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GO:0005658 alpha DNA polymerase:primase complex

A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which catalyzes the synthesis of an RNA primer on the lagging strand of replicating DNA; the smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.

Term Information

ID GO:0005658
Name alpha DNA polymerase:primase complex
Ontology Cellular Component
Definition A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which catalyzes the synthesis of an RNA primer on the lagging strand of replicating DNA; the smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.
Comment

Synonyms

Type Synonym
broad primosome
related pol-prim
exact DNA polymerase alpha:primase complex
exact heterotetrameric polymerase alpha holoenzyme

Cross-references associated with this term:

Database ID
INTERPRO IPR011372
INTERPRO IPR007238
INTERPRO IPR012191
INTERPRO IPR012192

Web service: term information

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Ancestor Chart

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Chart

Ancestor Table

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GO:0005575 cellular_component
GO:0043226 organelle
GO:0032991 macromolecular complex
GO:0005623 cell
GO:0032993 protein-DNA complex
GO:0043227 membrane-bounded organelle
GO:0044464 cell part
GO:0043228 non-membrane-bounded organelle
GO:0043234 protein complex
GO:0044422 organelle part
GO:0005622 intracellular
GO:0044424 intracellular part
GO:0043229 intracellular organelle
GO:0043231 intracellular membrane-bounded organelle
GO:0044446 intracellular organelle part
GO:0043232 intracellular non-membrane-bounded organelle
GO:0005694 chromosome
GO:0005634 nucleus
GO:0044427 chromosomal part
GO:0044428 nuclear part
GO:0005657 replication fork
GO:0030894 replisome
GO:0000228 nuclear chromosome
GO:0044454 nuclear chromosome part
GO:0043596 nuclear replication fork
GO:0043601 nuclear replisome
GO:0005658 alpha DNA polymerase:primase complex

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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13ms
Stand-alone
Hostnametomcat-7.ebi.ac.uk
Uptime16:38 12/10/2009
Data version2009-11-24-04-03-40
Terminal
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