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GO:0005764 lysosome

A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.

Term Information

ID GO:0005764
Name lysosome
Ontology Cellular Component
Definition A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
Comment

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_generic127
goslim_plant102

Cross-references associated with this term:

Database ID
INTERPRO IPR001139
INTERPRO IPR005429
Wikipedia Lysosome
INTERPRO IPR015981
INTERPRO IPR016699
INTERPRO IPR008373

This term can be used instead of these obsolete terms:

GO:0004212 lysosomal cysteine-type endopeptidase (consider GO:0005764)
GO:0017029 lysosomal protein stabilization (consider GO:0005764)

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Ancestor Chart

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0005575 cellular_component
GO:0043226 organelle
GO:0005623 cell
GO:0043227 membrane-bounded organelle
GO:0044464 cell part
GO:0005622 intracellular
GO:0044424 intracellular part
GO:0005737 cytoplasm
GO:0044444 cytoplasmic part
GO:0043229 intracellular organelle
GO:0043231 intracellular membrane-bounded organelle
GO:0005773 vacuole
GO:0000323 lytic vacuole
GO:0005764 lysosome

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0042629 mast cell granule
I GO:0043246 megasome
P GO:0005765 lysosomal membrane
I GO:0005766 primary lysosome
I GO:0005767 secondary lysosome
P GO:0043202 lysosomal lumen
P GO:0070622 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex
I GO:0044194 cytolytic granule
P GO:0070559 lysosomal multienzyme complex

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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