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GO:0005634 nucleus

Term Information

ID GO:0005634
Name nucleus
Ontology Cellular Component
Definition A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GONUTS GO:0005634 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact cell nucleus

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000059 GO:0005634 nucleus only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_metagenomics119
goslim_candida89
goslim_generic149
goslim_pir462
goslim_plant100
goslim_yeast169
goslim_aspergillus85

Cross-references

Database ID
InterPro IPR000003
InterPro IPR000040
InterPro IPR000079
InterPro IPR000091
InterPro IPR000116
InterPro IPR000128
InterPro IPR000197
InterPro IPR000221
InterPro IPR000232
InterPro IPR000324
InterPro IPR000451
InterPro IPR000465
InterPro IPR000492
InterPro IPR000536
InterPro IPR000558
InterPro IPR000647
InterPro IPR000678
InterPro IPR000690
InterPro IPR000747
InterPro IPR000818
InterPro IPR000967
InterPro IPR000969
InterPro IPR000972
InterPro IPR000976
InterPro IPR001044
InterPro IPR001067
InterPro IPR001083
InterPro IPR001103
InterPro IPR001138
InterPro IPR001217
InterPro IPR001292
InterPro IPR001319
InterPro IPR001321
InterPro IPR001409
InterPro IPR001628
InterPro IPR001630
InterPro IPR001699
InterPro IPR001723
InterPro IPR001728
InterPro IPR001739
InterPro IPR001748
InterPro IPR001945
InterPro IPR001951
InterPro IPR002070
InterPro IPR002117
InterPro IPR002119
InterPro IPR002164
InterPro IPR002344
InterPro IPR002409
InterPro IPR002418
InterPro IPR002487
InterPro IPR002515
InterPro IPR002546
InterPro IPR002652
InterPro IPR002691
InterPro IPR002706
InterPro IPR002717
InterPro IPR002719
InterPro IPR002720
InterPro IPR003011
InterPro IPR003021
InterPro IPR003022
InterPro IPR003025
InterPro IPR003026
InterPro IPR003027
InterPro IPR003068
InterPro IPR003069
InterPro IPR003070
InterPro IPR003071
InterPro IPR003072
InterPro IPR003073
InterPro IPR003074
InterPro IPR003075
InterPro IPR003076
InterPro IPR003077
InterPro IPR003078
InterPro IPR003079
InterPro IPR003106
InterPro IPR003118
InterPro IPR003120
InterPro IPR003153
InterPro IPR003175
InterPro IPR003309
InterPro IPR003311
InterPro IPR003327
InterPro IPR003380
InterPro IPR003415
InterPro IPR003417
InterPro IPR003545
InterPro IPR003606
InterPro IPR003617
InterPro IPR003822
InterPro IPR003888
InterPro IPR003889
InterPro IPR003893
InterPro IPR003923
InterPro IPR003956
InterPro IPR004023
InterPro IPR004092
InterPro IPR004162
InterPro IPR004321
InterPro IPR004333
InterPro IPR004343
InterPro IPR004367
InterPro IPR004575
InterPro IPR004579
InterPro IPR004580
InterPro IPR004582
InterPro IPR004583
InterPro IPR004591
InterPro IPR004598
InterPro IPR004806
InterPro IPR004823
InterPro IPR004826
InterPro IPR004865
InterPro IPR004871
InterPro IPR004979
InterPro IPR005033
InterPro IPR005314
InterPro IPR005539
InterPro IPR005540
InterPro IPR005541
InterPro IPR005542
InterPro IPR005559
InterPro IPR005571
InterPro IPR005637
InterPro IPR005818
InterPro IPR006165
InterPro IPR006289
InterPro IPR006509
InterPro IPR006529
InterPro IPR006536
InterPro IPR006560
InterPro IPR006711
InterPro IPR006712
InterPro IPR006715
InterPro IPR006730
InterPro IPR006762
InterPro IPR006773
InterPro IPR006774
InterPro IPR006779
InterPro IPR006794
InterPro IPR006809
InterPro IPR006811
