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GO:0004714 transmembrane receptor protein tyrosine kinase activityCatalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate, to initiate a change in cell activity.
Term Information
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| Type | Synonym |
| related | neurotrophin TRKB receptor activity |
| related | neurotrophin TRKC receptor activity |
| exact | receptor protein-tyrosine kinase activity |
| related | sevenless receptor activity |
| exact | receptor protein tyrosine kinase activity |
| broad | ATP:protein-tyrosine O-phosphotransferase activity |
| exact | ATP:protein-L-tyrosine O-phosphotransferase (receptor-type) activity |
| narrow | Drosophila Eph kinase activity |
| narrow | anaplastic lymphoma kinase activity |
| narrow | ephrin-B3 receptor tyrosine kinase activity |
| narrow | insulin receptor protein-tyrosine kinase activity |
| narrow | neurite outgrowth regulating kinase activity |
| narrow | novel oncogene with kinase-domain activity |
| related | neurotrophin TRK receptor activity |
| related | neurotrophin TRKA receptor activity |
| Database | ID |
| EC | 2.7.10.1 |
| MetaCyc | 2.7.10.1-RXN |
| INTERPRO | IPR006211 |
| INTERPRO | IPR015776 |
| INTERPRO | IPR015781 |
| INTERPRO | IPR002011 |
| INTERPRO | IPR016247 |
| INTERPRO | IPR001824 |
GO:0005016 neurotrophin TRKC receptor activity |
(consider GO:0004714) |
GO:0004927 sevenless receptor activity |
(consider GO:0004714) |
GO:0005013 neurotrophin TRK receptor activity |
(consider GO:0004714) |
GO:0005014 neurotrophin TRKA receptor activity |
(consider GO:0004714) |
GO:0005015 neurotrophin TRKB receptor activity |
(consider GO:0004714) |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | |||||||||||||
![]() | GO:0003824 catalytic activity | ||||||||||||
![]() | ![]() | GO:0060089 molecular transducer activity | |||||||||||
![]() | ![]() | ![]() | GO:0016740 transferase activity | ||||||||||
![]() | ![]() | ![]() | ![]() | GO:0004871 signal transducer activity | |||||||||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0004872 receptor activity | ||||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0016772 transferase activity, transferring phosphorus-containing groups | |||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004888 transmembrane receptor activity | ||||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0016773 phosphotransferase activity, alcohol group as acceptor | |||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0016301 kinase activity | ||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004672 protein kinase activity | |||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004713 protein tyrosine kinase activity | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0019199 transmembrane receptor protein kinase activity | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004714 transmembrane receptor protein tyrosine kinase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| I | GO:0008288 boss receptor activity |
| I | GO:0005003 ephrin receptor activity |
| I | GO:0005006 epidermal growth factor receptor activity |
| I | GO:0005007 fibroblast growth factor receptor activity |
| I | GO:0005008 hepatocyte growth factor receptor activity |
| I | GO:0005009 insulin receptor activity |
| I | GO:0005010 insulin-like growth factor receptor activity |
| I | GO:0005011 macrophage colony stimulating factor receptor activity |
| I | GO:0005017 platelet-derived growth factor receptor activity |
| I | GO:0005020 stem cell factor receptor activity |
| I | GO:0005021 vascular endothelial growth factor receptor activity |
| I | GO:0060175 brain-derived neurotrophic factor receptor activity |
| Code | Relationship |
| P | part of |
| I | is a |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-11-21-04-03-45 |