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GO:0004725 protein tyrosine phosphatase activityCatalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
Term Information
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| Type | Synonym |
| exact | PTPase activity |
| exact | phosphotyrosine phosphatase activity |
| exact | PPT-phosphatase activity |
| exact | PTP-phosphatase activity |
| exact | [phosphotyrosine]protein phosphatase activity |
| exact | phosphoprotein phosphatase (phosphotyrosine) activity |
| exact | phosphotyrosine histone phosphatase activity |
| exact | phosphotyrosine protein phosphatase activity |
| exact | phosphotyrosylprotein phosphatase activity |
| exact | protein phosphotyrosine phosphatase activity |
| exact | protein-tyrosine-phosphatase activity |
| exact | protein-tyrosine-phosphate phosphohydrolase activity |
| exact | tyrosine O-phosphate phosphatase activity |
| exact | tyrosylprotein phosphatase activity |
| Database | ID |
| EC | 3.1.3.48 |
| MetaCyc | PROTEIN-TYROSINE-PHOSPHATASE-RXN |
| INTERPRO | IPR017867 |
| INTERPRO | IPR000242 |
| INTERPRO | IPR012265 |
| INTERPRO | IPR012266 |
| INTERPRO | IPR016130 |
| INTERPRO | IPR000106 |
| INTERPRO | IPR000751 |
| INTERPRO | IPR006945 |
| INTERPRO | IPR014393 |
| INTERPRO | IPR014064 |
| INTERPRO | IPR016334 |
| INTERPRO | IPR017361 |
| INTERPRO | IPR012151 |
| INTERPRO | IPR012152 |
| INTERPRO | IPR012153 |
| INTERPRO | IPR003546 |
| INTERPRO | IPR014392 |
| INTERPRO | IPR015103 |
| INTERPRO | IPR008356 |
| INTERPRO | IPR016336 |
| INTERPRO | IPR016667 |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | |||||||
![]() | GO:0003824 catalytic activity | ||||||
![]() | ![]() | GO:0016787 hydrolase activity | |||||
![]() | ![]() | ![]() | GO:0016788 hydrolase activity, acting on ester bonds | ||||
![]() | ![]() | ![]() | ![]() | GO:0042578 phosphoric ester hydrolase activity | |||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0016791 phosphatase activity | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004721 phosphoprotein phosphatase activity | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004725 protein tyrosine phosphatase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| I | GO:0005001 transmembrane receptor protein tyrosine phosphatase activity |
| I | GO:0004726 non-membrane spanning protein tyrosine phosphatase activity |
| I | GO:0004727 prenylated protein tyrosine phosphatase activity |
| I | GO:0004728 receptor signaling protein tyrosine phosphatase activity |
| I | GO:0030945 protein tyrosine phosphatase activity, via thiol-phosphate intermediate |
| I | GO:0030946 protein tyrosine phosphatase activity, metal-dependent |
| I | GO:0033550 MAP kinase tyrosine phosphatase activity |
| Code | Relationship |
| P | part of |
| I | is a |
| Hostname | tomcat-8.ebi.ac.uk |
| Uptime | 17:46 13/10/2009 |
| Data version | 2009-11-20-04-03-08 |