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GO:0005089 Rho guanyl-nucleotide exchange factor activityStimulates the exchange of guanyl nucleotides by a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
Term Information
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| Type | Synonym |
| exact | Rho guanine nucleotide exchange factor |
| exact | RhoGEF |
| Database | ID |
| INTERPRO | IPR000219 |
| INTERPRO | IPR005512 |
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| GO:0003674 molecular_function | |||||||
![]() | GO:0030234 enzyme regulator activity | ||||||
![]() | ![]() | GO:0060589 nucleoside-triphosphatase regulator activity | |||||
![]() | ![]() | ![]() | GO:0030695 GTPase regulator activity | ||||
![]() | ![]() | ![]() | ![]() | GO:0005085 guanyl-nucleotide exchange factor activity | |||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0005083 small GTPase regulator activity | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0005088 Ras guanyl-nucleotide exchange factor activity | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0005089 Rho guanyl-nucleotide exchange factor activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| I | GO:0030676 Rac guanyl-nucleotide exchange factor activity |
| Code | Relationship |
| P | part of |
| I | is a |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-11-22-04-02-35 |