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GO:0005123 death receptor binding

Interacting selectively and non-covalently with any member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD).

Term Information

ID GO:0005123
Name death receptor binding
Ontology Molecular Function
Definition Interacting selectively and non-covalently with any member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD).
Comment

Synonyms

Type Synonym
narrow TNFR1 binding
narrow TRAIL binding
related death receptor-associated factor activity
narrow NGFR binding
narrow KILLER binding
narrow FAS binding
narrow EDAR binding
narrow death receptor ligand
narrow APO binding
narrow DR binding
related death receptor interacting protein activity
related death receptor adaptor protein activity

This term can be used instead of these obsolete terms:

GO:0005038 death receptor interacting protein activity (consider GO:0005123)
GO:0005039 death receptor-associated factor activity (consider GO:0005123)
GO:0005037 death receptor adaptor protein activity (consider GO:0005123)

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Ancestor Chart

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Ancestor Table

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GO:0003674 molecular_function
GO:0005488 binding
GO:0005515 protein binding
GO:0005102 receptor binding
GO:0005126 cytokine receptor binding
GO:0032813 tumor necrosis factor receptor superfamily binding
GO:0005123 death receptor binding

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0005163 nerve growth factor receptor binding

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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