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GO:0004842 ubiquitin-protein ligase activityCatalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
Term Information
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| Type | Synonym |
| exact | ubiquitin:protein-lysine N-ligase (AMP-forming) activity |
| related | ubiquitin activity |
| exact | ubiquitin-ligase activity |
| narrow | anaphase-promoting complex activity |
| exact | ubiquitin-conjugating enzyme activity |
| narrow | E2 |
| exact | ubiquitin protein ligase activity |
| exact | ubiquitin ligase activity |
| exact | ubiquitin conjugating enzyme activity |
| narrow | E3 |
| exact | ubiquitin protein-ligase activity |
| Database | ID |
| MetaCyc | UBIQUITIN--PROTEIN-LIGASE-RXN |
| EC | 6.3.2.19 |
| INTERPRO | IPR015582 |
| INTERPRO | IPR003126 |
| INTERPRO | IPR010606 |
| INTERPRO | IPR015581 |
| INTERPRO | IPR013323 |
| INTERPRO | IPR003613 |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | ||||||
![]() | GO:0003824 catalytic activity | |||||
![]() | ![]() | GO:0016874 ligase activity | ||||
![]() | ![]() | ![]() | GO:0016879 ligase activity, forming carbon-nitrogen bonds | |||
![]() | ![]() | ![]() | ![]() | GO:0016881 acid-amino acid ligase activity | ||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0019787 small conjugating protein ligase activity | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004842 ubiquitin-protein ligase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| I | GO:0034450 ubiquitin-ubiquitin ligase activity |
| I | GO:0050372 ubiquitin-calmodulin ligase activity |
| Code | Relationship |
| P | part of |
| I | is a |
| Hostname | tomcat-8.ebi.ac.uk |
| Uptime | 17:46 13/10/2009 |
| Data version | 2009-11-20-04-03-08 |