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GO:0005021 vascular endothelial growth factor-activated receptor activity

Term Information

ID GO:0005021
Name vascular endothelial growth factor-activated receptor activity
Ontology Molecular Function
Definition Combining with a vascular endothelial growth factor (VEGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity.
Comment Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand VEGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.
GONUTS GO:0005021 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact vascular endothelial growth factor receptor activity
exact VEGF-activated receptor activity
exact VEGF receptor activity
exact VEGFR activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0001010 GO:0070848 response to growth factor never_in_taxon 2, 2157, 4751 Fungi or Bacteria or Archaea
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR009135
InterPro IPR009136
InterPro IPR009137
InterPro IPR014648
InterPro IPR027143
InterPro IPR027146

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005021:
Relationship To GO:0005021 Child Term Child Term Name
Has part GO:0038085 vascular endothelial growth factor binding
Is a GO:0036326 VEGF-A-activated receptor activity
Is a GO:0036327 VEGF-B-activated receptor activity
Is a GO:0036328 VEGF-C-activated receptor activity
Is a GO:0036329 VEGF-D-activated receptor activity
Is a GO:0036330 VEGF-E-activated receptor activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0005021. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0005021 based on the entire annotation set Co-occurrence statistics for GO:0005021 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-08-03 Added RELATION has part GO:0038190 (VEGF-activated neuropilin signaling pathway)
2013-08-03 Added RELATION has part GO:0038086 (VEGF-activated platelet-derived growth factor receptor signaling pathway)
2012-02-03 Added RELATION part of GO:0038084 (vascular endothelial growth factor signaling pathway)
2012-02-03 Deleted RELATION part of GO:0048010 (vascular endothelial growth factor receptor signaling pathway)
2012-02-03 Deleted DEFINITION Combining with vascular endothelial growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
2012-02-03 Added DEFINITION Combining with a vascular endothelial growth factor (VEGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity.
2011-08-18 Updated TERM vascular endothelial growth factor-activated receptor activity
2011-08-18 Added SYNONYM VEGF-activated receptor activity
2011-08-18 Added SYNONYM vascular endothelial growth factor receptor activity
2011-08-18 Added DEFINITION Combining with vascular endothelial growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
2011-08-18 Deleted DEFINITION Combining with vascular endothelial growth factor to initiate a change in cell activity.
2010-06-15 Added RELATION part of GO:0048010 (vascular endothelial growth factor receptor signaling pathway)
2010-06-14 Deleted RELATION part of GO:0048010 (vascular endothelial growth factor receptor signaling pathway)
2010-06-09 Updated TERM vascular endothelial growth factor receptor activity
2010-06-08 Added RELATION part of GO:0048010 (vascular endothelial growth factor receptor signaling pathway)
2010-06-08 Updated TERM vascular endothelial growth factor receptor activity
2010-03-26 Added SYNONYM VEGF receptor activity
2010-03-26 Added SYNONYM VEGFR activity
2008-05-13 Added DEFINITION Combining with vascular endothelial growth factor to initiate a change in cell activity.
2008-05-12 Deleted DEFINITION Combining with vascular endothelial growth factor to initiate a change in cell activity.
2008-04-01 Updated RELATION is a GO:0004714 (transmembrane receptor protein tyrosine kinase activity)
2005-03-22 Added DEFINITION Combining with vascular endothelial growth factor to initiate a change in cell activity.
2003-03-19 Updated TERM vascular endothelial growth factor receptor activity
2002-02-06 Updated TERM vascular endothelial growth factor receptor
2001-04-03 Updated TERM vascular endothelial growth factor receptor
2001-03-30 Added TERM vascular endothelial growth factor receptor

Term

Timestamp Action Category Detail
2011-08-18 Updated TERM vascular endothelial growth factor-activated receptor activity
2010-06-09 Updated TERM vascular endothelial growth factor receptor activity
2010-06-08 Updated TERM vascular endothelial growth factor receptor activity
2003-03-19 Updated TERM vascular endothelial growth factor receptor activity
2002-02-06 Updated TERM vascular endothelial growth factor receptor
2001-04-03 Updated TERM vascular endothelial growth factor receptor
2001-03-30 Added TERM vascular endothelial growth factor receptor

Definition/synonyms

Timestamp Action Category Detail
2012-02-03 Deleted DEFINITION Combining with vascular endothelial growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
2012-02-03 Added DEFINITION Combining with a vascular endothelial growth factor (VEGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity.
2011-08-18 Added SYNONYM VEGF-activated receptor activity
2011-08-18 Added SYNONYM vascular endothelial growth factor receptor activity
2011-08-18 Added DEFINITION Combining with vascular endothelial growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
2011-08-18 Deleted DEFINITION Combining with vascular endothelial growth factor to initiate a change in cell activity.
2010-03-26 Added SYNONYM VEGF receptor activity
2010-03-26 Added SYNONYM VEGFR activity
2008-05-13 Added DEFINITION Combining with vascular endothelial growth factor to initiate a change in cell activity.
2008-05-12 Deleted DEFINITION Combining with vascular endothelial growth factor to initiate a change in cell activity.
2005-03-22 Added DEFINITION Combining with vascular endothelial growth factor to initiate a change in cell activity.

Relationships

Timestamp Action Category Detail
2013-08-03 Added RELATION has part GO:0038190 (VEGF-activated neuropilin signaling pathway)
2013-08-03 Added RELATION has part GO:0038086 (VEGF-activated platelet-derived growth factor receptor signaling pathway)
2012-02-03 Added RELATION part of GO:0038084 (vascular endothelial growth factor signaling pathway)
2012-02-03 Deleted RELATION part of GO:0048010 (vascular endothelial growth factor receptor signaling pathway)
2010-06-15 Added RELATION part of GO:0048010 (vascular endothelial growth factor receptor signaling pathway)
2010-06-14 Deleted RELATION part of GO:0048010 (vascular endothelial growth factor receptor signaling pathway)
2010-06-08 Added RELATION part of GO:0048010 (vascular endothelial growth factor receptor signaling pathway)
2008-04-01 Updated RELATION is a GO:0004714 (transmembrane receptor protein tyrosine kinase activity)
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