InterPro IPR006818
InterPro IPR006820
InterPro IPR006856
InterPro IPR006886
InterPro IPR006897
InterPro IPR006898
InterPro IPR006899
InterPro IPR006940
InterPro IPR006941
InterPro IPR006942
InterPro IPR006957
InterPro IPR006986
InterPro IPR006988
InterPro IPR006989
InterPro IPR007005
InterPro IPR007010
InterPro IPR007023
InterPro IPR007071
InterPro IPR007086
InterPro IPR007180
InterPro IPR007199
InterPro IPR007207
InterPro IPR007218
InterPro IPR007219
InterPro IPR007220
InterPro IPR007257
InterPro IPR007281
InterPro IPR007282
InterPro IPR007576
InterPro IPR007582
InterPro IPR007591
InterPro IPR007668
InterPro IPR007673
InterPro IPR007728
InterPro IPR007738
InterPro IPR007747
InterPro IPR008013
InterPro IPR008045
InterPro IPR008046
InterPro IPR008048
InterPro IPR008049
InterPro IPR008050
InterPro IPR008087
InterPro IPR008111
InterPro IPR008121
InterPro IPR008122
InterPro IPR008123
InterPro IPR008251
InterPro IPR008288
InterPro IPR008468
InterPro IPR008676
InterPro IPR008685
InterPro IPR008847
InterPro IPR008851
InterPro IPR008888
InterPro IPR008895
InterPro IPR008955
InterPro IPR009089
InterPro IPR009110
InterPro IPR009145
InterPro IPR009146
InterPro IPR009170
InterPro IPR009287
InterPro IPR009349
InterPro IPR009361
InterPro IPR009422
InterPro IPR009464
InterPro IPR009511
InterPro IPR009524
InterPro IPR009668
InterPro IPR009674
InterPro IPR009800
InterPro IPR010003
InterPro IPR010011
InterPro IPR010304
InterPro IPR010347
InterPro IPR010405
InterPro IPR010491
InterPro IPR010506
InterPro IPR010519
InterPro IPR010525
InterPro IPR010531
InterPro IPR010533
InterPro IPR010542
InterPro IPR010578
InterPro IPR010585
InterPro IPR010643
InterPro IPR010678
InterPro IPR010684
InterPro IPR011236
InterPro IPR011364
InterPro IPR011381
InterPro IPR011420
InterPro IPR011442
InterPro IPR011494
InterPro IPR011515
InterPro IPR011520
InterPro IPR011539
InterPro IPR011940
InterPro IPR011943
InterPro IPR011947
InterPro IPR012099
InterPro IPR012173
InterPro IPR012270
InterPro IPR012313
InterPro IPR012345
InterPro IPR012346
InterPro IPR012423
InterPro IPR012532
InterPro IPR012541
InterPro IPR012542
InterPro IPR012562
InterPro IPR012572
InterPro IPR012579
InterPro IPR012580
InterPro IPR012582
InterPro IPR012584
InterPro IPR012587
InterPro IPR012617
InterPro IPR012890
InterPro IPR012900
InterPro IPR012916
InterPro IPR012920
InterPro IPR012923
InterPro IPR012934
InterPro IPR012935
InterPro IPR012948
InterPro IPR012957
InterPro IPR012958
InterPro IPR012982
InterPro IPR013697
InterPro IPR013700
InterPro IPR013800
InterPro IPR013801
InterPro IPR013851
InterPro IPR013868
InterPro IPR013970
InterPro IPR014402
InterPro IPR014492
InterPro IPR014612
InterPro IPR014646
InterPro IPR014744
InterPro IPR014789
InterPro IPR014891
InterPro IPR014920
InterPro IPR014978
InterPro IPR015021
InterPro IPR015115
InterPro IPR015195
InterPro IPR015245
InterPro IPR015270
InterPro IPR015311
InterPro IPR015350
InterPro IPR015351
InterPro IPR015381
InterPro IPR015408
InterPro IPR015699
InterPro IPR015700
InterPro IPR015877
InterPro IPR016256
InterPro IPR016266
InterPro IPR016325
InterPro IPR016376
InterPro IPR016487
InterPro IPR016495
InterPro IPR016527
InterPro IPR016588
InterPro IPR016640
InterPro IPR016679
InterPro IPR016686
InterPro IPR016743
InterPro IPR016819
InterPro IPR016899
InterPro IPR017074
