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GO:0004993 serotonin receptor activity

Term Information

ID GO:0004993
Name serotonin receptor activity
Ontology Molecular Function
Definition Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.
Secondary IDs GO:0001585 GO:0016609
GONUTS GO:0004993 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact 5-HT receptor
exact G protein coupled serotonin receptor activity
exact 5-hydroxytryptamine receptor
exact G-protein coupled serotonin receptor activity
exact G-protein-coupled serotonin receptor activity

Cross-Ontology Relations

Relation Other Ontology ID Term
has_input CHEBI CHEBI:28790 serotonin

Cross-references

Database ID
InterPro IPR000377
InterPro IPR000431
InterPro IPR000450
InterPro IPR000455
InterPro IPR000482
InterPro IPR000505
InterPro IPR000610
InterPro IPR001069
InterPro IPR001397
InterPro IPR001520
InterPro IPR002147
InterPro IPR002231
InterPro IPR002232
InterPro IPR027425
Wikipedia 5-HT_receptor

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004993:
Relationship To GO:0004993 Child Term Child Term Name
Is a GO:0001586 Gi/o-coupled serotonin receptor activity
Is a GO:0001587 Gq/11-coupled serotonin receptor activity
Has part GO:0051378 serotonin binding

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004993. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004993 based on the entire annotation set Co-occurrence statistics for GO:0004993 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-11-16 Deleted DEFINITION Combining with the biogenic amine serotonin, a neurotransmitter and hormone found in vertebrates, invertebrates and plants, to initiate a change in cell activity.
2011-11-16 Added DEFINITION Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.
2011-06-12 Added RELATION part of GO:0007210 (serotonin receptor signaling pathway)
2010-10-07 Added SYNONYM G-protein coupled serotonin receptor activity
2010-10-07 Added SYNONYM G-protein-coupled serotonin receptor activity
2010-10-07 Added SECONDARY GO:0016609 (G-protein coupled serotonin receptor activity)
2010-10-07 Added SYNONYM G protein coupled serotonin receptor activity
2010-06-09 Updated TERM serotonin receptor activity
2010-06-08 Updated TERM serotonin receptor activity
2009-02-25 Added XREF Wikipedia:5-HT_receptor
2008-05-13 Added DEFINITION Combining with the biogenic amine serotonin, a neurotransmitter and hormone found in vertebrates, invertebrates and plants, to initiate a change in cell activity.
2008-05-12 Deleted DEFINITION Combining with the biogenic amine serotonin, a neurotransmitter and hormone found in vertebrates, invertebrates and plants, to initiate a change in cell activity.
2008-04-01 Updated RELATION is a GO:0008227 (G-protein coupled amine receptor activity)
2007-08-09 Added SYNONYM 5-HT receptor
2007-08-09 Added SYNONYM 5-hydroxytryptamine receptor
2007-08-09 Deleted SYNONYM 5-HT receptor
2007-08-09 Deleted SYNONYM 5-hydroxytryptamine receptor
2004-04-19 Added SYNONYM 5-HT receptor
2004-04-19 Added SYNONYM 5-hydroxytryptamine receptor
2004-04-16 Deleted SYNONYM 5-HT receptor
2004-04-16 Deleted SYNONYM 5-hydroxytryptamine receptor
2004-01-03 Updated DEFINITION Combining with the biogenic amine serotonin, a neurotransmitter and hormone found in vertebrates, invertebrates and plants, to initiate a change in cell activity.
2003-05-13 Added DEFINITION The function of combining with the biogenic amine serotonin, a neurotransmitter and hormone found in vertebrates, invertebrates and plants, to initiate a change in cell function.
2003-03-19 Updated TERM serotonin receptor activity
2003-03-19 Deleted SYNONYM 5HT receptor
2002-10-19 Added SECONDARY GO:0001585 (5-hydroxytryptamine receptor)
2002-10-19 Added SYNONYM 5-HT receptor
2002-02-06 Updated TERM serotonin receptor
2001-04-03 Updated TERM serotonin receptor
2001-03-30 Added SYNONYM 5-hydroxytryptamine receptor
2001-03-30 Added SYNONYM 5HT receptor
2001-03-30 Added TERM serotonin receptor

Term

Timestamp Action Category Detail
2010-06-09 Updated TERM serotonin receptor activity
2010-06-08 Updated TERM serotonin receptor activity
2003-03-19 Updated TERM serotonin receptor activity
2002-02-06 Updated TERM serotonin receptor
2001-04-03 Updated TERM serotonin receptor
2001-03-30 Added TERM serotonin receptor

Definition/synonyms

Timestamp Action Category Detail
2011-11-16 Deleted DEFINITION Combining with the biogenic amine serotonin, a neurotransmitter and hormone found in vertebrates, invertebrates and plants, to initiate a change in cell activity.
2011-11-16 Added DEFINITION Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.
2010-10-07 Added SYNONYM G-protein coupled serotonin receptor activity
2010-10-07 Added SYNONYM G-protein-coupled serotonin receptor activity
2010-10-07 Added SYNONYM G protein coupled serotonin receptor activity
2008-05-13 Added DEFINITION Combining with the biogenic amine serotonin, a neurotransmitter and hormone found in vertebrates, invertebrates and plants, to initiate a change in cell activity.
2008-05-12 Deleted DEFINITION Combining with the biogenic amine serotonin, a neurotransmitter and hormone found in vertebrates, invertebrates and plants, to initiate a change in cell activity.
2007-08-09 Added SYNONYM 5-HT receptor
2007-08-09 Added SYNONYM 5-hydroxytryptamine receptor
2007-08-09 Deleted SYNONYM 5-HT receptor
2007-08-09 Deleted SYNONYM 5-hydroxytryptamine receptor
2004-04-19 Added SYNONYM 5-HT receptor
2004-04-19 Added SYNONYM 5-hydroxytryptamine receptor
2004-04-16 Deleted SYNONYM 5-HT receptor
2004-04-16 Deleted SYNONYM 5-hydroxytryptamine receptor
2004-01-03 Updated DEFINITION Combining with the biogenic amine serotonin, a neurotransmitter and hormone found in vertebrates, invertebrates and plants, to initiate a change in cell activity.
2003-05-13 Added DEFINITION The function of combining with the biogenic amine serotonin, a neurotransmitter and hormone found in vertebrates, invertebrates and plants, to initiate a change in cell function.
2003-03-19 Deleted SYNONYM 5HT receptor
2002-10-19 Added SYNONYM 5-HT receptor
2001-03-30 Added SYNONYM 5-hydroxytryptamine receptor
2001-03-30 Added SYNONYM 5HT receptor

Relationships

Timestamp Action Category Detail
2011-06-12 Added RELATION part of GO:0007210 (serotonin receptor signaling pathway)
2008-04-01 Updated RELATION is a GO:0008227 (G-protein coupled amine receptor activity)

Cross-references

Timestamp Action Category Detail
2009-02-25 Added XREF Wikipedia:5-HT_receptor

Other

Timestamp Action Category Detail
2010-10-07 Added SECONDARY GO:0016609 (G-protein coupled serotonin receptor activity)
2002-10-19 Added SECONDARY GO:0001585 (5-hydroxytryptamine receptor)
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