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GO:0005096 GTPase activator activity

Term Information

ID GO:0005096
Name GTPase activator activity
Ontology Molecular Function
Definition Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
Comment Note that the name Sar derives from 'secretion-associated, Ras-related'.
Secondary IDs GO:0005097 GO:0005098 GO:0005099 GO:0005100 GO:0005101 GO:0008060 GO:0017123 GO:0030675 GO:0046582
GONUTS GO:0005096 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow Rab GTPase activator activity
narrow Rab GAP activity
narrow Ran GTPase activator activity
narrow Ral GTPase activator activity
exact GAP activity
narrow Rho GTPase activator activity
narrow Sar GTPase activator activity
narrow ARF GAP activity
narrow Ras GAP activity
narrow Ras GTPase activator activity
narrow Rho GAP activity
narrow ARF GTPase activator activity
narrow Rac GAP activity
narrow Rac GTPase activator activity
narrow Rap GTPase activator activity
narrow Ran GAP activity
narrow Sar GAP activity
narrow Ral GAP activity
narrow Rap GAP activity
narrow RanGAP

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
InterPro IPR000331
InterPro IPR000593
InterPro IPR001164
InterPro IPR003537
InterPro IPR003913
InterPro IPR003914
InterPro IPR009109
InterPro IPR015123
InterPro IPR017332
InterPro IPR018514
InterPro IPR018515
InterPro IPR026147
InterPro IPR026817
InterPro IPR027038
InterPro IPR027107
InterPro IPR028553
InterPro IPR028554
InterPro IPR028557
InterPro IPR028558
InterPro IPR028775
InterPro IPR028854
InterPro IPR029645
InterPro IPR029880
InterPro IPR029882
InterPro IPR030061
InterPro IPR030403
InterPro IPR030409
InterPro IPR030717
InterPro IPR030722
InterPro IPR030724
InterPro IPR030731
InterPro IPR030739
InterPro IPR030770
InterPro IPR030772
InterPro IPR030776
InterPro IPR031214
UniProtKB-KW GTPase activation

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005096:
Relationship To GO:0005096 Child Term Child Term Name
Capable of GO:1902773 GTPase activator complex

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005096. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005096 based on the entire annotation set Co-occurrence statistics for GO:0005096 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2015-07-11 Added DEFINITION Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
2015-07-11 Deleted DEFINITION Increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
2015-02-13 Added SYNONYM ARF GTPase activator activity
2015-02-13 Added SYNONYM Rac GAP activity
2015-02-13 Added SYNONYM Rac GTPase activator activity
2015-02-13 Added SYNONYM Rap GTPase activator activity
2015-02-13 Added SYNONYM Rho GTPase activator activity
2015-02-13 Added SYNONYM Ral GTPase activator activity
2015-02-13 Added SYNONYM Ran GAP activity
2015-02-13 Added SYNONYM Ran GTPase activator activity
2015-02-13 Added SYNONYM Rab GAP activity
2015-02-13 Added SYNONYM Rab GTPase activator activity
2015-02-13 Added SYNONYM RanGAP
2015-02-13 Added SYNONYM Rap GAP activity
2015-02-13 Added SYNONYM Sar GAP activity
2015-02-13 Added SYNONYM Ral GAP activity
2015-02-13 Added SYNONYM ARF GAP activity
2015-02-13 Added SYNONYM Ras GAP activity
2015-02-13 Added SYNONYM Ras GTPase activator activity
2015-02-13 Added SYNONYM Rho GAP activity
2015-02-13 Added SYNONYM Sar GTPase activator activity
2015-02-13 Added SECONDARY GO:0046582 (Rap GTPase activator activity)
2015-02-13 Added SECONDARY GO:0030675 (Rac GTPase activator activity)
2015-02-13 Added SECONDARY GO:0017123 (Ral GTPase activator activity)
2015-02-13 Added SECONDARY GO:0008060 (ARF GTPase activator activity)
2015-02-13 Added SECONDARY GO:0005101 (Sar GTPase activator activity)
2015-02-13 Added SECONDARY GO:0005100 (Rho GTPase activator activity)
2015-02-13 Added SECONDARY GO:0005099 (Ras GTPase activator activity)
2015-02-13 Added SECONDARY GO:0005098 (Ran GTPase activator activity)
2015-02-13 Added SECONDARY GO:0005097 (Rab GTPase activator activity)
2011-03-10 Added RELATION part of GO:0043547 (positive regulation of GTPase activity)
2010-06-15 Added RELATION positively regulates GO:0003924 (GTPase activity)
2010-06-14 Deleted RELATION positively regulates GO:0003924 (GTPase activity)
2010-06-08 Added RELATION positively regulates GO:0003924 (GTPase activity)
2009-02-25 Deleted RELATION positively regulates GO:0003924 (GTPase activity)
2009-02-22 Added RELATION positively regulates GO:0003924 (GTPase activity)
2008-10-02 Added SYNONYM GAP activity
2008-10-02 Deleted SYNONYM GAP
2008-05-13 Added DEFINITION Increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
2008-05-12 Deleted DEFINITION Increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
2008-04-01 Updated RELATION is a GO:0008047 (enzyme activator activity)
2008-04-01 Updated RELATION is a GO:0030695 (GTPase regulator activity)
2007-08-09 Added SYNONYM GAP
2007-08-09 Deleted SYNONYM GAP
2004-04-19 Added SYNONYM GAP
2004-04-16 Deleted SYNONYM GAP
2004-01-08 Updated DEFINITION Increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
2003-04-25 Added DEFINITION Increases the rate of GTP hydrolysis by a GTPase.
2003-03-19 Updated TERM GTPase activator activity
2002-02-06 Updated TERM GTPase activator
2001-04-03 Updated TERM GTPase activator
2001-03-30 Added SYNONYM GAP
2001-03-30 Added TERM GTPase activator

