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GO:0005747 mitochondrial respiratory chain complex I

Term Information

ID GO:0005747
Name mitochondrial respiratory chain complex I
Ontology Cellular Component
Definition A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
Secondary IDs GO:0005748
GONUTS GO:0005747 Wiki Page

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0005623 cell only_in_taxon 131567 cellular organisms
GO:0005739 mitochondrion only_in_taxon 2759 Eukaryota
GO:0045271 respiratory chain complex I never_in_taxon 4896 Schizosaccharomyces pombe PMID:21597881
GO:0045271 respiratory chain complex I never_in_taxon 4932 Saccharomyces cerevisiae PMID:21597881
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR012576
InterPro IPR015828
InterPro IPR016551
InterPro IPR016668
InterPro IPR016680
InterPro IPR026192
InterPro IPR026193
InterPro IPR026626
InterPro IPR026627
InterPro IPR033034

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005747:
Relationship To GO:0005747 Child Term Child Term Name
Part of GO:0042652 mitochondrial respiratory chain complex I, peripheral segment
Part of GO:0042653 mitochondrial respiratory chain complex I, membrane segment

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005747. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005747 based on the entire annotation set Co-occurrence statistics for GO:0005747 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2015-06-25 Deleted RELATION is a GO:0044455 (mitochondrial membrane part)
2015-05-11 Added RELATION is a GO:0098800 (inner mitochondrial membrane protein complex)
2015-04-24 Added RELATION part of GO:0005739 (mitochondrion)
2013-02-02 Deleted RELATION part of GO:0005739 (mitochondrion)
2012-10-29 Added RELATION part of GO:0005739 (mitochondrion)
2009-07-11 Deleted SYNONYM respiratory chain complex I (sensu Eukaryota)
2009-07-11 Deleted SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukaryota)
2008-06-30 Added DEFINITION A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
2008-06-30 Deleted DEFINITION A part of the respiratory chain located in the mitochondrion. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
2008-05-13 Added DEFINITION A part of the respiratory chain located in the mitochondrion. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
2008-05-12 Deleted DEFINITION A part of the respiratory chain located in the mitochondrion. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
2008-04-01 Updated RELATION is a GO:0044455 (mitochondrial membrane part)
2008-04-01 Updated RELATION is a GO:0045271 (respiratory chain complex I)
2008-04-01 Updated RELATION part of GO:0005746 (mitochondrial respiratory chain)
2007-08-09 Added SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukaryota)
2007-08-09 Added SYNONYM respiratory chain complex I (sensu Eukaryota)
2007-08-09 Deleted SYNONYM respiratory chain complex I (sensu Eukaryota)
2007-08-09 Deleted SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukaryota)
2007-02-16 Updated DEFINITION A part of the respiratory chain located in the mitochondrion. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
2007-02-12 Added SYNONYM respiratory chain complex I (sensu Eukaryota)
2007-02-12 Updated TERM mitochondrial respiratory chain complex I
2007-01-18 Deleted SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu the Eukaryota research community)
2007-01-18 Added SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukaryota)
2007-01-18 Updated TERM respiratory chain complex I (sensu Eukaryota)
2007-01-15 Updated TERM respiratory chain complex I (sensu the Eukaryota research community)
2007-01-15 Deleted SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukaryota)
2007-01-15 Added SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu the Eukaryota research community)
2005-07-09 Deleted SYNONYM NADH dehydrogenase (ubiquinone)
2004-09-19 Deleted SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukarya)
2004-09-19 Added SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukaryota)
2004-09-19 Updated TERM respiratory chain complex I (sensu Eukaryota)
2004-07-09 Updated DEFINITION A part of the respiratory chain, containing about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron; the iron undergoes oxidation-reduction between Fe(II) and Fe(III). Catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. As in, but not restricted to, the eukaryotes (Eukaryota, ncbi_taxonomy_id:2759).
2004-04-19 Added SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukarya)
2004-04-16 Deleted SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukarya)
2003-04-12 Added SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukarya)
2003-04-12 Added SECONDARY GO:0005748 (NADH dehydrogenase complex (ubiquinone) (sensu Eukarya))
2002-11-27 Updated DEFINITION A part of the respiratory chain, containing about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron; the iron undergoes oxidation-reduction between Fe(II) and Fe(III). Catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. Found in eukaryotes.
2002-05-10 Updated TERM respiratory chain complex I (sensu Eukarya)
2002-02-06 Updated TERM respiratory chain complex I
2001-08-06 Added DEFINITION A part of the respiratory chain, containing about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron; the iron undergoes oxidation-reduction between Fe(II) and Fe(III). Catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
2001-06-29 Added SYNONYM NADH dehydrogenase (ubiquinone)
2001-04-03 Updated TERM respiratory chain complex I
2001-03-30 Added TERM respiratory chain complex I