InterPro IPR017151
InterPro IPR017164
InterPro IPR017198
InterPro IPR017253
InterPro IPR017335
InterPro IPR017336
InterPro IPR017357
InterPro IPR017366
InterPro IPR017380
InterPro IPR017890
InterPro IPR017923
InterPro IPR017967
InterPro IPR017995
InterPro IPR018121
InterPro IPR018144
InterPro IPR018186
InterPro IPR018230
InterPro IPR018287
InterPro IPR018324
InterPro IPR018325
InterPro IPR018465
InterPro IPR018472
InterPro IPR018554
InterPro IPR018574
InterPro IPR018944
InterPro IPR019015
InterPro IPR019024
InterPro IPR019038
InterPro IPR019041
InterPro IPR019809
InterPro IPR020062
InterPro IPR020186
InterPro IPR020448
InterPro IPR020604
InterPro IPR020793
InterPro IPR020796
InterPro IPR020993
InterPro IPR021162
InterPro IPR021169
InterPro IPR021171
InterPro IPR022312
InterPro IPR022783
InterPro IPR023278
InterPro IPR024178
InterPro IPR024193
InterPro IPR024318
InterPro IPR024741
InterPro IPR024786
InterPro IPR024824
InterPro IPR024830
InterPro IPR024872
InterPro IPR024874
InterPro IPR024876
InterPro IPR024931
InterPro IPR025848
InterPro IPR026052
InterPro IPR026153
InterPro IPR026201
InterPro IPR026216
InterPro IPR026306
InterPro IPR026314
InterPro IPR026607
InterPro IPR026621
InterPro IPR026632
InterPro IPR026638
InterPro IPR026649
InterPro IPR026668
InterPro IPR026678
InterPro IPR026745
InterPro IPR026753
InterPro IPR026784
InterPro IPR026810
InterPro IPR026817
InterPro IPR026836
InterPro IPR026936
InterPro IPR026943
InterPro IPR027011
InterPro IPR027086
InterPro IPR027107
InterPro IPR027218
InterPro IPR027249
InterPro IPR027289
InterPro IPR027678
InterPro IPR027709
InterPro IPR027722
InterPro IPR027729
InterPro IPR027755
InterPro IPR027756
InterPro IPR027757
InterPro IPR027758
InterPro IPR027759
InterPro IPR027767
InterPro IPR027775
InterPro IPR027784
InterPro IPR027786
InterPro IPR027976
InterPro IPR027998
InterPro IPR028128
InterPro IPR028317
InterPro IPR028363
InterPro IPR028372
InterPro IPR028376
InterPro IPR028400
InterPro IPR028432
InterPro IPR028434
InterPro IPR028436
InterPro IPR028437
InterPro IPR028440
InterPro IPR028444
InterPro IPR028466
InterPro IPR028562
InterPro IPR028571
InterPro IPR028573
InterPro IPR028574
InterPro IPR028575
InterPro IPR028638
InterPro IPR028639
InterPro IPR028643
InterPro IPR028647
InterPro IPR028651
InterPro IPR028721
InterPro IPR028773
InterPro IPR028782
InterPro IPR028785
InterPro IPR029136
InterPro IPR029138
InterPro IPR029163
InterPro IPR029289
InterPro IPR029293
InterPro IPR029518
InterPro IPR029521
InterPro IPR029522
InterPro IPR029524
InterPro IPR029547
InterPro IPR029548
InterPro IPR029564
InterPro IPR029671
InterPro IPR029682
InterPro IPR029699
InterPro IPR029700
InterPro IPR029708
InterPro IPR029732
InterPro IPR029750
InterPro IPR029780
InterPro IPR029788
InterPro IPR029790
InterPro IPR029791
InterPro IPR029794
InterPro IPR029795
InterPro IPR029796
InterPro IPR029798
InterPro IPR029801
InterPro IPR029802
InterPro IPR029803
InterPro IPR029819
InterPro IPR029829
InterPro IPR029830
InterPro IPR029832
InterPro IPR029836
InterPro IPR029859
InterPro IPR029992
InterPro IPR030006
InterPro IPR030008
InterPro IPR030017
InterPro IPR030019
InterPro IPR030054
InterPro IPR030080
InterPro IPR030101
InterPro IPR030271
NIF_Subcellular sao1702920020
UniProtKB-KW Nucleus
UniProtKB-SubCell Nucleus
Wikipedia Cell_nucleus

