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GO:0004857 enzyme inhibitor activity

Term Information

ID GO:0004857
Name enzyme inhibitor activity
Ontology Molecular Function
Definition Stops, prevents or reduces the activity of an enzyme.
GONUTS GO:0004857 Wiki Page

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
InterPro IPR002993
InterPro IPR006501
InterPro IPR007605
InterPro IPR007648
InterPro IPR008404
InterPro IPR011061
InterPro IPR029785
UniProtKB-KW Metalloenzyme inhibitor

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0008025 diazepam binding inhibitor activity CONSIDER GO:0004857

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004857:
Relationship To GO:0004857 Child Term Child Term Name
Is a GO:0060241 lysozyme inhibitor activity
Is a GO:0046910 pectinesterase inhibitor activity
Is a GO:0046811 histone deacetylase inhibitor activity
Is a GO:0042030 ATPase inhibitor activity
Is a GO:0015066 alpha-amylase inhibitor activity
Is a GO:0030251 guanylate cyclase inhibitor activity
Is a GO:0048551 metalloenzyme inhibitor activity
Is a GO:0008073 ornithine decarboxylase inhibitor activity
Is a GO:0004858 dUTP pyrophosphatase inhibitor activity
Is a GO:0010521 telomerase inhibitor activity
Is a GO:0005095 GTPase inhibitor activity
Is a GO:0019210 kinase inhibitor activity
Is a GO:0019212 phosphatase inhibitor activity
Is a GO:0008428 ribonuclease inhibitor activity
Is a GO:0030414 peptidase inhibitor activity
Is a GO:0090369 ornithine carbamoyltransferase inhibitor activity
Is a GO:0090353 polygalacturonase inhibitor activity
Is a GO:0055102 lipase inhibitor activity
Is a GO:0055104 ligase inhibitor activity
Is a GO:0060703 deoxyribonuclease inhibitor activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004857. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004857 based on the entire annotation set Co-occurrence statistics for GO:0004857 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-04-24 Added RELATION part of GO:0043086 (negative regulation of catalytic activity)
2008-05-13 Added DEFINITION Stops, prevents or reduces the activity of an enzyme.
2008-05-12 Deleted DEFINITION Stops, prevents or reduces the activity of an enzyme.
2008-04-01 Updated RELATION is a GO:0030234 (enzyme regulator activity)
2007-10-07 Deleted SYNONYM diazepam binding inhibitor activity
2007-08-09 Added SYNONYM diazepam binding inhibitor activity
2007-08-09 Deleted SYNONYM diazepam binding inhibitor activity
2005-08-10 Added SYNONYM diazepam binding inhibitor activity
2003-04-09 Added DEFINITION Stops, prevents or reduces the activity of an enzyme.
2003-03-19 Updated TERM enzyme inhibitor activity
2003-03-19 Deleted SYNONYM enzyme modulator
2002-02-06 Updated TERM enzyme inhibitor
2002-01-08 Added SYNONYM enzyme modulator
2001-04-03 Updated TERM enzyme inhibitor
2001-03-30 Added TERM enzyme inhibitor

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM enzyme inhibitor activity
2002-02-06 Updated TERM enzyme inhibitor
2001-04-03 Updated TERM enzyme inhibitor
2001-03-30 Added TERM enzyme inhibitor

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Stops, prevents or reduces the activity of an enzyme.
2008-05-12 Deleted DEFINITION Stops, prevents or reduces the activity of an enzyme.
2007-10-07 Deleted SYNONYM diazepam binding inhibitor activity
2007-08-09 Added SYNONYM diazepam binding inhibitor activity
2007-08-09 Deleted SYNONYM diazepam binding inhibitor activity
2005-08-10 Added SYNONYM diazepam binding inhibitor activity
2003-04-09 Added DEFINITION Stops, prevents or reduces the activity of an enzyme.
2003-03-19 Deleted SYNONYM enzyme modulator
2002-01-08 Added SYNONYM enzyme modulator

Relationships

Timestamp Action Category Detail
2011-04-24 Added RELATION part of GO:0043086 (negative regulation of catalytic activity)
2008-04-01 Updated RELATION is a GO:0030234 (enzyme regulator activity)
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