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GO:0005764 lysosome

Term Information

ID GO:0005764
Name lysosome
Ontology Cellular Component
Definition A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
GONUTS GO:0005764 Wiki Page

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000062 GO:0005773 vacuole only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_generic148
goslim_plant100

Cross-references

Database ID
InterPro IPR005429
InterPro IPR008373
InterPro IPR015981
InterPro IPR016699
InterPro IPR021165
InterPro IPR026138
NIF_Subcellular sao585356902
UniProtKB-KW Lysosome
UniProtKB-SubCell Lysosome
Wikipedia Lysosome

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0004212 lysosomal cysteine-type endopeptidase CONSIDER GO:0005764
GO:0017029 lysosomal protein stabilization CONSIDER GO:0005764

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005764:
Relationship To GO:0005764 Child Term Child Term Name
Is a GO:0042629 mast cell granule
Is a GO:0043246 megasome
Part of GO:0005765 lysosomal membrane
Is a GO:0005766 primary lysosome
Is a GO:0005767 secondary lysosome
Part of GO:0043202 lysosomal lumen
Part of GO:0070622 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex
Is a GO:0044194 cytolytic granule
Part of GO:0090123 lysosomal glycocalyx
Part of GO:0070559 lysosomal multienzyme complex
Is a GO:0036019 endolysosome

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005764. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005764 based on the entire annotation set Co-occurrence statistics for GO:0005764 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_plant
2013-04-18 Updated SLIM goslim_generic
2010-02-04 Added XREF NIF_Subcellular:sao585356902
2009-03-03 Deleted DEFINITION A cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2009-03-03 Added DEFINITION A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2009-02-08 Added XREF Wikipedia:Lysosome
2008-10-21 Deleted DEFINITION Any of a group of related cytoplasmic, membrane-bounded organelles that are found in most animal cells and that contain a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2008-10-21 Added DEFINITION A cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2008-10-02 Added DEFINITION Any of a group of related cytoplasmic, membrane-bounded organelles that are found in most animal cells and that contain a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2008-10-02 Deleted DEFINITION Any of a group of related cytoplasmic, membrane bound organelles that are found in most animal cells and that contain a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2008-06-09 Added SLIM goslim_plant
2008-06-09 Added SLIM goslim_generic
2008-05-13 Added DEFINITION Any of a group of related cytoplasmic, membrane bound organelles that are found in most animal cells and that contain a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2008-05-12 Deleted DEFINITION Any of a group of related cytoplasmic, membrane bound organelles that are found in most animal cells and that contain a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2008-04-01 Updated RELATION is a GO:0000323 (lytic vacuole)
2007-10-16 Deleted SYNONYM lysosomal cysteine-type endopeptidase
2007-10-16 Deleted SYNONYM lysosomal protein stabilization
2007-08-09 Added SYNONYM lysosomal cysteine-type endopeptidase
2007-08-09 Added SYNONYM lysosomal protein stabilization
2007-08-09 Deleted SYNONYM lysosomal cysteine-type endopeptidase
2007-08-09 Deleted SYNONYM lysosomal protein stabilization
2005-08-10 Added SYNONYM lysosomal cysteine-type endopeptidase
2005-08-10 Added SYNONYM lysosomal protein stabilization
2002-11-27 Added DEFINITION Any of a group of related cytoplasmic, membrane bound organelles that are found in most animal cells and that contain a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2002-02-06 Updated TERM lysosome
2001-04-03 Updated TERM lysosome
2001-03-30 Added TERM lysosome

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM lysosome
2001-04-03 Updated TERM lysosome
2001-03-30 Added TERM lysosome

Definition/synonyms

Timestamp Action Category Detail
2009-03-03 Deleted DEFINITION A cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2009-03-03 Added DEFINITION A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2008-10-21 Deleted DEFINITION Any of a group of related cytoplasmic, membrane-bounded organelles that are found in most animal cells and that contain a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2008-10-21 Added DEFINITION A cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2008-10-02 Added DEFINITION Any of a group of related cytoplasmic, membrane-bounded organelles that are found in most animal cells and that contain a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2008-10-02 Deleted DEFINITION Any of a group of related cytoplasmic, membrane bound organelles that are found in most animal cells and that contain a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2008-05-13 Added DEFINITION Any of a group of related cytoplasmic, membrane bound organelles that are found in most animal cells and that contain a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2008-05-12 Deleted DEFINITION Any of a group of related cytoplasmic, membrane bound organelles that are found in most animal cells and that contain a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2007-10-16 Deleted SYNONYM lysosomal cysteine-type endopeptidase
2007-10-16 Deleted SYNONYM lysosomal protein stabilization
2007-08-09 Added SYNONYM lysosomal cysteine-type endopeptidase
2007-08-09 Added SYNONYM lysosomal protein stabilization
2007-08-09 Deleted SYNONYM lysosomal cysteine-type endopeptidase
2007-08-09 Deleted SYNONYM lysosomal protein stabilization
2005-08-10 Added SYNONYM lysosomal cysteine-type endopeptidase
2005-08-10 Added SYNONYM lysosomal protein stabilization
2002-11-27 Added DEFINITION Any of a group of related cytoplasmic, membrane bound organelles that are found in most animal cells and that contain a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0000323 (lytic vacuole)

Cross-references

Timestamp Action Category Detail
2010-02-04 Added XREF NIF_Subcellular:sao585356902
2009-02-08 Added XREF Wikipedia:Lysosome

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_plant
2013-04-18 Updated SLIM goslim_generic
2008-06-09 Added SLIM goslim_plant
2008-06-09 Added SLIM goslim_generic
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