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GO:0005388 calcium-transporting ATPase activity

Term Information

ID GO:0005388
Name calcium-transporting ATPase activity
Ontology Molecular Function
Definition Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans).
GONUTS GO:0005388 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow calcium-translocating P-type ATPase activity
broad calcium pump
exact Ca2+-transporting ATPase activity
exact Ca2+-pumping ATPase activity
exact ATP phosphohydrolase (Ca2+-transporting)
narrow plasma membrane Ca-ATPase
exact calcium transporting ATPase activity
narrow calcium ABC transporter
narrow calcium efflux ATPase
exact Ca(2+)-transporting ATPase activity
narrow sarco(endo)plasmic reticulum Ca2+-ATPase
narrow sarcoplasmic reticulum ATPase

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 3.6.3.8
InterPro IPR005782
InterPro IPR006408
InterPro IPR006413
InterPro IPR022141
InterPro IPR030319
InterPro IPR030320
InterPro IPR030322
InterPro IPR030325
InterPro IPR030327
InterPro IPR030330
InterPro IPR030332
InterPro IPR030334
InterPro IPR030336
MetaCyc 3.6.3.8-RXN
RHEA 18108

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005388:
Relationship To GO:0005388 Child Term Child Term Name
Regulates GO:1901894 regulation of calcium-transporting ATPase activity
Negatively regulates GO:1901895 negative regulation of calcium-transporting ATPase activity
Positively regulates GO:1901896 positive regulation of calcium-transporting ATPase activity
Is a GO:0086039 calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
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Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005388. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005388 based on the entire annotation set Co-occurrence statistics for GO:0005388 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:18108
2010-06-09 Updated TERM calcium-transporting ATPase activity
2010-06-08 Updated TERM calcium-transporting ATPase activity
2008-05-13 Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans).
2008-05-12 Deleted DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans).
2008-04-01 Updated RELATION is a GO:0015662 (ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism)
2008-04-01 Updated RELATION is a GO:0015085 (calcium ion transmembrane transporter activity)
2008-04-01 Updated RELATION is a GO:0019829 (cation-transporting ATPase activity)
2007-11-08 Added SYNONYM ATP phosphohydrolase (Ca2+-transporting)
2007-11-08 Added SYNONYM Ca2+-pumping ATPase activity
2007-11-08 Added SYNONYM Ca2+-transporting ATPase activity
2007-11-08 Added SYNONYM plasma membrane Ca-ATPase
2007-11-08 Added SYNONYM sarco(endo)plasmic reticulum Ca2+-ATPase
2007-09-06 Added SYNONYM Ca(2+)-transporting ATPase activity
2007-09-06 Added SYNONYM calcium-translocating P-type ATPase activity
2007-08-09 Added SYNONYM calcium ABC transporter
2007-08-09 Added SYNONYM calcium efflux ATPase
2007-08-09 Added SYNONYM calcium pump
2007-08-09 Added SYNONYM calcium transporting ATPase activity
2007-08-09 Added SYNONYM sarcoplasmic reticulum ATPase
2007-08-09 Deleted SYNONYM calcium transporting ATPase activity
2007-08-09 Deleted SYNONYM sarcoplasmic reticulum ATPase
2007-08-09 Deleted SYNONYM calcium ABC transporter
2007-08-09 Deleted SYNONYM calcium efflux ATPase
2007-08-09 Deleted SYNONYM calcium pump
2007-07-27 Updated DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans).
2007-07-11 Deleted XREF TC:3.A.3.2.3
2007-07-11 Deleted XREF TC:3.A.3.2.1
2005-07-29 Added SYNONYM calcium transporting ATPase activity
2005-06-12 Added SYNONYM calcium ABC transporter
2004-04-19 Added SYNONYM calcium pump
2004-04-19 Added SYNONYM sarcoplasmic reticulum ATPase
2004-04-19 Added SYNONYM calcium efflux ATPase
2004-04-16 Deleted SYNONYM calcium efflux ATPase
2004-04-16 Deleted SYNONYM calcium pump
2004-04-16 Deleted SYNONYM sarcoplasmic reticulum ATPase
2003-10-27 Added SYNONYM calcium efflux ATPase
2003-10-27 Added SYNONYM calcium pump
2003-10-27 Added SYNONYM sarcoplasmic reticulum ATPase
2003-10-27 Added XREF TC:3.A.3.2.3
2003-10-27 Added XREF TC:3.A.3.2.1
2003-10-27 Added XREF MetaCyc:3.6.3.8-RXN
2003-08-21 Deleted XREF TC:3.A.3.2.3
2003-08-21 Deleted SYNONYM calcium efflux ATPase
2003-08-21 Deleted SYNONYM calcium pump
2003-08-21 Deleted SYNONYM sarcoplasmic reticulum ATPase
2003-08-21 Deleted XREF TC:3.A.3.2.1
2003-03-26 Updated DEFINITION Catalysis of the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans).
2003-03-19 Updated TERM calcium-transporting ATPase activity
2002-11-27 Updated DEFINITION A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This enzyme family comprises three types of calcium ion-transporting enzymes that are found in the plasma membrane, the sarcoplasmic reticulum and in yeast. The first and third transport one ion per ATP hydrolyzed, whereas the second transports two ions.
2002-02-06 Updated TERM calcium-transporting ATPase
2001-08-06 Added DEFINITION A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This enzyme family comprises three types of calcium ion-transporting enzymes that are found in the plasma membrane, the sarcoplasmic reticulum and in yeast. The first and third transport one ion per ATP hydrolysed, whereas the second transports two ions.
2001-04-03 Updated TERM calcium-transporting ATPase
2001-03-30 Added XREF TC:3.A.3.2.3
2001-03-30 Added XREF TC:3.A.3.2.1
2001-03-30 Added XREF EC:3.6.3.8
2001-03-30 Added SYNONYM calcium efflux ATPase
2001-03-30 Added SYNONYM calcium pump
2001-03-30 Added SYNONYM sarcoplasmic reticulum ATPase
2001-03-30 Added TERM calcium-transporting ATPase

