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GO:0005577 fibrinogen complex

A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.

Term Information

ID GO:0005577
Name fibrinogen complex
Ontology Cellular Component
Definition A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.
Comment

Synonyms

Type Synonym
narrow fibrinogen gamma chain
exact fibrinogen
narrow fibrinogen alpha chain
narrow fibrinogen beta chain

Cross-references associated with this term:

Database ID
INTERPRO IPR012290
INTERPRO IPR018991
INTERPRO IPR018986

This term can be used instead of these obsolete terms:

GO:0005972 fibrinogen alpha chain (consider GO:0005577)
GO:0005973 fibrinogen beta chain (consider GO:0005577)
GO:0008001 fibrinogen (replaced_by GO:0005577)
GO:0005974 fibrinogen gamma chain (consider GO:0005577)

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Ancestor Table

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GO:0005575 cellular_component
GO:0005576 extracellular region
GO:0032991 macromolecular complex
GO:0044421 extracellular region part
GO:0043234 protein complex
GO:0005615 extracellular space
GO:0005577 fibrinogen complex

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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