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GO:0005577 fibrinogen complex

Term Information

ID GO:0005577
Name fibrinogen complex
Ontology Cellular Component
Definition A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.
GONUTS GO:0005577 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact fibrinogen
narrow fibrinogen beta chain
narrow fibrinogen gamma chain
narrow fibrinogen alpha chain

Protein complexes

Database ID Name
IntAct fibrinogen_human Fibrinogen

Cross-references

Database ID
InterPro IPR012290

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0005972 obsolete fibrinogen alpha chain CONSIDER GO:0005577
GO:0005973 obsolete fibrinogen beta chain CONSIDER GO:0005577
GO:0005974 obsolete fibrinogen gamma chain CONSIDER GO:0005577
GO:0008001 obsolete fibrinogen REPLACEDBY GO:0005577

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005577:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005577. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005577 based on the entire annotation set Co-occurrence statistics for GO:0005577 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-05-13 Added DEFINITION A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.
2008-05-12 Deleted DEFINITION A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.
2008-04-01 Updated RELATION is a GO:0044421 (extracellular region part)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION part of GO:0005615 (extracellular space)
2007-08-09 Added SYNONYM fibrinogen
2007-08-09 Added SYNONYM fibrinogen alpha chain
2007-08-09 Added SYNONYM fibrinogen beta chain
2007-08-09 Added SYNONYM fibrinogen gamma chain
2007-08-09 Deleted SYNONYM fibrinogen
2007-08-09 Deleted SYNONYM fibrinogen alpha chain
2007-08-09 Deleted SYNONYM fibrinogen beta chain
2007-08-09 Deleted SYNONYM fibrinogen gamma chain
2005-08-10 Added SYNONYM fibrinogen
2005-08-10 Added SYNONYM fibrinogen alpha chain
2005-08-10 Added SYNONYM fibrinogen beta chain
2005-08-10 Added SYNONYM fibrinogen gamma chain
2003-04-24 Updated DEFINITION A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.
2003-03-26 Updated DEFINITION A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of non-identical chains (alpha, beta, and gamma) linked together by disulfide bonds.
2002-12-14 Updated TERM fibrinogen complex
2002-11-27 Updated DEFINITION A highly soluble elongated protein from blood plasma concerned in clot formation. It is converted into fibrin monomer by the action of thrombin. Fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of non-identical chains (alpha, beta, and gamma) linked together by disulfide bonds (mouse).
2002-02-06 Updated TERM fibrinogen
2001-08-06 Added DEFINITION A highly soluble elongated protein from blood plasma concerned in clot formation. It is converted into fibrin monomer by the action of thrombin. Fibrinogen in a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (&agr;, &bgr;, and &ggr;) linked together by disulfide bonds (mouse).
2001-04-03 Updated TERM fibrinogen
2001-03-30 Added TERM fibrinogen

Term

Timestamp Action Category Detail
2002-12-14 Updated TERM fibrinogen complex
2002-02-06 Updated TERM fibrinogen
2001-04-03 Updated TERM fibrinogen
2001-03-30 Added TERM fibrinogen

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.
2008-05-12 Deleted DEFINITION A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.
2007-08-09 Added SYNONYM fibrinogen
2007-08-09 Added SYNONYM fibrinogen alpha chain
2007-08-09 Added SYNONYM fibrinogen beta chain
2007-08-09 Added SYNONYM fibrinogen gamma chain
2007-08-09 Deleted SYNONYM fibrinogen
2007-08-09 Deleted SYNONYM fibrinogen alpha chain
2007-08-09 Deleted SYNONYM fibrinogen beta chain
2007-08-09 Deleted SYNONYM fibrinogen gamma chain
2005-08-10 Added SYNONYM fibrinogen
2005-08-10 Added SYNONYM fibrinogen alpha chain
2005-08-10 Added SYNONYM fibrinogen beta chain
2005-08-10 Added SYNONYM fibrinogen gamma chain
2003-04-24 Updated DEFINITION A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.
2003-03-26 Updated DEFINITION A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of non-identical chains (alpha, beta, and gamma) linked together by disulfide bonds.
2002-11-27 Updated DEFINITION A highly soluble elongated protein from blood plasma concerned in clot formation. It is converted into fibrin monomer by the action of thrombin. Fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of non-identical chains (alpha, beta, and gamma) linked together by disulfide bonds (mouse).
2001-08-06 Added DEFINITION A highly soluble elongated protein from blood plasma concerned in clot formation. It is converted into fibrin monomer by the action of thrombin. Fibrinogen in a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (&agr;, &bgr;, and &ggr;) linked together by disulfide bonds (mouse).

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0044421 (extracellular region part)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION part of GO:0005615 (extracellular space)
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