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GO:0005662 DNA replication factor A complex

A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa.

Term Information

ID GO:0005662
Name DNA replication factor A complex
Ontology Cellular Component
Definition A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa.
Comment

Synonyms

Type Synonym
related SSB
exact replication protein A
related single-stranded DNA-binding protein complex
exact RPA

Cross-references associated with this term:

Database ID
Wikipedia Replication_protein_A

Web service: term information

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0005575 cellular_component
GO:0032991 macromolecular complex
GO:0043226 organelle
GO:0005623 cell
GO:0043227 membrane-bounded organelle
GO:0044464 cell part
GO:0032993 protein-DNA complex
GO:0043234 protein complex
GO:0044422 organelle part
GO:0043228 non-membrane-bounded organelle
GO:0005622 intracellular
GO:0044424 intracellular part
GO:0043229 intracellular organelle
GO:0043231 intracellular membrane-bounded organelle
GO:0044446 intracellular organelle part
GO:0043232 intracellular non-membrane-bounded organelle
GO:0005634 nucleus
GO:0005694 chromosome
GO:0044427 chromosomal part
GO:0044428 nuclear part
GO:0005657 replication fork
GO:0000228 nuclear chromosome
GO:0030894 replisome
GO:0044454 nuclear chromosome part
GO:0043596 nuclear replication fork
GO:0043601 nuclear replisome
GO:0005662 DNA replication factor A complex

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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