complex
Part of GO:0000222 plasma membrane proton-transporting V-type ATPase, V0 domain
Part of GO:0000223 plasma membrane proton-transporting V-type ATPase, V1 domain
Part of GO:0001518 voltage-gated sodium channel complex
Part of GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex
Part of GO:0045323 interleukin-1 receptor complex
Part of GO:0042022 interleukin-12 receptor complex
Part of GO:0043020 NADPH oxidase complex
Part of GO:0048179 activin receptor complex
Part of GO:0005579 membrane attack complex
Part of GO:0008076 voltage-gated potassium channel complex
Part of GO:0008282 ATP-sensitive potassium channel complex
Part of GO:0019183 histamine-gated chloride channel complex
Part of GO:0070110 ciliary neurotrophic factor receptor complex
Part of GO:0030876 interleukin-20 receptor complex
Part of GO:0045092 interleukin-18 receptor complex
Part of GO:0008305 integrin complex
Part of GO:0008328 ionotropic glutamate receptor complex
Part of GO:0043384 pre-T cell receptor complex
Part of GO:0016516 interleukin-4 receptor complex
Part of GO:0005889 hydrogen:potassium-exchanging ATPase complex
Part of GO:0005890 sodium:potassium-exchanging ATPase complex
Part of GO:0005892 acetylcholine-gated channel complex
Part of GO:0005893 interleukin-2 receptor complex
Part of GO:0005894 interleukin-3 receptor complex
Part of GO:0005895 interleukin-5 receptor complex
Part of GO:0005896 interleukin-6 receptor complex
Part of GO:0005897 interleukin-9 receptor complex
Part of GO:0005898 interleukin-13 receptor complex
Part of GO:0005899 insulin receptor complex
Part of GO:0005900 oncostatin-M receptor complex
Part of GO:0032002 interleukin-28 receptor complex
Part of GO:1990154 enzyme IIA-maltose transporter complex
Part of GO:0034995 SC5b-7 complex
Part of GO:0034997 alphav-beta5 integrin-vitronectin complex
Part of GO:0070014 sucrase-isomaltase complex
Part of GO:0070022 transforming growth factor beta receptor homodimeric complex
Part of GO:0035631 CD40 receptor complex
Is a GO:0071575 integral component of external side of plasma membrane
Part of GO:0070724 BMP receptor complex
Part of GO:1990406 CGRP receptor complex
Part of GO:0030937 collagen type XVII trimer
Part of GO:1990060 maltose transport complex
Part of GO:1990270 platelet-derived growth factor receptor-ligand complex
Part of GO:1990398 Cus cation efflux complex
Part of GO:1990207 EmrE multidrug transporter complex
Part of GO:0072536 interleukin-23 receptor complex
Is a GO:0061455 integral component of muscle cell projection membrane
Part of GO:0038197 type I interferon receptor complex
Part of GO:0005600 collagen type XIII trimer
Part of GO:1990322 collagen type XXIII trimer
Part of GO:1990327 collagen type XXV trimer
Part of GO:0030936 transmembrane collagen trimer
Part of GO:1990392 EFF-1 complex

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005887. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005887 based on the entire annotation set Co-occurrence statistics for GO:0005887 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-01-16 Added RELATION is a GO:0044459 (plasma membrane part)
2013-12-21 Updated TERM integral component of plasma membrane
2013-12-21 Added DEFINITION The component of the plasma membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. This component includes gene products that are buried in the bilayer with no exposure outside the bilayer.
2013-12-21 Deleted DEFINITION Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
2013-12-21 Added SYNONYM integral to plasma membrane
2013-12-21 Added RELATION part of GO:0031226 (intrinsic component of plasma membrane)
2013-12-21 Deleted RELATION is a GO:0031226 (intrinsic component of plasma membrane)
2008-05-13 Added DEFINITION Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
2008-05-12 Deleted DEFINITION Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
2008-04-01 Updated RELATION is a GO:0016021 (integral component of membrane)
2008-04-01 Updated RELATION is a GO:0031226 (intrinsic component of plasma membrane)
2007-10-16 Deleted SYNONYM proteoglycan integral to plasma membrane
2007-10-05 Deleted SYNONYM transmembrane ephrin
2007-08-09 Added SYNONYM proteoglycan integral to plasma membrane
2007-08-09 Added SYNONYM transmembrane ephrin
2007-08-09 Deleted SYNONYM proteoglycan integral to plasma membrane
2007-08-09 Deleted SYNONYM transmembrane ephrin
2005-11-12 Updated DEFINITION Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
2005-08-10 Added SYNONYM proteoglycan integral to plasma membrane
2005-08-10 Added SYNONYM transmembrane ephrin
2003-03-26 Updated DEFINITION Penetrating at least one phospholipid bilayer of a plasma membrane. Also refers to the state of being buried in the bilayer with no exposure outside the bilayer.
2002-12-17 Updated TERM integral to plasma membrane
2002-11-27 Added DEFINITION An integral membrane protein found in the plasma membrane; cannot be dissociated from the plasma membrane except by drastic treatment with a reagent such as a detergent, protein denaturant or organic solvent; has one or more transmembrane domains.
2002-02-06 Updated TERM integral plasma membrane protein
2001-04-03 Updated TERM integral plasma membrane protein
2001-03-30 Added TERM integral plasma membrane protein

Term

Timestamp Action Category Detail
2013-12-21 Updated TERM integral component of plasma membrane
2002-12-17 Updated TERM integral to plasma membrane
2002-02-06 Updated TERM integral plasma membrane protein
2001-04-03 Updated TERM integral plasma membrane protein
2001-03-30 Added TERM integral plasma membrane protein

Definition/synonyms

Timestamp Action Category Detail
2013-12-21 Added DEFINITION The component of the plasma membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. This component includes gene products that are buried in the bilayer with no exposure outside the bilayer.
2013-12-21 Deleted DEFINITION Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
2013-12-21 Added SYNONYM integral to plasma membrane
2008-05-13 Added DEFINITION Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
2008-05-12 Deleted DEFINITION Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
2007-10-16 Deleted SYNONYM proteoglycan integral to plasma membrane
2007-10-05 Deleted SYNONYM transmembrane ephrin
2007-08-09 Added SYNONYM proteoglycan integral to plasma membrane
2007-08-09 Added SYNONYM transmembrane ephrin
2007-08-09 Deleted SYNONYM proteoglycan integral to plasma membrane
2007-08-09 Deleted SYNONYM transmembrane ephrin
2005-11-12 Updated DEFINITION Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
2005-08-10 Added SYNONYM proteoglycan integral to plasma membrane
2005-08-10 Added SYNONYM transmembrane ephrin
2003-03-26 Updated DEFINITION Penetrating at least one phospholipid bilayer of a plasma membrane. Also refers to the state of being buried in the bilayer with no exposure outside the bilayer.
2002-11-27 Added DEFINITION An integral membrane protein found in the plasma membrane; cannot be dissociated from the plasma membrane except by drastic treatment with a reagent such as a detergent, protein denaturant or organic solvent; has one or more transmembrane domains.

Relationships

Timestamp Action Category Detail
2014-01-16 Added RELATION is a GO:0044459 (plasma membrane part)
2013-12-21 Added RELATION part of GO:0031226 (intrinsic component of plasma membrane)
2013-12-21 Deleted RELATION is a GO:0031226 (intrinsic component of plasma membrane)
2008-04-01 Updated RELATION is a GO:0016021 (integral component of membrane)
2008-04-01 Updated RELATION is a GO:0031226 (intrinsic component of plasma membrane)
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