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GO:0004721 phosphoprotein phosphatase activity

Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.

Term Information

ID GO:0004721
Name phosphoprotein phosphatase activity
Ontology Molecular Function
Definition Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.
Comment

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_candida91
goslim_generic127
goslim_yeast93

Synonyms

Type Synonym
exact protein phosphatase activity
exact phosphoprotein phosphohydrolase activity
narrow protein phosphatase-2C activity
narrow protein phosphatase-2B activity
narrow protein phosphatase-2A activity
narrow protein phosphatase-1 activity

Cross-references associated with this term:

Database ID
INTERPRO IPR006945
INTERPRO IPR012008
INTERPRO IPR012391
INTERPRO IPR010822
EC 3.1.3.16
MetaCyc 3.1.3.16-RXN
INTERPRO IPR011236
INTERPRO IPR012911
INTERPRO IPR006811
INTERPRO IPR011943
INTERPRO IPR011947

Web service: term information

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0042578 phosphoric ester hydrolase activity
GO:0016791 phosphatase activity
GO:0004721 phosphoprotein phosphatase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0008138 protein tyrosine/serine/threonine phosphatase activity
I GO:0019198 transmembrane receptor protein phosphatase activity
I GO:0008330 protein tyrosine/threonine phosphatase activity
I GO:0004722 protein serine/threonine phosphatase activity
I GO:0004725 protein tyrosine phosphatase activity
I GO:0033549 MAP kinase phosphatase activity

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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