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GO:0005666 DNA-directed RNA polymerase III complex

RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.

Term Information

ID GO:0005666
Name DNA-directed RNA polymerase III complex
Ontology Cellular Component
Definition RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
Comment

Synonyms

Type Synonym
related DNA-directed RNA polymerase III activity

Cross-references associated with this term:

Database ID
INTERPRO IPR007811

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Ancestor Chart

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0005575 cellular_component
GO:0043226 organelle
GO:0032991 macromolecular complex
GO:0005623 cell
GO:0031974 membrane-enclosed lumen
GO:0043227 membrane-bounded organelle
GO:0044464 cell part
GO:0043234 protein complex
GO:0044422 organelle part
GO:0005622 intracellular
GO:0043233 organelle lumen
GO:0044424 intracellular part
GO:0043229 intracellular organelle
GO:0030880 RNA polymerase complex
GO:0043231 intracellular membrane-bounded organelle
GO:0044446 intracellular organelle part
GO:0000428 DNA-directed RNA polymerase complex
GO:0055029 nuclear DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0070013 intracellular organelle lumen
GO:0044428 nuclear part
GO:0031981 nuclear lumen
GO:0005654 nucleoplasm
GO:0044451 nucleoplasm part
GO:0005666 DNA-directed RNA polymerase III complex

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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14ms
Stand-alone
Hostnametomcat-7.ebi.ac.uk
Uptime16:38 12/10/2009
Data version2009-11-24-04-03-40
Terminal
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