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GO:0004812 aminoacyl-tRNA ligase activity

Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of pyrophosphate and AMP.

Term Information

ID GO:0004812
Name aminoacyl-tRNA ligase activity
Ontology Molecular Function
Definition Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of pyrophosphate and AMP.
Comment Note that the bond resulting from this reaction is a carboxylic acid ester bond, linking the alpha carboxyl group of the amino acid to either the 2' or 3' hydroxyl of the 3'- terminal adenyl residue of the tRNA.

Synonyms

Type Synonym
exact aminoacyl-tRNA synthetase activity

Cross-references associated with this term:

Database ID
EC 6.1.1.-
INTERPRO IPR009080
INTERPRO IPR008925
INTERPRO IPR018150
INTERPRO IPR018156
INTERPRO IPR009008
INTERPRO IPR004364
INTERPRO IPR001412
INTERPRO IPR006195
INTERPRO IPR004115
INTERPRO IPR004154
INTERPRO IPR007639
INTERPRO IPR002300
INTERPRO IPR002305
INTERPRO IPR002314
INTERPRO IPR000924
INTERPRO IPR020061
INTERPRO IPR020058
INTERPRO IPR020059
INTERPRO IPR020060
INTERPRO IPR000738
INTERPRO IPR015413
INTERPRO IPR013155

Web service: term information

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016874 ligase activity
GO:0016875 ligase activity, forming carbon-oxygen bonds
GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
GO:0004812 aminoacyl-tRNA ligase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0050560 aspartate-tRNA(Asn) ligase activity
I GO:0050561 glutamate-tRNA(Gln) ligase activity
I GO:0050562 lysine-tRNA(Pyl) ligase activity
I GO:0017100 aminoacyl-tRNA synthetase auxiliary protein activity
I GO:0004813 alanine-tRNA ligase activity
I GO:0004814 arginine-tRNA ligase activity
I GO:0004815 aspartate-tRNA ligase activity
I GO:0004816 asparagine-tRNA ligase activity
I GO:0004817 cysteine-tRNA ligase activity
I GO:0004818 glutamate-tRNA ligase activity
I GO:0004819 glutamine-tRNA ligase activity
I GO:0004820 glycine-tRNA ligase activity
I GO:0004821 histidine-tRNA ligase activity
I GO:0004822 isoleucine-tRNA ligase activity
I GO:0004823 leucine-tRNA ligase activity
I GO:0004824 lysine-tRNA ligase activity
I GO:0004825 methionine-tRNA ligase activity
I GO:0004826 phenylalanine-tRNA ligase activity
I GO:0004827 proline-tRNA ligase activity
I GO:0004828 serine-tRNA ligase activity
I GO:0004829 threonine-tRNA ligase activity
I GO:0004830 tryptophan-tRNA ligase activity
I GO:0004831 tyrosine-tRNA ligase activity
I GO:0004832 valine-tRNA ligase activity
I GO:0043816 phosphoserine-tRNA(Cys) ligase activity
I GO:0043767 pyrrolysyl-tRNA synthetase activity

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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