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GO:0005254 chloride channel activity

Term Information

ID GO:0005254
Name chloride channel activity
Ontology Molecular Function
Definition Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
GONUTS GO:0005254 Wiki Page

Cross-Ontology Relations

Relation Other Ontology ID Term
transports_or_maintains_localization_of CHEBI CHEBI:17996 chloride

Cross-references

Database ID
InterPro IPR009147
InterPro IPR030253
InterPro IPR030259
InterPro IPR030261
InterPro IPR030264
InterPro IPR030306
InterPro IPR033041
UniProtKB-KW Chloride channel

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005254:
Relationship To GO:0005254 Child Term Child Term Name
Is a GO:0005260 intracellular ATPase-gated chloride channel activity
Regulates GO:0017081 chloride channel regulator activity
Negatively regulates GO:0019869 chloride channel inhibitor activity
Is a GO:0072320 volume-sensitive chloride channel activity
Is a GO:0061778 intracellular chloride channel activity
Is a GO:0061797 pH-gated chloride channel activity
Is a GO:0005247 voltage-gated chloride channel activity
Capable of GO:0034707 chloride channel complex
Is a GO:0022851 GABA-gated chloride ion channel activity
Is a GO:0022852 glycine-gated chloride ion channel activity
Is a GO:0008068 extracellular-glutamate-gated chloride channel activity
Is a GO:0016934 extracellular-glycine-gated chloride channel activity
Is a GO:0019182 histamine-gated chloride channel activity

Protein Annotation

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GO Term Name
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Original GO ID
Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005254. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005254 based on the entire annotation set Co-occurrence statistics for GO:0005254 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2016-01-10 Added DEFINITION Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2016-01-10 Deleted SYNONYM chloride-specific channel activity
2016-01-10 Deleted DEFINITION Enables the selective, facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2015-05-19 Added SYNONYM chloride-specific channel activity
2015-05-19 Added DEFINITION Enables the selective, facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2015-05-19 Deleted DEFINITION Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2015-05-11 Deleted DEFINITION Catalysis of facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2015-05-11 Added DEFINITION Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2013-10-30 Deleted RELATION part of GO:0006821 (chloride transport)
2013-10-23 Deleted XREF RHEA:29826
2012-09-14 Added XREF RHEA:29826
2012-06-01 Added RELATION is a GO:0015108 (chloride transmembrane transporter activity)
2010-06-15 Added RELATION part of GO:0006821 (chloride transport)
2010-06-14 Deleted RELATION part of GO:0006821 (chloride transport)
2010-06-09 Updated TERM chloride channel activity
2010-06-08 Updated TERM chloride channel activity
2010-06-08 Added RELATION part of GO:0006821 (chloride transport)
2008-08-17 Added DEFINITION Catalysis of facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2008-08-17 Deleted DEFINITION Catalysis of facilitated diffusion of an chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2008-05-13 Added DEFINITION Catalysis of facilitated diffusion of an chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2008-05-12 Deleted DEFINITION Catalysis of facilitated diffusion of an chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2008-04-01 Updated RELATION is a GO:0005253 (anion channel activity)
2007-07-27 Added DEFINITION Catalysis of facilitated diffusion of an chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2003-03-19 Updated TERM chloride channel activity
2002-02-06 Updated TERM chloride channel
2001-04-03 Updated TERM chloride channel
2001-03-30 Added TERM chloride channel

Term

Timestamp Action Category Detail
2010-06-09 Updated TERM chloride channel activity
2010-06-08 Updated TERM chloride channel activity
2003-03-19 Updated TERM chloride channel activity
2002-02-06 Updated TERM chloride channel
2001-04-03 Updated TERM chloride channel
2001-03-30 Added TERM chloride channel

Definition/synonyms

Timestamp Action Category Detail
2016-01-10 Added DEFINITION Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2016-01-10 Deleted SYNONYM chloride-specific channel activity
2016-01-10 Deleted DEFINITION Enables the selective, facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2015-05-19 Added SYNONYM chloride-specific channel activity
2015-05-19 Added DEFINITION Enables the selective, facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2015-05-19 Deleted DEFINITION Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2015-05-11 Deleted DEFINITION Catalysis of facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2015-05-11 Added DEFINITION Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2008-08-17 Added DEFINITION Catalysis of facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2008-08-17 Deleted DEFINITION Catalysis of facilitated diffusion of an chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2008-05-13 Added DEFINITION Catalysis of facilitated diffusion of an chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2008-05-12 Deleted DEFINITION Catalysis of facilitated diffusion of an chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2007-07-27 Added DEFINITION Catalysis of facilitated diffusion of an chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

Relationships

Timestamp Action Category Detail
2013-10-30 Deleted RELATION part of GO:0006821 (chloride transport)
2012-06-01 Added RELATION is a GO:0015108 (chloride transmembrane transporter activity)
2010-06-15 Added RELATION part of GO:0006821 (chloride transport)
2010-06-14 Deleted RELATION part of GO:0006821 (chloride transport)
2010-06-08 Added RELATION part of GO:0006821 (chloride transport)
2008-04-01 Updated RELATION is a GO:0005253 (anion channel activity)

Cross-references

Timestamp Action Category Detail
2013-10-23 Deleted XREF RHEA:29826
2012-09-14 Added XREF RHEA:29826
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