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GO:0005669 transcription factor TFIID complex

A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters.

Term Information

ID GO:0005669
Name transcription factor TFIID complex
Ontology Cellular Component
Definition A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters.
Comment

Cross-references associated with this term:

Database ID
INTERPRO IPR011177
INTERPRO IPR006751
INTERPRO IPR003228
INTERPRO IPR003162
INTERPRO IPR007900
INTERPRO IPR000814

This term can be used instead of these obsolete terms:

GO:0005670 transcription-activating factor, 30kD (replaced_by GO:0005669)

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Ancestor Table

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GO:0005575 cellular_component
GO:0032991 macromolecular complex
GO:0005623 cell
GO:0031974 membrane-enclosed lumen
GO:0043226 organelle
GO:0043227 membrane-bounded organelle
GO:0044464 cell part
GO:0043234 protein complex
GO:0044422 organelle part
GO:0005622 intracellular
GO:0043233 organelle lumen
GO:0044424 intracellular part
GO:0043229 intracellular organelle
GO:0043231 intracellular membrane-bounded organelle
GO:0044446 intracellular organelle part
GO:0005634 nucleus
GO:0070013 intracellular organelle lumen
GO:0044428 nuclear part
GO:0031981 nuclear lumen
GO:0005654 nucleoplasm
GO:0044451 nucleoplasm part
GO:0016591 DNA-directed RNA polymerase II, holoenzyme
GO:0005667 transcription factor complex
GO:0005669 transcription factor TFIID complex

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0070556 TAF4B-containing transcription factor TFIID complex

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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