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GO:0004822 isoleucine-tRNA ligase activity

Term Information

ID GO:0004822
Name isoleucine-tRNA ligase activity
Ontology Molecular Function
Definition Catalysis of the reaction: L-isoleucine + ATP + tRNA(Ile) = L-isoleucyl-tRNA(Ile) + AMP + diphosphate + 2 H(+).
GONUTS GO:0004822 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact isoleucine translase activity
exact isoleucyl-tRNA synthetase activity
exact isoleucyl-transfer RNA synthetase activity
exact isoleucine-transfer RNA ligase activity
exact isoleucine-tRNA synthetase activity
exact L-isoleucine:tRNAIle ligase (AMP-forming)
exact isoleucyl-transfer ribonucleate synthetase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 6.1.1.5
InterPro IPR002301
InterPro IPR023585
InterPro IPR023586
KEGG R03656
MetaCyc ISOLEUCINE--TRNA-LIGASE-RXN
RHEA 11063

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004822:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004822. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004822 based on the entire annotation set Co-occurrence statistics for GO:0004822 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-11 Added DEFINITION Catalysis of the reaction: L-isoleucine + ATP + tRNA(Ile) = L-isoleucyl-tRNA(Ile) + AMP + diphosphate + 2 H(+).
2010-10-11 Deleted DEFINITION Catalysis of the reaction: ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile).
2010-10-11 Added XREF KEGG:R03656
2010-10-11 Added XREF RHEA:11063
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile).
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile).
2008-04-01 Updated RELATION is a GO:0004812 (aminoacyl-tRNA ligase activity)
2007-11-08 Added SYNONYM L-isoleucine:tRNAIle ligase (AMP-forming)
2007-11-08 Added SYNONYM isoleucine-tRNA synthetase activity
2007-11-08 Added SYNONYM isoleucine-transfer RNA ligase activity
2007-11-08 Added SYNONYM isoleucyl-transfer RNA synthetase activity
2007-11-08 Added SYNONYM isoleucyl-transfer ribonucleate synthetase activity
2007-09-06 Added SYNONYM isoleucine translase activity
2007-08-09 Added SYNONYM isoleucyl-tRNA synthetase activity
2007-08-09 Deleted SYNONYM isoleucyl-tRNA synthetase activity
2004-04-19 Added SYNONYM isoleucyl-tRNA synthetase activity
2004-04-16 Deleted SYNONYM isoleucyl-tRNA synthetase activity
2003-12-16 Added SYNONYM isoleucyl-tRNA synthetase activity
2003-10-27 Added XREF MetaCyc:ISOLEUCINE--TRNA-LIGASE-RXN
2003-03-19 Updated TERM isoleucine-tRNA ligase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile).
2002-02-06 Updated TERM isoleucine-tRNA ligase
2001-11-07 Updated TERM isoleucine-tRNA ligase
2001-04-03 Updated TERM isoleucine--tRNA ligase
2001-03-30 Added XREF EC:6.1.1.5
2001-03-30 Added TERM isoleucine--tRNA ligase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM isoleucine-tRNA ligase activity
2002-02-06 Updated TERM isoleucine-tRNA ligase
2001-11-07 Updated TERM isoleucine-tRNA ligase
2001-04-03 Updated TERM isoleucine--tRNA ligase
2001-03-30 Added TERM isoleucine--tRNA ligase

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Added DEFINITION Catalysis of the reaction: L-isoleucine + ATP + tRNA(Ile) = L-isoleucyl-tRNA(Ile) + AMP + diphosphate + 2 H(+).
2010-10-11 Deleted DEFINITION Catalysis of the reaction: ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile).
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile).
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile).
2007-11-08 Added SYNONYM L-isoleucine:tRNAIle ligase (AMP-forming)
2007-11-08 Added SYNONYM isoleucine-tRNA synthetase activity
2007-11-08 Added SYNONYM isoleucine-transfer RNA ligase activity
2007-11-08 Added SYNONYM isoleucyl-transfer RNA synthetase activity
2007-11-08 Added SYNONYM isoleucyl-transfer ribonucleate synthetase activity
2007-09-06 Added SYNONYM isoleucine translase activity
2007-08-09 Added SYNONYM isoleucyl-tRNA synthetase activity
2007-08-09 Deleted SYNONYM isoleucyl-tRNA synthetase activity
2004-04-19 Added SYNONYM isoleucyl-tRNA synthetase activity
2004-04-16 Deleted SYNONYM isoleucyl-tRNA synthetase activity
2003-12-16 Added SYNONYM isoleucyl-tRNA synthetase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile).

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004812 (aminoacyl-tRNA ligase activity)

Cross-references

Timestamp Action Category Detail
2010-10-11 Added XREF KEGG:R03656
2010-10-11 Added XREF RHEA:11063
2003-10-27 Added XREF MetaCyc:ISOLEUCINE--TRNA-LIGASE-RXN
2001-03-30 Added XREF EC:6.1.1.5
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