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GO:0004866 endopeptidase inhibitor activity

Stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.

Term Information

ID GO:0004866
Name endopeptidase inhibitor activity
Ontology Molecular Function
Definition Stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.
Comment

Synonyms

Type Synonym
related alpha-2 macroglobulin
broad proteinase inhibitor
exact endoproteinase inhibitor

Cross-references associated with this term:

Database ID
INTERPRO IPR002890
INTERPRO IPR002160
INTERPRO IPR003086
INTERPRO IPR001713
INTERPRO IPR001599
INTERPRO IPR016085
INTERPRO IPR011052

This term can be used instead of these obsolete terms:

GO:0016975 alpha-2 macroglobulin (replaced_by GO:0004866)

Web service: term information

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GTerm?id=termID&format=format

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0003674 molecular_function
GO:0030234 enzyme regulator activity
GO:0004857 enzyme inhibitor activity
GO:0030414 peptidase inhibitor activity
GO:0004866 endopeptidase inhibitor activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0008191 metalloendopeptidase inhibitor activity
I GO:0004867 serine-type endopeptidase inhibitor activity
I GO:0004869 cysteine-type endopeptidase inhibitor activity
I GO:0019828 aspartic-type endopeptidase inhibitor activity

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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