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GO:0005794 Golgi apparatus

A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.

Term Information

ID	GO:0005794
Name	Golgi apparatus
Ontology	Cellular Component
Definition	A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
Comment	Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon.

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

	GO slim name	Count of all terms
	goslim_candida	91
	goslim_generic	127
	goslim_pir	470
	goslim_plant	102
	goslim_yeast	93

Synonyms

Type	Synonym
broad	Golgi
narrow	Golgi ribbon
exact	Golgi complex

Cross-references associated with this term:

Database	ID
INTERPRO	IPR000744
INTERPRO	IPR014615
INTERPRO	IPR017105
INTERPRO	IPR017108
INTERPRO	IPR017107
INTERPRO	IPR002516
INTERPRO	IPR018477
INTERPRO	IPR005331
INTERPRO	IPR004901
Wikipedia	Golgi_apparatus
INTERPRO	IPR009729

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GO:0005575 cellular_component

GO:0043226 organelle

GO:0005623 cell

GO:0043227 membrane-bounded organelle

GO:0044464 cell part

GO:0005622 intracellular

GO:0044424 intracellular part

GO:0005737 cytoplasm

GO:0043229 intracellular organelle

GO:0044444 cytoplasmic part

GO:0043231 intracellular membrane-bounded organelle

GO:0005794 Golgi apparatus

Relationship key

Code	Relationship
	part of
	is a
	regulates
	+ve regulates
	-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:

P	GO:0044431 Golgi apparatus part

Relationship key

Code	Relationship
P	part of
I	is a

Protein Annotation

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Co-occurring Terms

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