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GO:0005578 proteinaceous extracellular matrix

Term Information

ID GO:0005578
Name proteinaceous extracellular matrix
Ontology Cellular Component
Definition A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. An example of this component is found in Mus musculus.
GONUTS GO:0005578 Wiki Page

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000056 GO:0005578 proteinaceous extracellular matrix only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_generic149
goslim_plant100

Cross-references

Database ID
InterPro IPR001863
InterPro IPR003979
InterPro IPR004116
InterPro IPR009437
InterPro IPR011398
InterPro IPR012011
InterPro IPR013273
InterPro IPR013274
InterPro IPR013275
InterPro IPR013276
InterPro IPR013277
InterPro IPR016359
InterPro IPR019577
InterPro IPR019803
InterPro IPR027215
InterPro IPR027216
InterPro IPR027219
InterPro IPR028492
InterPro IPR028735
InterPro IPR028736
UniProtKB-KW Extracellular matrix
UniProtKB-SubCell Extracellular matrix

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0030022 adhesive extracellular matrix constituent REPLACEDBY GO:0005578

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005578:
Relationship To GO:0005578 Child Term Child Term Name
Part of GO:0043205 fibril
Part of GO:0005604 basement membrane
Is a GO:0060102 collagen and cuticulin-based cuticle extracellular matrix
Is a GO:0033165 interphotoreceptor matrix
Is a GO:0033166 hyaline layer
Is a GO:0005614 interstitial matrix
Part of GO:0005583 fibrillar collagen trimer
Part of GO:0030934 anchoring collagen complex
Part of GO:0030935 sheet-forming collagen trimer
Part of GO:1990324 collagen type XXVI trimer
Part of GO:1990325 collagen type XXVII trimer
Part of GO:1990326 collagen type XXVIII trimer

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
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GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
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Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005578. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005578 based on the entire annotation set Co-occurrence statistics for GO:0005578 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_plant
2013-04-18 Updated SLIM goslim_generic
2012-03-17 Added RELATION is a GO:0044421 (extracellular region part)
2011-03-18 Deleted SLIM goslim_goa
2009-07-11 Deleted SYNONYM extracellular matrix (sensu Metazoa)
2009-07-11 Added DEFINITION A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. An example of this component is found in Mus musculus.
2009-07-11 Deleted DEFINITION A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.
2008-07-11 Deleted RELATION is a GO:0044421 (extracellular region part)
2008-06-09 Added SLIM goslim_plant
2008-06-09 Added SLIM goslim_goa
2008-06-09 Added SLIM goslim_generic
2008-05-13 Added DEFINITION A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.
2008-05-12 Deleted DEFINITION A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.
2008-04-01 Updated RELATION is a GO:0044421 (extracellular region part)
2008-04-01 Updated RELATION is a GO:0031012 (extracellular matrix)
2007-10-08 Deleted SYNONYM adhesive extracellular matrix constituent
2007-08-09 Added SYNONYM adhesive extracellular matrix constituent
2007-08-09 Added SYNONYM extracellular matrix (sensu Metazoa)
2007-08-09 Deleted SYNONYM extracellular matrix (sensu Metazoa)
2007-08-09 Deleted SYNONYM adhesive extracellular matrix constituent
2007-04-20 Updated DEFINITION A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.
2007-02-16 Updated DEFINITION A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.
2007-02-12 Added SYNONYM extracellular matrix (sensu Metazoa)
2007-02-12 Updated TERM proteinaceous extracellular matrix
2007-01-18 Updated TERM extracellular matrix (sensu Metazoa)
2007-01-15 Updated TERM extracellular matrix (sensu the Metazoa research community)
2005-08-10 Added SYNONYM adhesive extracellular matrix constituent
2004-09-29 Updated TERM extracellular matrix (sensu Metazoa)
2004-09-20 Updated TERM extracellular matrix (sensu Metazoa)
2004-09-19 Updated DEFINITION A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208).
2004-09-16 Updated TERM extracellular matrix (sensu Animalia)
2002-02-06 Updated TERM extracellular matrix
2001-08-06 Added DEFINITION A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.
2001-04-03 Updated TERM extracellular matrix
2001-03-30 Added TERM extracellular matrix

Term

Timestamp Action Category Detail
2007-02-12 Updated TERM proteinaceous extracellular matrix
2007-01-18 Updated TERM extracellular matrix (sensu Metazoa)
2007-01-15 Updated TERM extracellular matrix (sensu the Metazoa research community)
2004-09-29 Updated TERM extracellular matrix (sensu Metazoa)
2004-09-20 Updated TERM extracellular matrix (sensu Metazoa)
2004-09-16 Updated TERM extracellular matrix (sensu Animalia)
2002-02-06 Updated TERM extracellular matrix
2001-04-03 Updated TERM extracellular matrix
2001-03-30 Added TERM extracellular matrix

Definition/synonyms

Timestamp Action Category Detail
2009-07-11 Deleted SYNONYM extracellular matrix (sensu Metazoa)
2009-07-11 Added DEFINITION A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. An example of this component is found in Mus musculus.
2009-07-11 Deleted DEFINITION A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.
2008-05-13 Added DEFINITION A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.
2008-05-12 Deleted DEFINITION A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.
2007-10-08 Deleted SYNONYM adhesive extracellular matrix constituent
2007-08-09 Added SYNONYM adhesive extracellular matrix constituent
2007-08-09 Added SYNONYM extracellular matrix (sensu Metazoa)
2007-08-09 Deleted SYNONYM extracellular matrix (sensu Metazoa)
2007-08-09 Deleted SYNONYM adhesive extracellular matrix constituent
2007-04-20 Updated DEFINITION A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.
2007-02-16 Updated DEFINITION A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.
2007-02-12 Added SYNONYM extracellular matrix (sensu Metazoa)
2005-08-10 Added SYNONYM adhesive extracellular matrix constituent
2004-09-19 Updated DEFINITION A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208).
2001-08-06 Added DEFINITION A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.

Relationships

Timestamp Action Category Detail
2012-03-17 Added RELATION is a GO:0044421 (extracellular region part)
2008-07-11 Deleted RELATION is a GO:0044421 (extracellular region part)
2008-04-01 Updated RELATION is a GO:0044421 (extracellular region part)
2008-04-01 Updated RELATION is a GO:0031012 (extracellular matrix)

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_plant
2013-04-18 Updated SLIM goslim_generic
2011-03-18 Deleted SLIM goslim_goa
2008-06-09 Added SLIM goslim_plant
2008-06-09 Added SLIM goslim_goa
2008-06-09 Added SLIM goslim_generic
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