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GO:0005730 nucleolus

Term Information

ID GO:0005730
Name nucleolus
Ontology Cellular Component
Definition A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
GONUTS GO:0005730 Wiki Page

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000059 GO:0005634 nucleus only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_candida89
goslim_generic149
goslim_pir462
goslim_plant100
goslim_yeast169
goslim_aspergillus85

Cross-references

Database ID
InterPro IPR002415
InterPro IPR010613
InterPro IPR016443
InterPro IPR016580
InterPro IPR017265
InterPro IPR018983
InterPro IPR024926
InterPro IPR024929
InterPro IPR026257
InterPro IPR026747
InterPro IPR028160
InterPro IPR029565
NIF_Subcellular sao1820400233
UniProtKB-SubCell Nucleolus
Wikipedia Nucleolus

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005730:
Relationship To GO:0005730 Child Term Child Term Name
Part of GO:0044452 nucleolar part

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005730. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005730 based on the entire annotation set Co-occurrence statistics for GO:0005730 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_aspergillus
2013-04-18 Updated SLIM goslim_yeast
2013-04-18 Updated SLIM goslim_plant
2013-04-18 Updated SLIM goslim_pir
2013-04-18 Updated SLIM goslim_generic
2013-04-18 Updated SLIM goslim_candida
2011-11-05 Added SLIM goslim_aspergillus
2010-02-04 Added XREF NIF_Subcellular:sao1820400233
2009-02-05 Added XREF Wikipedia:Nucleolus
2008-06-09 Added SLIM goslim_yeast
2008-06-09 Added SLIM goslim_plant
2008-06-09 Added SLIM goslim_pir
2008-06-09 Added SLIM goslim_generic
2008-06-09 Added SLIM goslim_candida
2008-05-13 Added DEFINITION A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
2008-05-12 Deleted DEFINITION A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
2008-04-01 Updated RELATION is a GO:0044428 (nuclear part)
2008-04-01 Updated RELATION is a GO:0043232 (intracellular non-membrane-bounded organelle)
2008-04-01 Updated RELATION part of GO:0031981 (nuclear lumen)
2002-11-27 Added DEFINITION A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
2002-02-06 Updated TERM nucleolus
2001-04-03 Updated TERM nucleolus
2001-03-30 Added TERM nucleolus

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM nucleolus
2001-04-03 Updated TERM nucleolus
2001-03-30 Added TERM nucleolus

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
2008-05-12 Deleted DEFINITION A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
2002-11-27 Added DEFINITION A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0044428 (nuclear part)
2008-04-01 Updated RELATION is a GO:0043232 (intracellular non-membrane-bounded organelle)
2008-04-01 Updated RELATION part of GO:0031981 (nuclear lumen)

Cross-references

Timestamp Action Category Detail
2010-02-04 Added XREF NIF_Subcellular:sao1820400233
2009-02-05 Added XREF Wikipedia:Nucleolus

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_aspergillus
2013-04-18 Updated SLIM goslim_yeast
2013-04-18 Updated SLIM goslim_plant
2013-04-18 Updated SLIM goslim_pir
2013-04-18 Updated SLIM goslim_generic
2013-04-18 Updated SLIM goslim_candida
2011-11-05 Added SLIM goslim_aspergillus
2008-06-09 Added SLIM goslim_yeast
2008-06-09 Added SLIM goslim_plant
2008-06-09 Added SLIM goslim_pir
2008-06-09 Added SLIM goslim_generic
2008-06-09 Added SLIM goslim_candida
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