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GO:0005680 anaphase-promoting complexA ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.
Term Information
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| Type | Synonym |
| exact | cyclosome |
| exact | anaphase promoting complex |
| broad | APC |
| Database | ID |
| INTERPRO | IPR004939 |
| INTERPRO | IPR007192 |
| Wikipedia | Anaphase-promoting_complex |
| INTERPRO | IPR008402 |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0005575 cellular_component | |||||||||||||||||
![]() | GO:0032991 macromolecular complex | ||||||||||||||||
![]() | ![]() | GO:0005623 cell | |||||||||||||||
![]() | ![]() | ![]() | GO:0043226 organelle | ||||||||||||||
![]() | ![]() | ![]() | ![]() | GO:0043227 membrane-bounded organelle | |||||||||||||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0044464 cell part | ||||||||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0043234 protein complex | |||||||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0044422 organelle part | ||||||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0005622 intracellular | |||||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0044424 intracellular part | ||||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0043229 intracellular organelle | |||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0000151 ubiquitin ligase complex | ||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0043231 intracellular membrane-bounded organelle | |||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0044446 intracellular organelle part | ||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0005634 nucleus | |||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0044428 nuclear part | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0000152 nuclear ubiquitin ligase complex | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0005680 anaphase-promoting complex |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-11-23-04-03-36 |