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GO:0005024 transforming growth factor beta-activated receptor activity

Term Information

ID GO:0005024
Name transforming growth factor beta-activated receptor activity
Ontology Molecular Function
Definition Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
Comment Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand TGFbeta. For binding to other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.
GONUTS GO:0005024 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact TGFbetaR
exact TGFbeta receptor activity
exact TGF-beta receptor activity
exact TGFbeta-activated receptor activity
exact transforming growth factor beta receptor activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005024:
Relationship To GO:0005024 Child Term Child Term Name
Is a GO:0005025 transforming growth factor beta receptor activity, type I
Is a GO:0005026 transforming growth factor beta receptor activity, type II
Capable of GO:0070022 transforming growth factor beta receptor homodimeric complex
Is a GO:0070123 transforming growth factor beta receptor activity, type III

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
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Taxon
Date
Assigned By
Product Form ID
Name
Synonym
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005024. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005024 based on the entire annotation set Co-occurrence statistics for GO:0005024 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-02-05 Deleted DEFINITION Combining with transforming growth factor beta to initiate a change in cell activity.
2012-02-05 Added DEFINITION Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
2011-08-18 Updated TERM transforming growth factor beta-activated receptor activity
2011-08-18 Added SYNONYM transforming growth factor beta receptor activity
2011-08-18 Added SYNONYM TGFbeta-activated receptor activity
2008-05-13 Added DEFINITION Combining with transforming growth factor beta to initiate a change in cell activity.
2008-05-12 Deleted DEFINITION Combining with transforming growth factor beta to initiate a change in cell activity.
2008-04-01 Updated RELATION is a GO:0004675 (transmembrane receptor protein serine/threonine kinase activity)
2007-08-09 Added SYNONYM TGF-beta receptor activity
2007-08-09 Added SYNONYM TGFbeta receptor activity
2007-08-09 Added SYNONYM TGFbetaR
2007-08-09 Deleted SYNONYM TGFbeta receptor activity
2007-08-09 Deleted SYNONYM TGFbetaR
2007-08-09 Deleted SYNONYM TGF-beta receptor activity
2005-03-22 Added DEFINITION Combining with transforming growth factor beta to initiate a change in cell activity.
2004-04-19 Added SYNONYM TGF-beta receptor activity
2004-04-19 Added SYNONYM TGFbeta receptor activity
2004-04-19 Added SYNONYM TGFbetaR
2004-04-16 Deleted SYNONYM TGF-beta receptor activity
2004-04-16 Deleted SYNONYM TGFbeta receptor activity
2004-04-16 Deleted SYNONYM TGFbetaR
2004-01-22 Updated TERM transforming growth factor beta receptor activity
2004-01-22 Added SYNONYM TGFbeta receptor activity
2003-08-30 Added SYNONYM TGF-beta receptor activity
2003-03-19 Updated TERM transforming growth factor-beta receptor activity
2002-02-06 Updated TERM transforming growth factor-beta receptor
2002-01-10 Updated TERM transforming growth factor-beta receptor
2001-04-03 Updated TERM transforming growth factor beta receptor
2001-03-30 Added SYNONYM TGFbetaR
2001-03-30 Added TERM transforming growth factor beta receptor

Term

Timestamp Action Category Detail
2011-08-18 Updated TERM transforming growth factor beta-activated receptor activity
2004-01-22 Updated TERM transforming growth factor beta receptor activity
2003-03-19 Updated TERM transforming growth factor-beta receptor activity
2002-02-06 Updated TERM transforming growth factor-beta receptor
2002-01-10 Updated TERM transforming growth factor-beta receptor
2001-04-03 Updated TERM transforming growth factor beta receptor
2001-03-30 Added TERM transforming growth factor beta receptor

Definition/synonyms

Timestamp Action Category Detail
2012-02-05 Deleted DEFINITION Combining with transforming growth factor beta to initiate a change in cell activity.
2012-02-05 Added DEFINITION Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
2011-08-18 Added SYNONYM transforming growth factor beta receptor activity
2011-08-18 Added SYNONYM TGFbeta-activated receptor activity
2008-05-13 Added DEFINITION Combining with transforming growth factor beta to initiate a change in cell activity.
2008-05-12 Deleted DEFINITION Combining with transforming growth factor beta to initiate a change in cell activity.
2007-08-09 Added SYNONYM TGF-beta receptor activity
2007-08-09 Added SYNONYM TGFbeta receptor activity
2007-08-09 Added SYNONYM TGFbetaR
2007-08-09 Deleted SYNONYM TGFbeta receptor activity
2007-08-09 Deleted SYNONYM TGFbetaR
2007-08-09 Deleted SYNONYM TGF-beta receptor activity
2005-03-22 Added DEFINITION Combining with transforming growth factor beta to initiate a change in cell activity.
2004-04-19 Added SYNONYM TGF-beta receptor activity
2004-04-19 Added SYNONYM TGFbeta receptor activity
2004-04-19 Added SYNONYM TGFbetaR
2004-04-16 Deleted SYNONYM TGF-beta receptor activity
2004-04-16 Deleted SYNONYM TGFbeta receptor activity
2004-04-16 Deleted SYNONYM TGFbetaR
2004-01-22 Added SYNONYM TGFbeta receptor activity
2003-08-30 Added SYNONYM TGF-beta receptor activity
2001-03-30 Added SYNONYM TGFbetaR

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004675 (transmembrane receptor protein serine/threonine kinase activity)
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