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GO:0005834 heterotrimeric G-protein complex

Term Information

ID GO:0005834
Name heterotrimeric G-protein complex
Ontology Cellular Component
Definition Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G-protein coupled receptors to an effector protein.
Comment See also the molecular function term 'G-protein coupled receptor activity ; GO:0004930'.
GONUTS GO:0005834 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related heterotrimeric G-protein GTPase activity
narrow heterotrimeric G-protein GTPase, gamma-subunit
narrow heterotrimeric G-protein GTPase, alpha-subunit
narrow heterotrimeric G-protein GTPase, beta-subunit

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

Protein complexes

Database ID Name
IntAct g-protein_yeast G protein heterotrimer

Cross-references

Database ID
InterPro IPR001770
InterPro IPR015898

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0000263 heterotrimeric G-protein GTPase, alpha-subunit CONSIDER GO:0005834
GO:0000264 heterotrimeric G-protein GTPase, beta-subunit CONSIDER GO:0005834
GO:0000265 heterotrimeric G-protein GTPase, gamma-subunit CONSIDER GO:0005834
GO:0003927 heterotrimeric G-protein GTPase activity REPLACEDBY GO:0005834
GO:0005065 heterotrimeric G-protein REPLACEDBY GO:0005834

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005834:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005834. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005834 based on the entire annotation set Co-occurrence statistics for GO:0005834 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-01-16 Added RELATION is a GO:0044459 (plasma membrane part)
2014-01-16 Added RELATION is a GO:0044424 (intracellular part)
2013-12-21 Added RELATION part of GO:0031234 (extrinsic component of cytoplasmic side of plasma membrane)
2013-12-21 Deleted RELATION is a GO:0031234 (extrinsic component of cytoplasmic side of plasma membrane)
2011-03-23 Added RELATION is a GO:0031234 (extrinsic component of cytoplasmic side of plasma membrane)
2011-03-23 Deleted RELATION is a GO:0019897 (extrinsic component of plasma membrane)
2008-05-13 Added DEFINITION Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G-protein coupled receptors to an effector protein.
2008-05-12 Deleted DEFINITION Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G-protein coupled receptors to an effector protein.
2008-04-01 Updated RELATION is a GO:0019897 (extrinsic component of plasma membrane)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2007-10-04 Deleted SYNONYM heterotrimeric G-protein
2007-08-09 Added SYNONYM heterotrimeric G-protein
2007-08-09 Added SYNONYM heterotrimeric G-protein GTPase activity
2007-08-09 Added SYNONYM heterotrimeric G-protein GTPase, alpha-subunit
2007-08-09 Added SYNONYM heterotrimeric G-protein GTPase, beta-subunit
2007-08-09 Added SYNONYM heterotrimeric G-protein GTPase, gamma-subunit
2007-08-09 Deleted SYNONYM heterotrimeric G-protein
2007-08-09 Deleted SYNONYM heterotrimeric G-protein GTPase activity
2007-08-09 Deleted SYNONYM heterotrimeric G-protein GTPase, alpha-subunit
2007-08-09 Deleted SYNONYM heterotrimeric G-protein GTPase, beta-subunit
2007-08-09 Deleted SYNONYM heterotrimeric G-protein GTPase, gamma-subunit
2005-08-10 Added SYNONYM heterotrimeric G-protein
2005-08-10 Added SYNONYM heterotrimeric G-protein GTPase activity
2005-08-10 Added SYNONYM heterotrimeric G-protein GTPase, alpha-subunit
2005-08-10 Added SYNONYM heterotrimeric G-protein GTPase, beta-subunit
2005-08-10 Added SYNONYM heterotrimeric G-protein GTPase, gamma-subunit
2004-07-22 Updated DEFINITION Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G-protein coupled receptors to an effector protein.
2002-11-27 Updated DEFINITION Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G-protein coupled receptors (GO:0004930) to an effector protein.
2002-02-06 Updated TERM heterotrimeric G-protein complex
2001-08-06 Added DEFINITION Any of a family of heterotrimeric GTP-binding and hydrolising proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and Ras. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer.
2001-04-03 Updated TERM heterotrimeric G-protein complex
2001-03-30 Added TERM heterotrimeric G-protein complex

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM heterotrimeric G-protein complex
2001-04-03 Updated TERM heterotrimeric G-protein complex
2001-03-30 Added TERM heterotrimeric G-protein complex

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G-protein coupled receptors to an effector protein.
2008-05-12 Deleted DEFINITION Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G-protein coupled receptors to an effector protein.
2007-10-04 Deleted SYNONYM heterotrimeric G-protein
2007-08-09 Added SYNONYM heterotrimeric G-protein
2007-08-09 Added SYNONYM heterotrimeric G-protein GTPase activity
2007-08-09 Added SYNONYM heterotrimeric G-protein GTPase, alpha-subunit
2007-08-09 Added SYNONYM heterotrimeric G-protein GTPase, beta-subunit
2007-08-09 Added SYNONYM heterotrimeric G-protein GTPase, gamma-subunit
2007-08-09 Deleted SYNONYM heterotrimeric G-protein
2007-08-09 Deleted SYNONYM heterotrimeric G-protein GTPase activity
2007-08-09 Deleted SYNONYM heterotrimeric G-protein GTPase, alpha-subunit
2007-08-09 Deleted SYNONYM heterotrimeric G-protein GTPase, beta-subunit
2007-08-09 Deleted SYNONYM heterotrimeric G-protein GTPase, gamma-subunit
2005-08-10 Added SYNONYM heterotrimeric G-protein
2005-08-10 Added SYNONYM heterotrimeric G-protein GTPase activity
2005-08-10 Added SYNONYM heterotrimeric G-protein GTPase, alpha-subunit
2005-08-10 Added SYNONYM heterotrimeric G-protein GTPase, beta-subunit
2005-08-10 Added SYNONYM heterotrimeric G-protein GTPase, gamma-subunit
2004-07-22 Updated DEFINITION Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G-protein coupled receptors to an effector protein.
2002-11-27 Updated DEFINITION Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G-protein coupled receptors (GO:0004930) to an effector protein.
2001-08-06 Added DEFINITION Any of a family of heterotrimeric GTP-binding and hydrolising proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and Ras. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer.

Relationships

Timestamp Action Category Detail
2014-01-16 Added RELATION is a GO:0044459 (plasma membrane part)
2014-01-16 Added RELATION is a GO:0044424 (intracellular part)
2013-12-21 Added RELATION part of GO:0031234 (extrinsic component of cytoplasmic side of plasma membrane)
2013-12-21 Deleted RELATION is a GO:0031234 (extrinsic component of cytoplasmic side of plasma membrane)
2011-03-23 Added RELATION is a GO:0031234 (extrinsic component of cytoplasmic side of plasma membrane)
2011-03-23 Deleted RELATION is a GO:0019897 (extrinsic component of plasma membrane)
2008-04-01 Updated RELATION is a GO:0019897 (extrinsic component of plasma membrane)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
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