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0005645 RAN-binding protein CONSIDER GO:0005634
GO:0005646 importin CONSIDER GO:0005634
GO:0005647 importin, alpha-subunit CONSIDER GO:0005634
GO:0005648 importin, beta-subunit CONSIDER GO:0005634
GO:0005649 transportin CONSIDER GO:0005634
GO:0005650 importin, alpha-subunit transport factor CONSIDER GO:0005634
GO:0005651 exportin CONSIDER GO:0005634

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005634:
Relationship To GO:0005634 Child Term Child Term Name
Is a GO:0043076 megasporocyte nucleus
Is a GO:0048556 microsporocyte nucleus
Is a GO:0031039 macronucleus
Is a GO:0031040 micronucleus
Is a GO:0043073 germ cell nucleus
Is a GO:0045120 pronucleus
Is a GO:0048353 primary endosperm nucleus
Is a GO:0048555 generative cell nucleus
Part of GO:0044428 nuclear part
Is a GO:0071686 horsetail nucleus
Part of GO:1990453 nucleosome disassembly/reassembly complex
Is a GO:0098537 lobed nucleus
Is a GO:0097571 left nucleus
Is a GO:0097572 right nucleus
Occurs in GO:1902375 nuclear tRNA 3'-trailer cleavage, endonucleolytic
Part of GO:1902377 nuclear rDNA heterochromatin
Part of GO:1990433 CSL-Notch-Mastermind transcription factor complex
Part of GO:1990378 upstream stimulatory factor complex

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005634. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005634 based on the entire annotation set Co-occurrence statistics for GO:0005634 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_aspergillus
2013-04-18 Updated SLIM goslim_yeast
2013-04-18 Updated SLIM goslim_plant
2013-04-18 Updated SLIM goslim_pir
2013-04-18 Updated SLIM goslim_generic
2013-04-18 Updated SLIM goslim_candida
2013-04-18 Updated SLIM goslim_metagenomics
2012-02-17 Added SLIM goslim_metagenomics
2011-11-05 Added SLIM goslim_aspergillus
2011-03-18 Deleted SLIM goslim_goa
2010-02-04 Added XREF NIF_Subcellular:sao1702920020
2009-02-05 Added XREF Wikipedia:Cell_nucleus
2008-08-04 Added SYNONYM cell nucleus
2008-06-09 Added SLIM goslim_yeast
2008-06-09 Added SLIM goslim_plant
2008-06-09 Added SLIM goslim_pir
2008-06-09 Added SLIM goslim_goa
2008-06-09 Added SLIM goslim_generic
2008-06-09 Added SLIM goslim_candida
2008-05-13 Added DEFINITION A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2008-05-12 Deleted DEFINITION A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2008-04-01 Updated RELATION is a GO:0043231 (intracellular membrane-bounded organelle)
2005-08-18 Deleted SYNONYM RAN-binding protein
2005-08-18 Deleted SYNONYM exportin
2005-08-18 Deleted SYNONYM importin
2005-08-18 Deleted SYNONYM importin, alpha-subunit
2005-08-18 Deleted SYNONYM importin, alpha-subunit transport factor
2005-08-18 Deleted SYNONYM importin, beta-subunit
2005-08-18 Deleted SYNONYM transportin
2005-08-10 Added SYNONYM importin, alpha-subunit transport factor
2005-08-10 Added SYNONYM importin, beta-subunit
2005-08-10 Added SYNONYM transportin
2005-08-10 Added SYNONYM RAN-binding protein
2005-08-10 Added SYNONYM exportin
2005-08-10 Added SYNONYM importin
2005-08-10 Added SYNONYM importin, alpha-subunit
2004-10-08 Updated DEFINITION A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2004-09-29 Updated TERM nucleus
2002-11-27 Updated DEFINITION A membrane-bounded organelle of eukaryotic cells that contains the chromosomes. It is the primary site of DNA replication and RNA synthesis in the cell.
2002-02-06 Updated TERM nucleus
2001-08-06 Added DEFINITION An organelle of eukaryotic cells that contains the chromosomes. Except for the mitochondria it is the sole site of DNA replication and RNA synthesis in the cell.
2001-04-03 Updated TERM nucleus
2001-03-30 Added TERM nucleus

