spacer

GO:0005783 endoplasmic reticulum

Term Information

ID GO:0005783
Name endoplasmic reticulum
Ontology Cellular Component
Definition The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
GONUTS GO:0005783 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact ER

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0005623 cell only_in_taxon 131567 cellular organisms
GO:0005783 endoplasmic reticulum only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_metagenomics119
goslim_candida89
goslim_generic149
goslim_pir462
goslim_plant99
goslim_yeast169
goslim_aspergillus85
goslim_chembl309

Cross-references

Database ID
InterPro IPR000493
InterPro IPR001006
InterPro IPR001580
InterPro IPR005792
InterPro IPR007266
InterPro IPR007528
InterPro IPR007676
InterPro IPR007873
InterPro IPR008417
InterPro IPR008504
InterPro IPR008855
InterPro IPR008856
InterPro IPR009169
InterPro IPR010483
InterPro IPR010580
InterPro IPR011679
InterPro IPR013547
InterPro IPR014615
InterPro IPR016439
InterPro IPR016565
InterPro IPR017378
InterPro IPR019623
InterPro IPR021170
InterPro IPR025752
InterPro IPR025770
InterPro IPR026208
InterPro IPR027533
InterPro IPR027670
InterPro IPR029669
InterPro IPR030327
InterPro IPR030330
InterPro IPR030332
InterPro IPR030553
InterPro IPR031884
InterPro IPR033212
InterPro IPR033294
InterPro IPR033528
InterPro IPR033670
InterPro IPR033675
InterPro IPR033677
InterPro IPR033678
InterPro IPR033679
InterPro IPR033680
InterPro IPR033681
NIF_Subcellular sao1036339110
UniProtKB-KW Endoplasmic reticulum
UniProtKB-SubCell Endoplasmic reticulum
Wikipedia Endoplasmic_reticulum

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0005045 obsolete endoplasmic reticulum receptor activity CONSIDER GO:0005783
GO:0006459 obsolete binding unfolded ER proteins CONSIDER GO:0005783
GO:0006889 obsolete regulation of calcium in ER CONSIDER GO:0005783
GO:0045783 obsolete negative regulation of calcium in ER CONSIDER GO:0005783
GO:0045784 obsolete positive regulation of calcium in ER CONSIDER GO:0005783

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005783:
Relationship To GO:0005783 Child Term Child Term Name
Part of GO:0000835 ER ubiquitin ligase complex
Is a GO:0005790 smooth endoplasmic reticulum
Is a GO:0005791 rough endoplasmic reticulum
Is a GO:0016529 sarcoplasmic reticulum
Occurs in GO:0032469 endoplasmic reticulum calcium ion homeostasis
Occurs in GO:0033577 protein glycosylation in endoplasmic reticulum
Occurs in GO:0033579 protein galactosylation in endoplasmic reticulum
Occurs in GO:0035437 maintenance of protein localization in endoplasmic reticulum
Part of GO:0044432 endoplasmic reticulum part
Part of GO:0071781 endoplasmic reticulum cisternal network
Part of GO:0071782 endoplasmic reticulum tubular network
Is a GO:0009511 plasmodesmatal endoplasmic reticulum
Part of GO:1990529 glycosylphosphatidylinositol-mannosyltransferase I complex
Part of GO:0098827 endoplasmic reticulum subcompartment
Is a GO:1990007 membrane stack

