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GO:0005790 smooth endoplasmic reticulum

The smooth endoplasmic reticulum (ER) has with no ribosomes attached to it. The smooth is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER.

Term Information

ID GO:0005790
Name smooth endoplasmic reticulum
Ontology Cellular Component
Definition The smooth endoplasmic reticulum (ER) has with no ribosomes attached to it. The smooth is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER.
Comment

Synonyms

Type Synonym
exact smooth ER
exact SER

Cross-references associated with this term:

Database ID
Wikipedia Endoplasmic_reticulum#Smooth_endoplasmic_reticulum

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Ancestor Chart

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Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0005575 cellular_component
GO:0043226 organelle
GO:0005623 cell
GO:0043227 membrane-bounded organelle
GO:0044464 cell part
GO:0005622 intracellular
GO:0044424 intracellular part
GO:0005737 cytoplasm
GO:0043229 intracellular organelle
GO:0044444 cytoplasmic part
GO:0043231 intracellular membrane-bounded organelle
GO:0005783 endoplasmic reticulum
GO:0005790 smooth endoplasmic reticulum

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
P GO:0048238 smooth endoplasmic reticulum lumen
P GO:0030868 smooth endoplasmic reticulum membrane
P GO:0016029 subrhabdomeral cisterna

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Co-occurring Terms

Co-occurrence statistics

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