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM GTPase activator activity
2002-02-06 Updated TERM GTPase activator
2001-04-03 Updated TERM GTPase activator
2001-03-30 Added TERM GTPase activator

Definition/synonyms

Timestamp Action Category Detail
2015-07-11 Added DEFINITION Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
2015-07-11 Deleted DEFINITION Increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
2015-02-13 Added SYNONYM ARF GTPase activator activity
2015-02-13 Added SYNONYM Rac GAP activity
2015-02-13 Added SYNONYM Rac GTPase activator activity
2015-02-13 Added SYNONYM Rap GTPase activator activity
2015-02-13 Added SYNONYM Rho GTPase activator activity
2015-02-13 Added SYNONYM Ral GTPase activator activity
2015-02-13 Added SYNONYM Ran GAP activity
2015-02-13 Added SYNONYM Ran GTPase activator activity
2015-02-13 Added SYNONYM Rab GAP activity
2015-02-13 Added SYNONYM Rab GTPase activator activity
2015-02-13 Added SYNONYM RanGAP
2015-02-13 Added SYNONYM Rap GAP activity
2015-02-13 Added SYNONYM Sar GAP activity
2015-02-13 Added SYNONYM Ral GAP activity
2015-02-13 Added SYNONYM ARF GAP activity
2015-02-13 Added SYNONYM Ras GAP activity
2015-02-13 Added SYNONYM Ras GTPase activator activity
2015-02-13 Added SYNONYM Rho GAP activity
2015-02-13 Added SYNONYM Sar GTPase activator activity
2008-10-02 Added SYNONYM GAP activity
2008-10-02 Deleted SYNONYM GAP
2008-05-13 Added DEFINITION Increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
2008-05-12 Deleted DEFINITION Increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
2007-08-09 Added SYNONYM GAP
2007-08-09 Deleted SYNONYM GAP
2004-04-19 Added SYNONYM GAP
2004-04-16 Deleted SYNONYM GAP
2004-01-08 Updated DEFINITION Increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
2003-04-25 Added DEFINITION Increases the rate of GTP hydrolysis by a GTPase.
2001-03-30 Added SYNONYM GAP

Relationships

Timestamp Action Category Detail
2011-03-10 Added RELATION part of GO:0043547 (positive regulation of GTPase activity)
2010-06-15 Added RELATION positively regulates GO:0003924 (GTPase activity)
2010-06-14 Deleted RELATION positively regulates GO:0003924 (GTPase activity)
2010-06-08 Added RELATION positively regulates GO:0003924 (GTPase activity)
2009-02-25 Deleted RELATION positively regulates GO:0003924 (GTPase activity)
2009-02-22 Added RELATION positively regulates GO:0003924 (GTPase activity)
2008-04-01 Updated RELATION is a GO:0008047 (enzyme activator activity)
2008-04-01 Updated RELATION is a GO:0030695 (GTPase regulator activity)

Other

Timestamp Action Category Detail
2015-02-13 Added SECONDARY GO:0046582 (Rap GTPase activator activity)
2015-02-13 Added SECONDARY GO:0030675 (Rac GTPase activator activity)
2015-02-13 Added SECONDARY GO:0017123 (Ral GTPase activator activity)
2015-02-13 Added SECONDARY GO:0008060 (ARF GTPase activator activity)
2015-02-13 Added SECONDARY GO:0005101 (Sar GTPase activator activity)
2015-02-13 Added SECONDARY GO:0005100 (Rho GTPase activator activity)
2015-02-13 Added SECONDARY GO:0005099 (Ras GTPase activator activity)
2015-02-13 Added SECONDARY GO:0005098 (Ran GTPase activator activity)
2015-02-13 Added SECONDARY GO:0005097 (Rab GTPase activator activity)
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