Term

Timestamp Action Category Detail
2010-06-09 Updated TERM calcium-transporting ATPase activity
2010-06-08 Updated TERM calcium-transporting ATPase activity
2003-03-19 Updated TERM calcium-transporting ATPase activity
2002-02-06 Updated TERM calcium-transporting ATPase
2001-04-03 Updated TERM calcium-transporting ATPase
2001-03-30 Added TERM calcium-transporting ATPase

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans).
2008-05-12 Deleted DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans).
2007-11-08 Added SYNONYM ATP phosphohydrolase (Ca2+-transporting)
2007-11-08 Added SYNONYM Ca2+-pumping ATPase activity
2007-11-08 Added SYNONYM Ca2+-transporting ATPase activity
2007-11-08 Added SYNONYM plasma membrane Ca-ATPase
2007-11-08 Added SYNONYM sarco(endo)plasmic reticulum Ca2+-ATPase
2007-09-06 Added SYNONYM Ca(2+)-transporting ATPase activity
2007-09-06 Added SYNONYM calcium-translocating P-type ATPase activity
2007-08-09 Added SYNONYM calcium ABC transporter
2007-08-09 Added SYNONYM calcium efflux ATPase
2007-08-09 Added SYNONYM calcium pump
2007-08-09 Added SYNONYM calcium transporting ATPase activity
2007-08-09 Added SYNONYM sarcoplasmic reticulum ATPase
2007-08-09 Deleted SYNONYM calcium transporting ATPase activity
2007-08-09 Deleted SYNONYM sarcoplasmic reticulum ATPase
2007-08-09 Deleted SYNONYM calcium ABC transporter
2007-08-09 Deleted SYNONYM calcium efflux ATPase
2007-08-09 Deleted SYNONYM calcium pump
2007-07-27 Updated DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans).
2005-07-29 Added SYNONYM calcium transporting ATPase activity
2005-06-12 Added SYNONYM calcium ABC transporter
2004-04-19 Added SYNONYM calcium pump
2004-04-19 Added SYNONYM sarcoplasmic reticulum ATPase
2004-04-19 Added SYNONYM calcium efflux ATPase
2004-04-16 Deleted SYNONYM calcium efflux ATPase
2004-04-16 Deleted SYNONYM calcium pump
2004-04-16 Deleted SYNONYM sarcoplasmic reticulum ATPase
2003-10-27 Added SYNONYM calcium efflux ATPase
2003-10-27 Added SYNONYM calcium pump
2003-10-27 Added SYNONYM sarcoplasmic reticulum ATPase
2003-08-21 Deleted SYNONYM calcium efflux ATPase
2003-08-21 Deleted SYNONYM calcium pump
2003-08-21 Deleted SYNONYM sarcoplasmic reticulum ATPase
2003-03-26 Updated DEFINITION Catalysis of the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans).
2002-11-27 Updated DEFINITION A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This enzyme family comprises three types of calcium ion-transporting enzymes that are found in the plasma membrane, the sarcoplasmic reticulum and in yeast. The first and third transport one ion per ATP hydrolyzed, whereas the second transports two ions.
2001-08-06 Added DEFINITION A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This enzyme family comprises three types of calcium ion-transporting enzymes that are found in the plasma membrane, the sarcoplasmic reticulum and in yeast. The first and third transport one ion per ATP hydrolysed, whereas the second transports two ions.
2001-03-30 Added SYNONYM calcium efflux ATPase
2001-03-30 Added SYNONYM calcium pump
2001-03-30 Added SYNONYM sarcoplasmic reticulum ATPase

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0015662 (ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism)
2008-04-01 Updated RELATION is a GO:0015085 (calcium ion transmembrane transporter activity)
2008-04-01 Updated RELATION is a GO:0019829 (cation-transporting ATPase activity)

Cross-references

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:18108
2007-07-11 Deleted XREF TC:3.A.3.2.3
2007-07-11 Deleted XREF TC:3.A.3.2.1
2003-10-27 Added XREF TC:3.A.3.2.3
2003-10-27 Added XREF TC:3.A.3.2.1
2003-10-27 Added XREF MetaCyc:3.6.3.8-RXN
2003-08-21 Deleted XREF TC:3.A.3.2.3
2003-08-21 Deleted XREF TC:3.A.3.2.1
2001-03-30 Added XREF TC:3.A.3.2.3
2001-03-30 Added XREF TC:3.A.3.2.1
2001-03-30 Added XREF EC:3.6.3.8
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