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GO:0005834 heterotrimeric G-protein complexAny of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G-protein coupled receptors to an effector protein.
Term Information
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| Type | Synonym |
| narrow | heterotrimeric G-protein GTPase, alpha-subunit |
| narrow | heterotrimeric G-protein GTPase, gamma-subunit |
| narrow | heterotrimeric G-protein GTPase, beta-subunit |
| related | heterotrimeric G-protein GTPase activity |
| Database | ID |
| INTERPRO | IPR001770 |
| INTERPRO | IPR015898 |
GO:0003927 heterotrimeric G-protein GTPase activity |
(replaced_by GO:0005834) |
GO:0005065 heterotrimeric G-protein |
(replaced_by GO:0005834) |
GO:0000263 heterotrimeric G-protein GTPase, alpha-subunit |
(consider GO:0005834) |
GO:0000265 heterotrimeric G-protein GTPase, gamma-subunit |
(consider GO:0005834) |
GO:0000264 heterotrimeric G-protein GTPase, beta-subunit |
(consider GO:0005834) |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0005575 cellular_component | |||||||||||
![]() | GO:0032991 macromolecular complex | ||||||||||
![]() | ![]() | GO:0005623 cell | |||||||||
![]() | ![]() | ![]() | GO:0043234 protein complex | ||||||||
![]() | ![]() | ![]() | ![]() | GO:0044464 cell part | |||||||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0016020 membrane | ||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0005886 plasma membrane | |||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0044425 membrane part | ||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0019898 extrinsic to membrane | |||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0044459 plasma membrane part | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0019897 extrinsic to plasma membrane | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0005834 heterotrimeric G-protein complex |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-8.ebi.ac.uk |
| Uptime | 17:46 13/10/2009 |
| Data version | 2009-11-29-04-02-58 |