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GO:0005656 nuclear pre-replicative complex

Term Information

ID GO:0005656
Name nuclear pre-replicative complex
Ontology Cellular Component
Definition A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.
PMID:15222894
GONUTS GO:0005656 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad pre-replicative complex
related pre-RC
exact eukaryotic pre-replicative complex

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000059 GO:0005634 nucleus only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005656:
Relationship To GO:0005656 Child Term Child Term Name
Has part GO:0000808 origin recognition complex
Has part GO:0042555 MCM complex

Protein Annotation

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GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005656. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005656 based on the entire annotation set Co-occurrence statistics for GO:0005656 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-06-12 Added RELATION is a GO:0036387 (pre-replicative complex)
2013-06-12 Deleted RELATION is a GO:0032993 (protein-DNA complex)
2013-06-12 Added SYNONYM eukaryotic pre-replicative complex
2013-06-12 Added SYNONYM pre-replicative complex
2013-06-12 Added SYNONYM pre-RC
2013-06-12 Deleted SYNONYM pre-RC
2013-06-12 Updated TERM nuclear pre-replicative complex
2012-06-22 Added RELATION has part GO:0031261 (DNA replication preinitiation complex)
2009-11-24 Added DEFINITION A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.
2009-11-24 Deleted DEFINITION A multiprotein complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.
2008-06-16 Added RELATION is a GO:0032993 (protein-DNA complex)
2008-06-16 Deleted RELATION is a GO:0043234 (protein complex)
2008-05-13 Added DEFINITION A multiprotein complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.
2008-05-12 Deleted DEFINITION A multiprotein complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.
2008-04-01 Updated RELATION is a GO:0044451 (nucleoplasm part)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2007-08-09 Added SYNONYM pre-RC
2007-08-09 Deleted SYNONYM pre-RC
2005-03-03 Added SYNONYM pre-RC
2004-07-29 Added DEFINITION A multiprotein complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.
2002-02-06 Updated TERM pre-replicative complex
2001-04-03 Updated TERM pre-replicative complex
2001-03-30 Added TERM pre-replicative complex

Term

Timestamp Action Category Detail
2013-06-12 Updated TERM nuclear pre-replicative complex
2002-02-06 Updated TERM pre-replicative complex
2001-04-03 Updated TERM pre-replicative complex
2001-03-30 Added TERM pre-replicative complex

Definition/synonyms

Timestamp Action Category Detail
2013-06-12 Added SYNONYM eukaryotic pre-replicative complex
2013-06-12 Added SYNONYM pre-replicative complex
2013-06-12 Added SYNONYM pre-RC
2013-06-12 Deleted SYNONYM pre-RC
2009-11-24 Added DEFINITION A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.
2009-11-24 Deleted DEFINITION A multiprotein complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.
2008-05-13 Added DEFINITION A multiprotein complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.
2008-05-12 Deleted DEFINITION A multiprotein complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.
2007-08-09 Added SYNONYM pre-RC
2007-08-09 Deleted SYNONYM pre-RC
2005-03-03 Added SYNONYM pre-RC
2004-07-29 Added DEFINITION A multiprotein complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.

Relationships

Timestamp Action Category Detail
2013-06-12 Added RELATION is a GO:0036387 (pre-replicative complex)
2013-06-12 Deleted RELATION is a GO:0032993 (protein-DNA complex)
2012-06-22 Added RELATION has part GO:0031261 (DNA replication preinitiation complex)
2008-06-16 Added RELATION is a GO:0032993 (protein-DNA complex)
2008-06-16 Deleted RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION is a GO:0044451 (nucleoplasm part)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
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