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GO:0005874 microtubule

Term Information

ID GO:0005874
Name microtubule
Ontology Cellular Component
Definition Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
GONUTS GO:0005874 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact microtubuli
narrow neurotubule
exact microtubulus

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR000217
InterPro IPR002452
InterPro IPR002453
InterPro IPR002967
InterPro IPR004226
InterPro IPR007882
InterPro IPR008604
InterPro IPR009675
InterPro IPR015656
InterPro IPR017975
InterPro IPR026074
InterPro IPR026708
InterPro IPR026756
InterPro IPR027188
InterPro IPR027321
InterPro IPR027322
InterPro IPR027326
InterPro IPR027741
InterPro IPR028594
NIF_Subcellular sao1846835077
UniProtKB-KW Microtubule
Wikipedia Microtubule

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005874:
Relationship To GO:0005874 Child Term Child Term Name
Is a GO:0020025 subpellicular microtubule
Is a GO:0005876 spindle microtubule
Is a GO:0005880 nuclear microtubule
Is a GO:0005881 cytoplasmic microtubule
Part of GO:0035371 microtubule plus-end
Is a GO:0033289 intraconoid microtubule
Is a GO:1901588 dendritic microtubule
Is a GO:0097649 A tubule
Is a GO:0097650 B tubule
Part of GO:0036449 microtubule minus-end

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005874. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005874 based on the entire annotation set Co-occurrence statistics for GO:0005874 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-06-19 Added RELATION has part GO:0097545 (axonemal outer doublet)
2014-04-21 Added RELATION has part GO:0005930 (axoneme)
2014-04-06 Added RELATION has part GO:0097596 (ventral disc supernumerary microtubule array)
2014-04-06 Added RELATION has part GO:0097593 (ventral disc microtubule array)
2014-02-13 Added RELATION has part GO:0097568 (median body)
2012-11-09 Added RELATION has part GO:0097427 (microtubule bundle)
2012-11-09 Added SYNONYM neurotubule
2010-08-20 Added SYNONYM microtubuli
2010-08-20 Added SYNONYM microtubulus
2010-02-04 Added XREF NIF_Subcellular:sao1846835077
2009-09-17 Added RELATION is a GO:0043234 (protein complex)
2009-02-08 Added XREF Wikipedia:Microtubule
2008-05-13 Added DEFINITION Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
2008-05-12 Deleted DEFINITION Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
2008-04-01 Updated RELATION part of GO:0015630 (microtubule cytoskeleton)
2008-04-01 Updated RELATION is a GO:0044430 (cytoskeletal part)
2004-03-13 Updated DEFINITION Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
2003-10-18 Updated DEFINITION Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, eg. in the spindle.
2003-04-24 Updated DEFINITION Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e. g. in the spindle.
2002-11-27 Updated DEFINITION Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
2002-02-06 Updated TERM microtubule
2001-08-06 Added DEFINITION Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubilin monomers are arranged in a helical pattern on the microtubular surface, and with the &agr;/&bgr; axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
2001-04-03 Updated TERM microtubule
2001-03-30 Added TERM microtubule

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM microtubule
2001-04-03 Updated TERM microtubule
2001-03-30 Added TERM microtubule

Definition/synonyms

Timestamp Action Category Detail
2012-11-09 Added SYNONYM neurotubule
2010-08-20 Added SYNONYM microtubuli
2010-08-20 Added SYNONYM microtubulus
2008-05-13 Added DEFINITION Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
2008-05-12 Deleted DEFINITION Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
2004-03-13 Updated DEFINITION Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
2003-10-18 Updated DEFINITION Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, eg. in the spindle.
2003-04-24 Updated DEFINITION Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e. g. in the spindle.
2002-11-27 Updated DEFINITION Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
2001-08-06 Added DEFINITION Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubilin monomers are arranged in a helical pattern on the microtubular surface, and with the &agr;/&bgr; axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.

Relationships

Timestamp Action Category Detail
2014-06-19 Added RELATION has part GO:0097545 (axonemal outer doublet)
2014-04-21 Added RELATION has part GO:0005930 (axoneme)
2014-04-06 Added RELATION has part GO:0097596 (ventral disc supernumerary microtubule array)
2014-04-06 Added RELATION has part GO:0097593 (ventral disc microtubule array)
2014-02-13 Added RELATION has part GO:0097568 (median body)
2012-11-09 Added RELATION has part GO:0097427 (microtubule bundle)
2009-09-17 Added RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION part of GO:0015630 (microtubule cytoskeleton)
2008-04-01 Updated RELATION is a GO:0044430 (cytoskeletal part)

Cross-references

Timestamp Action Category Detail
2010-02-04 Added XREF NIF_Subcellular:sao1846835077
2009-02-08 Added XREF Wikipedia:Microtubule
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