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GO:0005884 actin filament

Term Information

ID GO:0005884
Name actin filament
Ontology Cellular Component
Definition A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
PMID:10666339
GONUTS GO:0005884 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact microfilament

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

Cross-references

Database ID
FMA 63850
InterPro IPR001265
InterPro IPR027643
NIF_Subcellular sao1588493326
Wikipedia Actin

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005884:
Relationship To GO:0005884 Child Term Child Term Name
Is a GO:0042643 actomyosin, actin portion
Part of GO:0031941 filamentous actin
Is a GO:1903144 actomyosin contractile ring actin filament
Is a GO:1903145 actin filament of cell cortex of cell tip

Protein Annotation

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GO Identifier
GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005884. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005884 based on the entire annotation set Co-occurrence statistics for GO:0005884 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-07-22 Added XREF FMA:63850
2010-02-04 Added XREF NIF_Subcellular:sao1588493326
2009-11-12 Deleted SYNONYM microfilament
2009-11-12 Added SYNONYM microfilament
2009-09-17 Added RELATION is a GO:0043234 (protein complex)
2009-02-08 Added XREF Wikipedia:Actin
2008-05-13 Added DEFINITION A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
2008-05-12 Deleted DEFINITION A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
2008-04-01 Updated RELATION part of GO:0015629 (actin cytoskeleton)
2008-04-01 Updated RELATION is a GO:0044430 (cytoskeletal part)
2007-08-09 Added SYNONYM microfilament
2007-08-09 Deleted SYNONYM microfilament
2005-12-01 Deleted SYNONYM F-actin
2005-11-29 Updated DEFINITION A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
2004-04-19 Added SYNONYM F-actin
2004-04-19 Added SYNONYM microfilament
2004-04-16 Deleted SYNONYM F-actin
2004-04-16 Deleted SYNONYM microfilament
2003-07-16 Added SYNONYM F-actin
2002-11-27 Added DEFINITION A two-stranded helical polymer of the protein actin. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
2002-02-06 Updated TERM actin filament
2001-04-03 Updated TERM actin filament
2001-03-30 Added SYNONYM microfilament
2001-03-30 Added TERM actin filament

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM actin filament
2001-04-03 Updated TERM actin filament
2001-03-30 Added TERM actin filament

Definition/synonyms

Timestamp Action Category Detail
2009-11-12 Deleted SYNONYM microfilament
2009-11-12 Added SYNONYM microfilament
2008-05-13 Added DEFINITION A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
2008-05-12 Deleted DEFINITION A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
2007-08-09 Added SYNONYM microfilament
2007-08-09 Deleted SYNONYM microfilament
2005-12-01 Deleted SYNONYM F-actin
2005-11-29 Updated DEFINITION A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
2004-04-19 Added SYNONYM F-actin
2004-04-19 Added SYNONYM microfilament
2004-04-16 Deleted SYNONYM F-actin
2004-04-16 Deleted SYNONYM microfilament
2003-07-16 Added SYNONYM F-actin
2002-11-27 Added DEFINITION A two-stranded helical polymer of the protein actin. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
2001-03-30 Added SYNONYM microfilament

Relationships

Timestamp Action Category Detail
2009-09-17 Added RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION part of GO:0015629 (actin cytoskeleton)
2008-04-01 Updated RELATION is a GO:0044430 (cytoskeletal part)

Cross-references

Timestamp Action Category Detail
2013-07-22 Added XREF FMA:63850
2010-02-04 Added XREF NIF_Subcellular:sao1588493326
2009-02-08 Added XREF Wikipedia:Actin
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