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GO:0004725 protein tyrosine phosphatase activity

Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Term Information

ID GO:0004725
Name protein tyrosine phosphatase activity
Ontology Molecular Function
Definition Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
Comment

Synonyms

Type Synonym
exact PTPase activity
exact phosphotyrosine phosphatase activity
exact PPT-phosphatase activity
exact PTP-phosphatase activity
exact [phosphotyrosine]protein phosphatase activity
exact phosphoprotein phosphatase (phosphotyrosine) activity
exact phosphotyrosine histone phosphatase activity
exact phosphotyrosine protein phosphatase activity
exact phosphotyrosylprotein phosphatase activity
exact protein phosphotyrosine phosphatase activity
exact protein-tyrosine-phosphatase activity
exact protein-tyrosine-phosphate phosphohydrolase activity
exact tyrosine O-phosphate phosphatase activity
exact tyrosylprotein phosphatase activity

Cross-references associated with this term:

Database ID
EC 3.1.3.48
MetaCyc PROTEIN-TYROSINE-PHOSPHATASE-RXN
INTERPRO IPR017867
INTERPRO IPR000242
INTERPRO IPR012265
INTERPRO IPR012266
INTERPRO IPR016130
INTERPRO IPR000106
INTERPRO IPR000751
INTERPRO IPR006945
INTERPRO IPR014393
INTERPRO IPR014064
INTERPRO IPR016334
INTERPRO IPR017361
INTERPRO IPR012151
INTERPRO IPR012152
INTERPRO IPR012153
INTERPRO IPR003546
INTERPRO IPR014392
INTERPRO IPR015103
INTERPRO IPR008356
INTERPRO IPR016336
INTERPRO IPR016667

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0042578 phosphoric ester hydrolase activity
GO:0016791 phosphatase activity
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
I GO:0004726 non-membrane spanning protein tyrosine phosphatase activity
I GO:0004727 prenylated protein tyrosine phosphatase activity
I GO:0004728 receptor signaling protein tyrosine phosphatase activity
I GO:0030945 protein tyrosine phosphatase activity, via thiol-phosphate intermediate
I GO:0030946 protein tyrosine phosphatase activity, metal-dependent
I GO:0033550 MAP kinase tyrosine phosphatase activity

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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