Term

Timestamp Action Category Detail
2007-02-12 Updated TERM mitochondrial respiratory chain complex I
2007-01-18 Updated TERM respiratory chain complex I (sensu Eukaryota)
2007-01-15 Updated TERM respiratory chain complex I (sensu the Eukaryota research community)
2004-09-19 Updated TERM respiratory chain complex I (sensu Eukaryota)
2002-05-10 Updated TERM respiratory chain complex I (sensu Eukarya)
2002-02-06 Updated TERM respiratory chain complex I
2001-04-03 Updated TERM respiratory chain complex I
2001-03-30 Added TERM respiratory chain complex I

Definition/synonyms

Timestamp Action Category Detail
2009-07-11 Deleted SYNONYM respiratory chain complex I (sensu Eukaryota)
2009-07-11 Deleted SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukaryota)
2008-06-30 Added DEFINITION A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
2008-06-30 Deleted DEFINITION A part of the respiratory chain located in the mitochondrion. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
2008-05-13 Added DEFINITION A part of the respiratory chain located in the mitochondrion. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
2008-05-12 Deleted DEFINITION A part of the respiratory chain located in the mitochondrion. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
2007-08-09 Added SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukaryota)
2007-08-09 Added SYNONYM respiratory chain complex I (sensu Eukaryota)
2007-08-09 Deleted SYNONYM respiratory chain complex I (sensu Eukaryota)
2007-08-09 Deleted SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukaryota)
2007-02-16 Updated DEFINITION A part of the respiratory chain located in the mitochondrion. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
2007-02-12 Added SYNONYM respiratory chain complex I (sensu Eukaryota)
2007-01-18 Deleted SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu the Eukaryota research community)
2007-01-18 Added SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukaryota)
2007-01-15 Deleted SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukaryota)
2007-01-15 Added SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu the Eukaryota research community)
2005-07-09 Deleted SYNONYM NADH dehydrogenase (ubiquinone)
2004-09-19 Deleted SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukarya)
2004-09-19 Added SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukaryota)
2004-07-09 Updated DEFINITION A part of the respiratory chain, containing about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron; the iron undergoes oxidation-reduction between Fe(II) and Fe(III). Catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. As in, but not restricted to, the eukaryotes (Eukaryota, ncbi_taxonomy_id:2759).
2004-04-19 Added SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukarya)
2004-04-16 Deleted SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukarya)
2003-04-12 Added SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukarya)
2002-11-27 Updated DEFINITION A part of the respiratory chain, containing about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron; the iron undergoes oxidation-reduction between Fe(II) and Fe(III). Catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. Found in eukaryotes.
2001-08-06 Added DEFINITION A part of the respiratory chain, containing about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron; the iron undergoes oxidation-reduction between Fe(II) and Fe(III). Catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
2001-06-29 Added SYNONYM NADH dehydrogenase (ubiquinone)

Relationships

Timestamp Action Category Detail
2015-06-25 Deleted RELATION is a GO:0044455 (mitochondrial membrane part)
2015-05-11 Added RELATION is a GO:0098800 (inner mitochondrial membrane protein complex)
2015-04-24 Added RELATION part of GO:0005739 (mitochondrion)
2013-02-02 Deleted RELATION part of GO:0005739 (mitochondrion)
2012-10-29 Added RELATION part of GO:0005739 (mitochondrion)
2008-04-01 Updated RELATION is a GO:0044455 (mitochondrial membrane part)
2008-04-01 Updated RELATION is a GO:0045271 (respiratory chain complex I)
2008-04-01 Updated RELATION part of GO:0005746 (mitochondrial respiratory chain)

Other

Timestamp Action Category Detail
2003-04-12 Added SECONDARY GO:0005748 (NADH dehydrogenase complex (ubiquinone) (sensu Eukarya))
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