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GO:0022848 acetylcholine-gated cation-selective channel activity

Term Information

ID GO:0022848
Name acetylcholine-gated cation-selective channel activity
Ontology Molecular Function
Definition Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
PMID:2466967
Secondary IDs GO:0004889 GO:0016904
GONUTS GO:0022848 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact nicotinergic acetylcholine receptor activity
exact nicotinic acetylcholine-activated cation-selective channel activity
exact iontropic acetylcholine receptor activity
exact acetylcholine-gated cation channel activity
exact acetylcholine-activated cation-selective channel activity

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0099536 synaptic signaling never_in_taxon 4895 Schizosaccharomyces
More information on taxon constraints in GO is available here

Cross-Ontology Relations

Relation Other Ontology ID Term
has_input CHEBI CHEBI:15355 acetylcholine
transports_or_maintains_localization_of CHEBI CHEBI:36915 inorganic cation

Cross-references

Database ID
InterPro IPR002394
InterPro IPR032932

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0022848:
Relationship To GO:0022848 Child Term Child Term Name
Regulates GO:1903048 regulation of acetylcholine-gated cation channel activity
Negatively regulates GO:1903049 negative regulation of acetylcholine-gated cation channel activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO ID
Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0022848. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0022848 based on the entire annotation set Co-occurrence statistics for GO:0022848 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2016-12-13 Deleted RELATION is a GO:0022824 (transmitter-gated ion channel activity)
2016-12-13 Added SECONDARY GO:0016904 (nicotinic acetylcholine receptor)
2016-12-13 Added SECONDARY GO:0004889 (acetylcholine-activated cation-selective channel activity)
2016-12-13 Added SYNONYM acetylcholine-gated cation channel activity
2016-12-13 Added SYNONYM nicotinergic acetylcholine receptor activity
2016-12-13 Added SYNONYM nicotinic acetylcholine-activated cation-selective channel activity
2016-12-13 Added RELATION is a GO:0005231 (excitatory extracellular ligand-gated ion channel activity)
2016-12-13 Added RELATION is a GO:0099094 (ligand-gated cation channel activity)
2016-12-13 Added RELATION is a GO:1904315 (transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)
2016-12-13 Updated TERM acetylcholine-gated cation-selective channel activity
2016-12-13 Added DEFINITION Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
2016-12-13 Deleted DEFINITION Enables the transmembrane transfer of a cation by a channel that opens when acetylcholine has been bound by the channel complex or one of its constituent parts.
2016-12-13 Added SYNONYM iontropic acetylcholine receptor activity
2016-12-13 Added SYNONYM acetylcholine-activated cation-selective channel activity
2016-01-20 Added RELATION is a GO:0015464 (acetylcholine receptor activity)
2015-05-11 Deleted DEFINITION Catalysis of the transmembrane transfer of a cation by a channel that opens when acetylcholine has been bound by the channel complex or one of its constituent parts.
2015-05-11 Added DEFINITION Enables the transmembrane transfer of a cation by a channel that opens when acetylcholine has been bound by the channel complex or one of its constituent parts.
2008-05-13 Added DEFINITION Catalysis of the transmembrane transfer of a cation by a channel that opens when acetylcholine has been bound by the channel complex or one of its constituent parts.
2008-05-12 Deleted DEFINITION Catalysis of the transmembrane transfer of a cation by a channel that opens when acetylcholine has been bound by the channel complex or one of its constituent parts.
2008-04-01 Updated RELATION is a GO:0022824 (transmitter-gated ion channel activity)
2007-07-27 Added DEFINITION Catalysis of the transmembrane transfer of a cation by a channel that opens when acetylcholine has been bound by the channel complex or one of its constituent parts.
2007-07-11 Added TERM acetylcholine-gated cation channel activity

Term

Timestamp Action Category Detail
2016-12-13 Updated TERM acetylcholine-gated cation-selective channel activity
2007-07-11 Added TERM acetylcholine-gated cation channel activity

Definition/synonyms

Timestamp Action Category Detail
2016-12-13 Added SYNONYM acetylcholine-gated cation channel activity
2016-12-13 Added SYNONYM nicotinergic acetylcholine receptor activity
2016-12-13 Added SYNONYM nicotinic acetylcholine-activated cation-selective channel activity
2016-12-13 Added DEFINITION Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
2016-12-13 Deleted DEFINITION Enables the transmembrane transfer of a cation by a channel that opens when acetylcholine has been bound by the channel complex or one of its constituent parts.
2016-12-13 Added SYNONYM iontropic acetylcholine receptor activity
2016-12-13 Added SYNONYM acetylcholine-activated cation-selective channel activity
2015-05-11 Deleted DEFINITION Catalysis of the transmembrane transfer of a cation by a channel that opens when acetylcholine has been bound by the channel complex or one of its constituent parts.
2015-05-11 Added DEFINITION Enables the transmembrane transfer of a cation by a channel that opens when acetylcholine has been bound by the channel complex or one of its constituent parts.
2008-05-13 Added DEFINITION Catalysis of the transmembrane transfer of a cation by a channel that opens when acetylcholine has been bound by the channel complex or one of its constituent parts.
2008-05-12 Deleted DEFINITION Catalysis of the transmembrane transfer of a cation by a channel that opens when acetylcholine has been bound by the channel complex or one of its constituent parts.
2007-07-27 Added DEFINITION Catalysis of the transmembrane transfer of a cation by a channel that opens when acetylcholine has been bound by the channel complex or one of its constituent parts.

Relationships

Timestamp Action Category Detail
2016-12-13 Deleted RELATION is a GO:0022824 (transmitter-gated ion channel activity)
2016-12-13 Added RELATION is a GO:0005231 (excitatory extracellular ligand-gated ion channel activity)
2016-12-13 Added RELATION is a GO:0099094 (ligand-gated cation channel activity)
2016-12-13 Added RELATION is a GO:1904315 (transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)
2016-01-20 Added RELATION is a GO:0015464 (acetylcholine receptor activity)
2008-04-01 Updated RELATION is a GO:0022824 (transmitter-gated ion channel activity)

Other

Timestamp Action Category Detail
2016-12-13 Added SECONDARY GO:0016904 (nicotinic acetylcholine receptor)
2016-12-13 Added SECONDARY GO:0004889 (acetylcholine-activated cation-selective channel activity)
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