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GO:0005839 proteasome core complex

Term Information

ID GO:0005839
Name proteasome core complex
Ontology Cellular Component
Definition A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex.
PMID:10806206
Secondary IDs GO:0000503
GONUTS GO:0005839 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow 20S core complex
exact macropain
narrow 20S proteasome
narrow PA28gamma-20S proteasome

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR000243
InterPro IPR001353
InterPro IPR016050
InterPro IPR019982
InterPro IPR019983
InterPro IPR022483

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005839:
Relationship To GO:0005839 Child Term Child Term Name
Is a GO:0031601 nuclear proteasome core complex
Is a GO:0031602 ER proteasome core complex
Is a GO:0031603 cytosolic proteasome core complex
Part of GO:0019773 proteasome core complex, alpha-subunit complex
Part of GO:0019774 proteasome core complex, beta-subunit complex

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
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Taxon
Date
Assigned By
Product Form ID
Name
Synonym
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005839. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005839 based on the entire annotation set Co-occurrence statistics for GO:0005839 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2009-12-06 Added SYNONYM 20S proteasome
2009-07-11 Deleted SYNONYM proteasome core complex (sensu Eukaryota)
2009-07-11 Deleted SYNONYM proteasome core complex (sensu Bacteria)
2009-02-25 Deleted SYNONYM 26S proteasome
2009-02-25 Added SYNONYM PA28gamma-20S proteasome
2008-07-28 Added RELATION is a GO:0044424 (intracellular part)
2008-07-28 Deleted RELATION is a GO:0044445 (cytosolic part)
2008-05-13 Added DEFINITION A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex.
2008-05-12 Deleted DEFINITION A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex.
2008-04-01 Updated RELATION is a GO:0044445 (cytosolic part)
2008-04-01 Updated RELATION part of GO:0000502 (proteasome complex)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2008-01-27 Updated DEFINITION A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex.
2008-01-21 Updated TERM proteasome core complex
2008-01-21 Added SYNONYM 26S proteasome
2008-01-21 Added SYNONYM proteasome core complex (sensu Bacteria)
2008-01-21 Added SYNONYM proteasome core complex (sensu Eukaryota)
2008-01-21 Added SECONDARY GO:0000503 (proteasome core complex (sensu Bacteria))
2007-08-09 Added SYNONYM 20S core complex
2007-08-09 Added SYNONYM macropain
2007-08-09 Deleted SYNONYM macropain
2007-08-09 Deleted SYNONYM 20S core complex
2007-01-18 Updated TERM proteasome core complex (sensu Eukaryota)
2007-01-15 Updated TERM proteasome core complex (sensu the Eukaryota research community)
2004-09-19 Updated TERM proteasome core complex (sensu Eukaryota)
2004-07-09 Updated DEFINITION A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex. This complex is involved in the proteolysis of substrates in an ATP dependent manner and consists of four ring-like structures, two outer and two inner, each containing seven subunits. As in, but not restricted to, the eukaryotes (Eukaryota, ncbi_taxonomy_id:2759).
2004-05-02 Updated DEFINITION A multisubunit barrel shaped endoprotease complex as seen in eukaryotes, which is the core of the proteasome complex. This complex is involved in the proteolysis of substrates in an ATP dependent manner and consists of four ring-like structures, two outer and two inner, each containing seven subunits.
2004-04-19 Added SYNONYM macropain
2004-04-16 Deleted SYNONYM macropain
2003-07-01 Updated DEFINITION A multisubunit barrel shaped endoprotease complex as seen in eukaryotes, which is the core of the proteasome complex. This complex is involved in the proteolysis of substrates in an ATP dependent manner and consists of four 'rings', two outer and two inner, each containing seven subunits.
2003-05-08 Updated TERM proteasome core complex (sensu Eukarya)
2003-05-08 Updated DEFINITION A multisubunit barrel shaped endoprotease complex as seen in eukaryotes, which is the core of the proteasome complex. This complex is involved in the proteolysis of substrates in an ATP dependent manner and consists of four "rings", two outer and two inner, each containing seven subunits.
2003-05-08 Added SYNONYM 20S core complex
2002-12-17 Updated TERM 20S core proteasome complex
2002-11-27 Added DEFINITION The 20S proteasome is an endoprotease complex that preferentially cleaves peptides C-terminal of hydrophobic, basic, and acidic residues. These activities can be classified as chymotrypsin-like, trypsin-like, and peptidyl-glutamyl peptide-hydrolyzing (PGPH) activity.
2002-02-06 Updated TERM 20S core proteasome
2001-11-13 Added SYNONYM macropain
2001-04-03 Updated TERM 20S core proteasome
2001-03-30 Added TERM 20S core proteasome

