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GO:0005770 late endosome

Term Information

ID GO:0005770
Name late endosome
Ontology Cellular Component
Definition A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
PMID:11964142 PMID:2557062
GONUTS GO:0005770 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad PVC
exact prevacuolar compartment

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000061 GO:0005768 endosome only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

Cross-references

Database ID
UniProtKB-SubCell Late endosome
UniProtKB-SubCell Prevacuolar compartment

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005770:
Relationship To GO:0005770 Child Term Child Term Name
Part of GO:0031902 late endosome membrane
Part of GO:0031906 late endosome lumen
Is a GO:0005771 multivesicular body
Part of GO:0035658 Mon1-Ccz1 complex

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005770. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005770 based on the entire annotation set Co-occurrence statistics for GO:0005770 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-05-13 Added DEFINITION A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
2008-05-12 Deleted DEFINITION A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
2008-04-01 Updated RELATION is a GO:0005768 (endosome)
2007-08-09 Added SYNONYM PVC
2007-08-09 Added SYNONYM prevacuolar compartment
2007-08-09 Deleted SYNONYM PVC
2007-08-09 Deleted SYNONYM prevacuolar compartment
2006-08-15 Updated DEFINITION A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
2004-04-26 Added SYNONYM PVC
2004-04-19 Added SYNONYM prevacuolar compartment
2004-04-16 Deleted SYNONYM prevacuolar compartment
2004-03-19 Updated DEFINITION A prelysosomal endocytic organelle defined by the time it takes for endocytosed macromolecules to be delivered. The time of delivery may vary ; for example, late endosomes are usually loaded 4-30 min after endocytic uptake in mammalian cells. late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. They are differentiated from early endosomes by their lower lumenal pH and different protein composition.
2004-03-12 Updated DEFINITION A prelysosomal endocytic organelle defined by the time it takes for endocytosed macromolecules to be delivered. The time of delivery may vary ; for example, late endosomes are usually loaded 4-30?min after endocytic uptake in mammalian cells. late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. They are differentiated from early endosomes by their lower lumenal pH and different protein composition.
2004-03-11 Added DEFINITION A prelysosomal endocytic organelle defined by the time it takes for endocytosed macromolecules to be delivered. The time of delivery may vary ; for example, late endosomes are usually loaded 4-30�min after endocytic uptake in mammalian cells. late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. They are differentiated from early endosomes by their lower lumenal pH and different protein composition.
2002-08-20 Added SYNONYM prevacuolar compartment
2002-02-06 Updated TERM late endosome
2001-04-03 Updated TERM late endosome
2001-03-30 Added TERM late endosome

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM late endosome
2001-04-03 Updated TERM late endosome
2001-03-30 Added TERM late endosome

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
2008-05-12 Deleted DEFINITION A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
2007-08-09 Added SYNONYM PVC
2007-08-09 Added SYNONYM prevacuolar compartment
2007-08-09 Deleted SYNONYM PVC
2007-08-09 Deleted SYNONYM prevacuolar compartment
2006-08-15 Updated DEFINITION A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
2004-04-26 Added SYNONYM PVC
2004-04-19 Added SYNONYM prevacuolar compartment
2004-04-16 Deleted SYNONYM prevacuolar compartment
2004-03-19 Updated DEFINITION A prelysosomal endocytic organelle defined by the time it takes for endocytosed macromolecules to be delivered. The time of delivery may vary ; for example, late endosomes are usually loaded 4-30 min after endocytic uptake in mammalian cells. late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. They are differentiated from early endosomes by their lower lumenal pH and different protein composition.
2004-03-12 Updated DEFINITION A prelysosomal endocytic organelle defined by the time it takes for endocytosed macromolecules to be delivered. The time of delivery may vary ; for example, late endosomes are usually loaded 4-30?min after endocytic uptake in mammalian cells. late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. They are differentiated from early endosomes by their lower lumenal pH and different protein composition.
2004-03-11 Added DEFINITION A prelysosomal endocytic organelle defined by the time it takes for endocytosed macromolecules to be delivered. The time of delivery may vary ; for example, late endosomes are usually loaded 4-30�min after endocytic uptake in mammalian cells. late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. They are differentiated from early endosomes by their lower lumenal pH and different protein composition.
2002-08-20 Added SYNONYM prevacuolar compartment

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0005768 (endosome)
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