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GO:0005847 mRNA cleavage and polyadenylation specificity factor complex

A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.

Term Information

ID GO:0005847
Name mRNA cleavage and polyadenylation specificity factor complex
Ontology Cellular Component
Definition A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
Comment

Synonyms

Type Synonym
narrow CPF complex
narrow CPSF complex
related cleavage and polyadenylylation specificity factor activity
related CFII complex

This term can be used instead of these obsolete terms:

GO:0030364 cleavage and polyadenylylation specificity factor activity (replaced_by GO:0005847)

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Ancestor Chart

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Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0005575 cellular_component
GO:0005623 cell
GO:0043226 organelle
GO:0032991 macromolecular complex
GO:0031974 membrane-enclosed lumen
GO:0043234 protein complex
GO:0044422 organelle part
GO:0043227 membrane-bounded organelle
GO:0044464 cell part
GO:0005622 intracellular
GO:0044424 intracellular part
GO:0043233 organelle lumen
GO:0043229 intracellular organelle
GO:0044446 intracellular organelle part
GO:0043231 intracellular membrane-bounded organelle
GO:0005634 nucleus
GO:0070013 intracellular organelle lumen
GO:0044428 nuclear part
GO:0031981 nuclear lumen
GO:0005654 nucleoplasm
GO:0044451 nucleoplasm part
GO:0005849 mRNA cleavage factor complex
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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