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GO:0005882 intermediate filament

Term Information

ID GO:0005882
Name intermediate filament
Ontology Cellular Component
Definition A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.
GONUTS GO:0005882 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related type I intermediate filament associated protein
related intermediate filament associated protein
related type II intermediate filament associated protein

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

Cross-references

Database ID
FMA 63851
InterPro IPR001664
InterPro IPR003461
InterPro IPR006821
InterPro IPR027694
InterPro IPR027698
InterPro IPR027699
InterPro IPR027701
InterPro IPR027702
NIF_Subcellular sao952483289
UniProtKB-KW Intermediate filament
UniProtKB-KW Keratin
Wikipedia Intermediate_filament

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0001721 intermediate filament associated protein REPLACEDBY GO:0005882
GO:0001722 type I intermediate filament associated protein REPLACEDBY GO:0005882
GO:0001723 type II intermediate filament associated protein REPLACEDBY GO:0005882

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005882:
Relationship To GO:0005882 Child Term Child Term Name
Is a GO:0005638 lamin filament
Is a GO:0045095 keratin filament
Is a GO:0045098 type III intermediate filament
Is a GO:0005883 neurofilament
Is a GO:0097426 glial filament

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005882. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005882 based on the entire annotation set Co-occurrence statistics for GO:0005882 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-07-22 Added XREF FMA:63851
2010-02-04 Added XREF NIF_Subcellular:sao952483289
2009-09-17 Added RELATION is a GO:0043234 (protein complex)
2009-02-08 Added XREF Wikipedia:Intermediate_filament
2008-10-02 Added DEFINITION A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.
2008-10-02 Deleted DEFINITION A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filamentss; and Type V, lamins.
2008-09-06 Deleted DEFINITION A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filamentss; and Type V, lamins.
2008-09-06 Added DEFINITION A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filamentss; and Type V, lamins.
2008-08-18 Deleted DEFINITION A distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: keratin filaments of mammalian epithelial cells; desmin filaments found in cells of muscles of all types; vimentin filaments found in mesenchymal cells; neurofilaments of neurons; and glial filaments found in all types of glial cells.
2008-08-18 Added DEFINITION A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filamentss; and Type V, lamins.
2008-05-13 Added DEFINITION A distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: keratin filaments of mammalian epithelial cells; desmin filaments found in cells of muscles of all types; vimentin filaments found in mesenchymal cells; neurofilaments of neurons; and glial filaments found in all types of glial cells.
2008-05-12 Deleted DEFINITION A distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: keratin filaments of mammalian epithelial cells; desmin filaments found in cells of muscles of all types; vimentin filaments found in mesenchymal cells; neurofilaments of neurons; and glial filaments found in all types of glial cells.
2008-04-01 Updated RELATION is a GO:0044430 (cytoskeletal part)
2008-04-01 Updated RELATION part of GO:0045111 (intermediate filament cytoskeleton)
2007-08-09 Added SYNONYM intermediate filament associated protein
2007-08-09 Added SYNONYM type I intermediate filament associated protein
2007-08-09 Added SYNONYM type II intermediate filament associated protein
2007-08-09 Deleted SYNONYM intermediate filament associated protein
2007-08-09 Deleted SYNONYM type I intermediate filament associated protein
2007-08-09 Deleted SYNONYM type II intermediate filament associated protein
2007-01-09 Updated DEFINITION A distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: keratin filaments of mammalian epithelial cells; desmin filaments found in cells of muscles of all types; vimentin filaments found in mesenchymal cells; neurofilaments of neurons; and glial filaments found in all types of glial cells.
2005-08-10 Added SYNONYM intermediate filament associated protein
2005-08-10 Added SYNONYM type I intermediate filament associated protein
2005-08-10 Added SYNONYM type II intermediate filament associated protein
2002-11-27 Added DEFINITION A distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: keratin filaments of mammalian epithelial cells; desmin filaments found in cells of muscles of all types; vimentin filaments found in mesenchymal cells; neurofilaments of neurons; and glial filaments found in all types of glial cells.
2002-02-06 Updated TERM intermediate filament
2001-04-03 Updated TERM intermediate filament
2001-03-30 Added TERM intermediate filament

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM intermediate filament
2001-04-03 Updated TERM intermediate filament
2001-03-30 Added TERM intermediate filament

Definition/synonyms

Timestamp Action Category Detail
2008-10-02 Added DEFINITION A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.
2008-10-02 Deleted DEFINITION A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filamentss; and Type V, lamins.
2008-09-06 Deleted DEFINITION A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filamentss; and Type V, lamins.
2008-09-06 Added DEFINITION A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filamentss; and Type V, lamins.
2008-08-18 Deleted DEFINITION A distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: keratin filaments of mammalian epithelial cells; desmin filaments found in cells of muscles of all types; vimentin filaments found in mesenchymal cells; neurofilaments of neurons; and glial filaments found in all types of glial cells.
2008-08-18 Added DEFINITION A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filamentss; and Type V, lamins.
2008-05-13 Added DEFINITION A distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: keratin filaments of mammalian epithelial cells; desmin filaments found in cells of muscles of all types; vimentin filaments found in mesenchymal cells; neurofilaments of neurons; and glial filaments found in all types of glial cells.
2008-05-12 Deleted DEFINITION A distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: keratin filaments of mammalian epithelial cells; desmin filaments found in cells of muscles of all types; vimentin filaments found in mesenchymal cells; neurofilaments of neurons; and glial filaments found in all types of glial cells.
2007-08-09 Added SYNONYM intermediate filament associated protein
2007-08-09 Added SYNONYM type I intermediate filament associated protein
2007-08-09 Added SYNONYM type II intermediate filament associated protein
2007-08-09 Deleted SYNONYM intermediate filament associated protein
2007-08-09 Deleted SYNONYM type I intermediate filament associated protein
2007-08-09 Deleted SYNONYM type II intermediate filament associated protein
2007-01-09 Updated DEFINITION A distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: keratin filaments of mammalian epithelial cells; desmin filaments found in cells of muscles of all types; vimentin filaments found in mesenchymal cells; neurofilaments of neurons; and glial filaments found in all types of glial cells.
2005-08-10 Added SYNONYM intermediate filament associated protein
2005-08-10 Added SYNONYM type I intermediate filament associated protein
2005-08-10 Added SYNONYM type II intermediate filament associated protein
2002-11-27 Added DEFINITION A distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: keratin filaments of mammalian epithelial cells; desmin filaments found in cells of muscles of all types; vimentin filaments found in mesenchymal cells; neurofilaments of neurons; and glial filaments found in all types of glial cells.

Relationships

Timestamp Action Category Detail
2009-09-17 Added RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION is a GO:0044430 (cytoskeletal part)
2008-04-01 Updated RELATION part of GO:0045111 (intermediate filament cytoskeleton)

Cross-references

Timestamp Action Category Detail
2013-07-22 Added XREF FMA:63851
2010-02-04 Added XREF NIF_Subcellular:sao952483289
2009-02-08 Added XREF Wikipedia:Intermediate_filament
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