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005783. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005783 based on the entire annotation set Co-occurrence statistics for GO:0005783 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2015-05-19 Added SLIM goslim_chembl
2015-05-19 Deleted SLIM goslim_ChEMBL
2015-05-11 Added SLIM goslim_ChEMBL
2014-01-24 Added RELATION part of GO:0012505 (endomembrane system)
2013-04-18 Updated SLIM goslim_aspergillus
2013-04-18 Updated SLIM goslim_yeast
2013-04-18 Updated SLIM goslim_plant
2013-04-18 Updated SLIM goslim_pir
2013-04-18 Updated SLIM goslim_generic
2013-04-18 Updated SLIM goslim_candida
2013-04-18 Updated SLIM goslim_metagenomics
2012-02-17 Added SLIM goslim_metagenomics
2011-11-05 Added SLIM goslim_aspergillus
2010-02-04 Added XREF NIF_Subcellular:sao1036339110
2009-02-08 Added XREF Wikipedia:Endoplasmic_reticulum
2008-06-09 Added SLIM goslim_yeast
2008-06-09 Added SLIM goslim_plant
2008-06-09 Added SLIM goslim_pir
2008-06-09 Added SLIM goslim_generic
2008-06-09 Added SLIM goslim_candida
2008-05-13 Added DEFINITION The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
2008-05-12 Deleted DEFINITION The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
2008-04-01 Updated RELATION is a GO:0044444 (cytoplasmic part)
2008-04-01 Updated RELATION is a GO:0043231 (intracellular membrane-bounded organelle)
2007-08-09 Added SYNONYM ER
2007-08-09 Deleted SYNONYM ER
2005-08-20 Deleted SYNONYM regulation of calcium in ER
2005-08-20 Deleted SYNONYM binding unfolded ER proteins
2005-08-20 Deleted SYNONYM endoplasmic reticulum receptor activity
2005-08-20 Deleted SYNONYM negative regulation of calcium in ER
2005-08-20 Deleted SYNONYM positive regulation of calcium in ER
2005-08-10 Added SYNONYM binding unfolded ER proteins
2005-08-10 Added SYNONYM endoplasmic reticulum receptor activity
2005-08-10 Added SYNONYM negative regulation of calcium in ER
2005-08-10 Added SYNONYM positive regulation of calcium in ER
2005-08-10 Added SYNONYM regulation of calcium in ER
2004-04-19 Added SYNONYM ER
2004-04-16 Deleted SYNONYM ER
2002-11-27 Added DEFINITION The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
2002-02-06 Updated TERM endoplasmic reticulum
2001-04-03 Updated TERM endoplasmic reticulum
2001-03-30 Added SYNONYM ER
2001-03-30 Added TERM endoplasmic reticulum

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM endoplasmic reticulum
2001-04-03 Updated TERM endoplasmic reticulum
2001-03-30 Added TERM endoplasmic reticulum

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
2008-05-12 Deleted DEFINITION The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
2007-08-09 Added SYNONYM ER
2007-08-09 Deleted SYNONYM ER
2005-08-20 Deleted SYNONYM regulation of calcium in ER
2005-08-20 Deleted SYNONYM binding unfolded ER proteins
2005-08-20 Deleted SYNONYM endoplasmic reticulum receptor activity
2005-08-20 Deleted SYNONYM negative regulation of calcium in ER
2005-08-20 Deleted SYNONYM positive regulation of calcium in ER
2005-08-10 Added SYNONYM binding unfolded ER proteins
2005-08-10 Added SYNONYM endoplasmic reticulum receptor activity
2005-08-10 Added SYNONYM negative regulation of calcium in ER
2005-08-10 Added SYNONYM positive regulation of calcium in ER
2005-08-10 Added SYNONYM regulation of calcium in ER
2004-04-19 Added SYNONYM ER
2004-04-16 Deleted SYNONYM ER
2002-11-27 Added DEFINITION The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
2001-03-30 Added SYNONYM ER

Relationships

Timestamp Action Category Detail
2014-01-24 Added RELATION part of GO:0012505 (endomembrane system)
2008-04-01 Updated RELATION is a GO:0044444 (cytoplasmic part)
2008-04-01 Updated RELATION is a GO:0043231 (intracellular membrane-bounded organelle)

Cross-references

Timestamp Action Category Detail
2010-02-04 Added XREF NIF_Subcellular:sao1036339110
2009-02-08 Added XREF Wikipedia:Endoplasmic_reticulum

Other

Timestamp Action Category Detail
2015-05-19 Added SLIM goslim_chembl
2015-05-19 Deleted SLIM goslim_ChEMBL
2015-05-11 Added SLIM goslim_ChEMBL
2013-04-18 Updated SLIM goslim_aspergillus
2013-04-18 Updated SLIM goslim_yeast
2013-04-18 Updated SLIM goslim_plant
2013-04-18 Updated SLIM goslim_pir
2013-04-18 Updated SLIM goslim_generic
2013-04-18 Updated SLIM goslim_candida
2013-04-18 Updated SLIM goslim_metagenomics
2012-02-17 Added SLIM goslim_metagenomics
2011-11-05 Added SLIM goslim_aspergillus
2008-06-09 Added SLIM goslim_yeast
2008-06-09 Added SLIM goslim_plant
2008-06-09 Added SLIM goslim_pir
2008-06-09 Added SLIM goslim_generic
2008-06-09 Added SLIM goslim_candida
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
13ms