Term

Timestamp Action Category Detail
2004-09-29 Updated TERM nucleus
2002-02-06 Updated TERM nucleus
2001-04-03 Updated TERM nucleus
2001-03-30 Added TERM nucleus

Definition/synonyms

Timestamp Action Category Detail
2008-08-04 Added SYNONYM cell nucleus
2008-05-13 Added DEFINITION A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2008-05-12 Deleted DEFINITION A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2005-08-18 Deleted SYNONYM RAN-binding protein
2005-08-18 Deleted SYNONYM exportin
2005-08-18 Deleted SYNONYM importin
2005-08-18 Deleted SYNONYM importin, alpha-subunit
2005-08-18 Deleted SYNONYM importin, alpha-subunit transport factor
2005-08-18 Deleted SYNONYM importin, beta-subunit
2005-08-18 Deleted SYNONYM transportin
2005-08-10 Added SYNONYM importin, alpha-subunit transport factor
2005-08-10 Added SYNONYM importin, beta-subunit
2005-08-10 Added SYNONYM transportin
2005-08-10 Added SYNONYM RAN-binding protein
2005-08-10 Added SYNONYM exportin
2005-08-10 Added SYNONYM importin
2005-08-10 Added SYNONYM importin, alpha-subunit
2004-10-08 Updated DEFINITION A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2002-11-27 Updated DEFINITION A membrane-bounded organelle of eukaryotic cells that contains the chromosomes. It is the primary site of DNA replication and RNA synthesis in the cell.
2001-08-06 Added DEFINITION An organelle of eukaryotic cells that contains the chromosomes. Except for the mitochondria it is the sole site of DNA replication and RNA synthesis in the cell.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0043231 (intracellular membrane-bounded organelle)

Cross-references

Timestamp Action Category Detail
2010-02-04 Added XREF NIF_Subcellular:sao1702920020
2009-02-05 Added XREF Wikipedia:Cell_nucleus

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_aspergillus
2013-04-18 Updated SLIM goslim_yeast
2013-04-18 Updated SLIM goslim_plant
2013-04-18 Updated SLIM goslim_pir
2013-04-18 Updated SLIM goslim_generic
2013-04-18 Updated SLIM goslim_candida
2013-04-18 Updated SLIM goslim_metagenomics
2012-02-17 Added SLIM goslim_metagenomics
2011-11-05 Added SLIM goslim_aspergillus
2011-03-18 Deleted SLIM goslim_goa
2008-06-09 Added SLIM goslim_yeast
2008-06-09 Added SLIM goslim_plant
2008-06-09 Added SLIM goslim_pir
2008-06-09 Added SLIM goslim_goa
2008-06-09 Added SLIM goslim_generic
2008-06-09 Added SLIM goslim_candida
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