Term

Timestamp Action Category Detail
2008-01-21 Updated TERM proteasome core complex
2007-01-18 Updated TERM proteasome core complex (sensu Eukaryota)
2007-01-15 Updated TERM proteasome core complex (sensu the Eukaryota research community)
2004-09-19 Updated TERM proteasome core complex (sensu Eukaryota)
2003-05-08 Updated TERM proteasome core complex (sensu Eukarya)
2002-12-17 Updated TERM 20S core proteasome complex
2002-02-06 Updated TERM 20S core proteasome
2001-04-03 Updated TERM 20S core proteasome
2001-03-30 Added TERM 20S core proteasome

Definition/synonyms

Timestamp Action Category Detail
2009-12-06 Added SYNONYM 20S proteasome
2009-07-11 Deleted SYNONYM proteasome core complex (sensu Eukaryota)
2009-07-11 Deleted SYNONYM proteasome core complex (sensu Bacteria)
2009-02-25 Deleted SYNONYM 26S proteasome
2009-02-25 Added SYNONYM PA28gamma-20S proteasome
2008-05-13 Added DEFINITION A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex.
2008-05-12 Deleted DEFINITION A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex.
2008-01-27 Updated DEFINITION A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex.
2008-01-21 Added SYNONYM 26S proteasome
2008-01-21 Added SYNONYM proteasome core complex (sensu Bacteria)
2008-01-21 Added SYNONYM proteasome core complex (sensu Eukaryota)
2007-08-09 Added SYNONYM 20S core complex
2007-08-09 Added SYNONYM macropain
2007-08-09 Deleted SYNONYM macropain
2007-08-09 Deleted SYNONYM 20S core complex
2004-07-09 Updated DEFINITION A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex. This complex is involved in the proteolysis of substrates in an ATP dependent manner and consists of four ring-like structures, two outer and two inner, each containing seven subunits. As in, but not restricted to, the eukaryotes (Eukaryota, ncbi_taxonomy_id:2759).
2004-05-02 Updated DEFINITION A multisubunit barrel shaped endoprotease complex as seen in eukaryotes, which is the core of the proteasome complex. This complex is involved in the proteolysis of substrates in an ATP dependent manner and consists of four ring-like structures, two outer and two inner, each containing seven subunits.
2004-04-19 Added SYNONYM macropain
2004-04-16 Deleted SYNONYM macropain
2003-07-01 Updated DEFINITION A multisubunit barrel shaped endoprotease complex as seen in eukaryotes, which is the core of the proteasome complex. This complex is involved in the proteolysis of substrates in an ATP dependent manner and consists of four 'rings', two outer and two inner, each containing seven subunits.
2003-05-08 Updated DEFINITION A multisubunit barrel shaped endoprotease complex as seen in eukaryotes, which is the core of the proteasome complex. This complex is involved in the proteolysis of substrates in an ATP dependent manner and consists of four "rings", two outer and two inner, each containing seven subunits.
2003-05-08 Added SYNONYM 20S core complex
2002-11-27 Added DEFINITION The 20S proteasome is an endoprotease complex that preferentially cleaves peptides C-terminal of hydrophobic, basic, and acidic residues. These activities can be classified as chymotrypsin-like, trypsin-like, and peptidyl-glutamyl peptide-hydrolyzing (PGPH) activity.
2001-11-13 Added SYNONYM macropain

Relationships

Timestamp Action Category Detail
2008-07-28 Added RELATION is a GO:0044424 (intracellular part)
2008-07-28 Deleted RELATION is a GO:0044445 (cytosolic part)
2008-04-01 Updated RELATION is a GO:0044445 (cytosolic part)
2008-04-01 Updated RELATION part of GO:0000502 (proteasome complex)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)

Other

Timestamp Action Category Detail
2008-01-21 Added SECONDARY GO:0000503 (proteasome core complex (sensu Bacteria))
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