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GO:0005086 ARF guanyl-nucleotide exchange factor activity

Stimulates the exchange of guanyl nucleotides by the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.

Term Information

ID GO:0005086
Name ARF guanyl-nucleotide exchange factor activity
Ontology Molecular Function
Definition Stimulates the exchange of guanyl nucleotides by the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
Comment

Cross-references associated with this term:

Database ID
INTERPRO IPR000904

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Ancestor Table

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GO:0003674 molecular_function
GO:0030234 enzyme regulator activity
GO:0060589 nucleoside-triphosphatase regulator activity
GO:0030695 GTPase regulator activity
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005083 small GTPase regulator activity
GO:0005086 ARF guanyl-nucleotide exchange factor activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

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Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
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Taxonomy
From
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Co-occurring Terms

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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