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GO:0005681 spliceosomal complex

Term Information

ID GO:0005681
Name spliceosomal complex
Ontology Cellular Component
Definition Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.
PMID:19239890
GONUTS GO:0005681 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad spliceosome
exact spliceosome complex

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000059 GO:0005634 nucleus only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_pir462

Cross-references

Database ID
InterPro IPR004015
InterPro IPR004098
InterPro IPR004123
InterPro IPR006973
InterPro IPR017364
InterPro IPR017862
InterPro IPR026300
InterPro IPR027078
InterPro IPR027652
InterPro IPR029536
InterPro IPR031776
UniProtKB-KW Spliceosome
Wikipedia Spliceosome

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex CONSIDER GO:0005681

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005681:
Relationship To GO:0005681 Child Term Child Term Name
Is a GO:0005684 U2-type spliceosomal complex
Is a GO:0005689 U12-type spliceosomal complex
Is a GO:0044530 supraspliceosomal complex
Is a GO:0071010 prespliceosome
Is a GO:0071011 precatalytic spliceosome
Is a GO:0071012 catalytic step 1 spliceosome
Is a GO:0071013 catalytic step 2 spliceosome
Is a GO:0071014 post-mRNA release spliceosomal complex
Is a GO:0071020 post-spliceosomal complex
Is a GO:0071023 trans spliceosomal complex

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005681. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005681 based on the entire annotation set Co-occurrence statistics for GO:0005681 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2015-03-16 Added DEFINITION Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.
2015-03-16 Deleted DEFINITION Any of a series of ribonucleoprotein complexes that contain RNA and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the splicing of a messenger RNA primary transcript to excise an intron.
2013-04-18 Updated SLIM goslim_pir
2012-03-17 Added SYNONYM spliceosome
2009-08-03 Added DEFINITION Any of a series of ribonucleoprotein complexes that contain RNA and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the splicing of a messenger RNA primary transcript to excise an intron.
2009-08-03 Deleted DEFINITION A ribonucleoprotein complex, containing RNA and small nuclear ribonucleoproteins (snRNPs) that is assembled during the splicing of messenger RNA primary transcript to excise an intron.
2009-08-03 Updated TERM spliceosomal complex
2009-02-05 Added XREF Wikipedia:Spliceosome
2008-06-09 Added SLIM goslim_pir
2008-05-13 Added DEFINITION A ribonucleoprotein complex, containing RNA and small nuclear ribonucleoproteins (snRNPs) that is assembled during the splicing of messenger RNA primary transcript to excise an intron.
2008-05-12 Deleted DEFINITION A ribonucleoprotein complex, containing RNA and small nuclear ribonucleoproteins (snRNPs) that is assembled during the splicing of messenger RNA primary transcript to excise an intron.
2008-04-01 Updated RELATION is a GO:0044428 (nuclear part)
2008-04-01 Updated RELATION is a GO:0030529 (ribonucleoprotein complex)
2007-08-09 Added SYNONYM spliceosome complex
2007-08-09 Deleted SYNONYM spliceosome complex
2007-01-15 Updated TERM spliceosome
2007-01-15 Added SYNONYM spliceosome complex
2002-05-24 Updated TERM spliceosome complex
2002-02-06 Updated TERM spliceosome
2001-08-06 Added DEFINITION A ribonucleoprotein complex, containing RNA and small nuclear ribonucleoproteins (snRNPs) that is assembled during the splicing of messenger RNA primary transcript to excise an intron.
2001-04-03 Updated TERM spliceosome
2001-03-30 Added TERM spliceosome

Term

Timestamp Action Category Detail
2009-08-03 Updated TERM spliceosomal complex
2007-01-15 Updated TERM spliceosome
2002-05-24 Updated TERM spliceosome complex
2002-02-06 Updated TERM spliceosome
2001-04-03 Updated TERM spliceosome
2001-03-30 Added TERM spliceosome

Definition/synonyms

Timestamp Action Category Detail
2015-03-16 Added DEFINITION Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.
2015-03-16 Deleted DEFINITION Any of a series of ribonucleoprotein complexes that contain RNA and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the splicing of a messenger RNA primary transcript to excise an intron.
2012-03-17 Added SYNONYM spliceosome
2009-08-03 Added DEFINITION Any of a series of ribonucleoprotein complexes that contain RNA and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the splicing of a messenger RNA primary transcript to excise an intron.
2009-08-03 Deleted DEFINITION A ribonucleoprotein complex, containing RNA and small nuclear ribonucleoproteins (snRNPs) that is assembled during the splicing of messenger RNA primary transcript to excise an intron.
2008-05-13 Added DEFINITION A ribonucleoprotein complex, containing RNA and small nuclear ribonucleoproteins (snRNPs) that is assembled during the splicing of messenger RNA primary transcript to excise an intron.
2008-05-12 Deleted DEFINITION A ribonucleoprotein complex, containing RNA and small nuclear ribonucleoproteins (snRNPs) that is assembled during the splicing of messenger RNA primary transcript to excise an intron.
2007-08-09 Added SYNONYM spliceosome complex
2007-08-09 Deleted SYNONYM spliceosome complex
2007-01-15 Added SYNONYM spliceosome complex
2001-08-06 Added DEFINITION A ribonucleoprotein complex, containing RNA and small nuclear ribonucleoproteins (snRNPs) that is assembled during the splicing of messenger RNA primary transcript to excise an intron.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0044428 (nuclear part)
2008-04-01 Updated RELATION is a GO:0030529 (ribonucleoprotein complex)

Cross-references

Timestamp Action Category Detail
2009-02-05 Added XREF Wikipedia:Spliceosome

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_pir
2008-06-09 Added SLIM goslim_pir
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