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GO:0005882 intermediate filament

A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.

Term Information

ID GO:0005882
Name intermediate filament
Ontology Cellular Component
Definition A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.
Comment

Synonyms

Type Synonym
related type II intermediate filament associated protein
related intermediate filament associated protein
related type I intermediate filament associated protein

Cross-references associated with this term:

Database ID
INTERPRO IPR006821
Wikipedia Intermediate_filament
INTERPRO IPR003461

This term can be used instead of these obsolete terms:

GO:0001723 type II intermediate filament associated protein (replaced_by GO:0005882)
GO:0001721 intermediate filament associated protein (replaced_by GO:0005882)
GO:0001722 type I intermediate filament associated protein (replaced_by GO:0005882)

Web service: term information

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Ancestor Chart

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0005575 cellular_component
GO:0032991 macromolecular complex
GO:0043226 organelle
GO:0005623 cell
GO:0043234 protein complex
GO:0044464 cell part
GO:0043228 non-membrane-bounded organelle
GO:0044422 organelle part
GO:0005622 intracellular
GO:0044424 intracellular part
GO:0043229 intracellular organelle
GO:0043232 intracellular non-membrane-bounded organelle
GO:0044446 intracellular organelle part
GO:0005856 cytoskeleton
GO:0045111 intermediate filament cytoskeleton
GO:0044430 cytoskeletal part
GO:0005882 intermediate filament

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0005638 lamin filament
I GO:0045095 keratin filament
I GO:0045098 type III intermediate filament
I GO:0005883 neurofilament

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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